SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w36'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 8 LEU C 564
PHE C 483
LEU C 571
LEU C 568
 None
 0.96A 1e7cA-1w36C:
2.2		 1e7cA-1w36C:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 SER C 199
GLU C 198
GLU C 195
 None
 0.66A 1eqbD-1w36C:
undetectable		 1eqbD-1w36C:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 SER C 199
GLU C 198
GLU C 195
 None
 0.67A 1eqbB-1w36C:
undetectable		 1eqbB-1w36C:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 ALA C 842
VAL C 974
TRP C1006
 None
 0.87A 1kqeB-1w36C:
undetectable
1kqeD-1w36C:
undetectable		 1kqeB-1w36C:
1.67
1kqeD-1w36C:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 TRP C1006
ALA C 842
VAL C 974
 None
 0.88A 1kqeB-1w36C:
undetectable
1kqeD-1w36C:
undetectable		 1kqeB-1w36C:
1.67
1kqeD-1w36C:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 TRP C1006
ALA C 842
VAL C 974
 None
 0.87A 1kqeA-1w36C:
undetectable
1kqeE-1w36C:
undetectable		 1kqeA-1w36C:
1.67
1kqeE-1w36C:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 ARG C 582
ILE C 573
TRP C 574
 None
 1.03A 1m8eB-1w36C:
undetectable		 1m8eB-1w36C:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 ILE C 342
SER C 373
ILE C 374
LEU C 751
ILE C 338
 None
 0.74A 1rb3B-1w36C:
undetectable		 1rb3B-1w36C:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 LEU C 224
LEU C 314
ILE C 213
ILE C 216
ALA C 218
 None
 1.05A 2bxcA-1w36C:
undetectable		 2bxcA-1w36C:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 LEU C 224
LEU C 314
ILE C 213
ILE C 216
ALA C 218
 None
 1.02A 2bxqA-1w36C:
0.0		 2bxqA-1w36C:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 GLU C 718
LEU C  46
GLY C 215
SER C 217
ARG C 706
 None
 1.25A 2ogyB-1w36C:
undetectable		 2ogyB-1w36C:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 SER C 758
ARG C 365
ILE C 374
PHE C 376
 None
 1.16A 2qeiA-1w36C:
undetectable		 2qeiA-1w36C:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 GLN C 181
THR C  97
TRP C  93
 None
 1.00A 2rctA-1w36C:
undetectable		 2rctA-1w36C:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA155_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 5 TRP C 917
GLY C 913
PRO C 908
PHE C 916
 None
 1.26A 2rezA-1w36C:
0.0		 2rezA-1w36C:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 9 SER C 566
LEU C 479
GLU C 559
GLY C 489
LEU C 493
 None
 1.29A 2v0mB-1w36C:
undetectable		 2v0mB-1w36C:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 7 ILE C 374
ILE C 408
LEU C 751
LEU C 678
 None
 0.84A 3adxA-1w36C:
undetectable		 3adxA-1w36C:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 8 ARG C 734
GLY C 733
VAL C 378
LEU C 783
 None
 1.04A 3bgdB-1w36C:
2.5		 3bgdB-1w36C:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 ARG C 582
ILE C 573
TRP C 574
 None
 1.10A 3e68A-1w36C:
undetectable		 3e68A-1w36C:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 ARG C 582
ILE C 573
TRP C 574
 None
 1.05A 3e6tB-1w36C:
undetectable		 3e6tB-1w36C:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 ARG C 582
ILE C 573
TRP C 574
 None
 0.99A 3e7iB-1w36C:
undetectable		 3e7iB-1w36C:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 ASN C 681
VAL C 748
ILE C 729
TYR C 728
THR C 781
 None
 1.28A 3em0A-1w36C:
0.0		 3em0A-1w36C:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 10 CYH C 662
ILE C 415
ILE C 661
VAL C 659
LEU C 664
 None
 1.23A 3em0A-1w36C:
undetectable		 3em0A-1w36C:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 LEU C  95
LEU C  98
ARG C 105
 None
 0.64A 3hcnB-1w36C:
2.4		 3hcnB-1w36C:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 LEU C 964
GLU C 983
SER C 996
PHE C1008
 None
 1.38A 3i9jB-1w36C:
undetectable		 3i9jB-1w36C:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 ARG C 582
ILE C 573
TRP C 574
 None
 0.91A 3nw2A-1w36C:
undetectable		 3nw2A-1w36C:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 9 ILE C 729
