SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1w15 SYNAPTOTAGMIN IV
(Rattus
norvegicus) 		4 / 8 THR A 349
THR A 343
VAL A 376
VAL A 327
 None
 0.93A 1t86A-1w15A:
undetectable		 1t86A-1w15A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 1w15 SYNAPTOTAGMIN IV
(Rattus
norvegicus) 		5 / 12 VAL A 376
VAL A 329
LEU A 292
LEU A 291
LEU A 295
 None
 1.18A 4i1rA-1w15A:
4.3		 4i1rA-1w15A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1w15 SYNAPTOTAGMIN IV
(Rattus
norvegicus) 		4 / 8 HIS A 404
GLY A 402
GLY A 401
HIS A 420
 None
 0.78A 5f8yA-1w15A:
undetectable		 5f8yA-1w15A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1w15 SYNAPTOTAGMIN IV
(Rattus
norvegicus) 		3 / 3 THR A 349
THR A 343
LEU A 291
 None
 0.63A 5m66D-1w15A:
undetectable		 5m66D-1w15A:
18.35