ILE C 374
VAL C 748
ILE C 755
ILE C 752
 None
 1.16A 3p4wB-1w36C:
3.2		 3p4wB-1w36C:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 10 ILE C 729
ILE C 374
VAL C 748
ILE C 755
ILE C 752
 None
 1.17A 3p4wD-1w36C:
3.1		 3p4wD-1w36C:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 10 ILE C 729
ILE C 374
VAL C 748
ILE C 755
ILE C 752
 None
 1.17A 3p4wE-1w36C:
3.1		 3p4wE-1w36C:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 HIS C 784
ARG C 799
GLU C 798
 None
 1.19A 3qf1A-1w36C:
undetectable		 3qf1A-1w36C:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 ILE C 342
SER C 373
ILE C 374
LEU C 751
ILE C 338
 None
 1.00A 3tq9A-1w36C:
undetectable		 3tq9A-1w36C:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 LEU C 239
TYR C   5
MET C  34
SER C 319
PRO C 208
 None
 1.49A 3ug8A-1w36C:
undetectable		 3ug8A-1w36C:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 LEU C 394
MET C 396
ASP C 407
 None
 0.86A 3v5wA-1w36C:
undetectable		 3v5wA-1w36C:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 TYR C 141
LEU C 224
ALA C  66
ILE C 216
LEU C  36
 None
 1.17A 3w67C-1w36C:
undetectable		 3w67C-1w36C:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 ARG C 445
ARG C 443
ILE C 455
 None
 0.89A 4b7qC-1w36C:
undetectable		 4b7qC-1w36C:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 HIS C 237
HIS C 267
GLU C  33
ASP C  28
 None
 1.15A 4blvA-1w36C:
undetectable		 4blvA-1w36C:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 5 VAL C 211
ARG C 210
MET C  34
GLU C  33
 None
 1.06A 4hojA-1w36C:
0.0		 4hojA-1w36C:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 LEU C 720
LEU C 717
LEU C 747
ILE C 374
LEU C 677
 None
 1.08A 4j24A-1w36C:
1.1		 4j24A-1w36C:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 LEU C 720
LEU C 717
LEU C 747
ILE C 374
LEU C 677
 None
 1.05A 4j24B-1w36C:
0.7		 4j24B-1w36C:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 8 ARG C 687
ASP C 441
SER C 651
SER C  39
 None
 1.14A 4lv9A-1w36C:
undetectable
4lv9B-1w36C:
undetectable		 4lv9A-1w36C:
17.75
4lv9B-1w36C:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 ILE C 729
ILE C 755
PHE C 716
LEU C 720
 None
 0.85A 4m51A-1w36C:
undetectable		 4m51A-1w36C:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 5 PHE C 526
PRO C 549
VAL C 547
ALA C 904
 None
 1.28A 4w5oA-1w36C:
2.1		 4w5oA-1w36C:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 11 LEU C 460
LEU C 457
LEU C 571
ALA C 472
LEU C 473
 None
 1.11A 4wg0B-1w36C:
undetectable
4wg0C-1w36C:
undetectable
4wg0D-1w36C:
undetectable		 4wg0B-1w36C:
1.29
4wg0C-1w36C:
1.29
4wg0D-1w36C:
1.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 11 LEU C 460
LEU C 457
LEU C 571
ALA C 472
LEU C 473
 None
 1.11A 4wg0D-1w36C:
undetectable
4wg0E-1w36C:
undetectable
4wg0F-1w36C:
undetectable		 4wg0D-1w36C:
1.29
4wg0E-1w36C:
1.29
4wg0F-1w36C:
1.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 11 LEU C 460
LEU C 457
LEU C 571
ALA C 472
LEU C 473
 None
 1.11A 4wg0F-1w36C:
undetectable
4wg0G-1w36C:
undetectable
4wg0H-1w36C:
undetectable		 4wg0F-1w36C:
1.29
4wg0G-1w36C:
1.29
4wg0H-1w36C:
1.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 11 LEU C 460
LEU C 457
LEU C 571
ALA C 472
LEU C 473
 None
 1.12A 4wg0H-1w36C:
undetectable
4wg0I-1w36C:
undetectable
4wg0J-1w36C:
undetectable		 4wg0H-1w36C:
1.29
4wg0I-1w36C:
1.29
4wg0J-1w36C:
1.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 11 ALA C 472
LEU C 473
LEU C 571
LEU C 460
LEU C 457
 None
 1.13A 4wg0G-1w36C:
undetectable
4wg0H-1w36C:
undetectable
4wg0I-1w36C:
undetectable		 4wg0G-1w36C:
1.29
4wg0H-1w36C:
1.29
4wg0I-1w36C:
1.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 11 LEU C 460
LEU C 457
LEU C 571
ALA C 472
LEU C 473
 None
 1.10A 4wg0J-1w36C:
undetectable
4wg0K-1w36C:
undetectable
4wg0L-1w36C:
undetectable		 4wg0J-1w36C:
1.29
4wg0K-1w36C:
1.29
4wg0L-1w36C:
1.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 11 ALA C 472
LEU C 473
LEU C 571
LEU C 460
LEU C 457
 None
 1.10A 4wg0I-1w36C:
undetectable
4wg0J-1w36C:
undetectable
4wg0K-1w36C:
undetectable		 4wg0I-1w36C:
1.29
4wg0J-1w36C:
1.29
4wg0K-1w36C:
1.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 11 ALA C 472
LEU C 473
LEU C 571
LEU C 460
LEU C 457
 None
 1.09A 4wg0K-1w36C:
undetectable
4wg0L-1w36C:
undetectable
4wg0M-1w36C:
undetectable		 4wg0K-1w36C:
1.29
4wg0L-1w36C:
1.29
4wg0M-1w36C:
1.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 ALA C 928
GLN C 925
LEU C 927
LEU C 884
 None
 1.07A 4xoyA-1w36C:
undetectable		 4xoyA-1w36C:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 ALA C 928
GLN C 925
LEU C 927
LEU C 884
 None
 1.06A 4xp3A-1w36C:
undetectable		 4xp3A-1w36C:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 VAL C  12
PHE C 326
ARG C 272
 None
 0.86A 4xr4B-1w36C:
undetectable		 4xr4B-1w36C:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 5 PHE C 526
PRO C 549
VAL C 547
ALA C 904
 None
 1.30A 4z4cA-1w36C:
2.5		 4z4cA-1w36C:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 5 PHE C 526
PRO C 549
VAL C 547
ALA C 904
 None
 1.29A 4z4dA-1w36C:
2.0		 4z4dA-1w36C:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 5 PHE C 526
PRO C 549
VAL C 547
ALA C 904
 None
 1.28A 4z4eA-1w36C:
1.9		 4z4eA-1w36C:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 10 PHE C 598
ALA C 597
LEU C 634
LEU C 460
LEU C 458
 None
 1.35A 4zmeB-1w36C:
undetectable		 4zmeB-1w36C:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 VAL C 659
LEU C 389
LEU C 678
VAL C 410
PHE C 426
 None
 1.13A 5im2A-1w36C:
undetectable		 5im2A-1w36C:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 12 TYR C 256
LEU C 276
GLN C 285
SER C 280
GLU C 281
 None
 1.47A 5l8oB-1w36C:
undetectable		 5l8oB-1w36C:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 SER C  84
ALA C  85
THR C 176
 None
 0.36A 5n0xB-1w36C:
0.9		 5n0xB-1w36C:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		3 / 3 GLU C 387
HIS C 390
VAL C 425
 None
 0.66A 5trqB-1w36C:
undetectable		 5trqB-1w36C:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 7 LEU C1035
TYR C1090
GLU C1084
SER C1041
 None
 0.88A 5umwA-1w36C:
undetectable
5umwF-1w36C:
undetectable		 5umwA-1w36C:
5.05
5umwF-1w36C:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 4 LEU C1020
LEU C1017
SER C 990
ALA C1013
 None
 0.93A 5uunA-1w36C:
undetectable		 5uunA-1w36C:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 7 GLU C  83
TRP C  70
ARG C 186
PRO C  81
 None
 1.50A 6a4iB-1w36C:
undetectable		 6a4iB-1w36C:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 4 TYR C 190
LEU C 313
TYR C 312
PRO C 220
 None
 1.33A 6e8qA-1w36C:
0.3		 6e8qA-1w36C:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 7 ASP C 906
GLY C 527
PHE C 526
GLY C 501
 None
 0.80A 6ekzA-1w36C:
undetectable		 6ekzA-1w36C:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		5 / 9 GLN C 165
LEU C  95
PHE C 135
LEU C 134
TRP C 169
 None
 1.28A 6ftpA-1w36C:
0.0
6ftpB-1w36C:
undetectable		 6ftpA-1w36C:
4.99
6ftpB-1w36C:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 GLY C1042
LEU C1046
PHE C1112
PHE C 840
 None
 0.77A 6h7lA-1w36C:
1.5		 6h7lA-1w36C:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 GLY C1042
LEU C1046
PHE C1112
PHE C 840
 None
 0.76A 6h7lB-1w36C:
1.5		 6h7lB-1w36C:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 GLY C1043
LEU C1046
PHE C1112
PHE C 840
 None
 1.05A 6h7lB-1w36C:
1.5		 6h7lB-1w36C:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 VAL C 684
ASN C 681
ILE C 732
GLU C 385
 None
 1.19A 6h7uA-1w36C:
undetectable		 6h7uA-1w36C:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN
(Escherichia
coli) 		4 / 6 ILE C1105
LEU C1038
ARG C1068
THR C1069
 None
 1.14A 6nmfN-1w36C:
undetectable
6nmfW-1w36C:
undetectable		 6nmfN-1w36C:
17.92
6nmfW-1w36C:
4.92