SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110
(Homo
sapiens) 		4 / 8 ALA A 370
TYR A 374
LEU A 367
GLY A 365
 None
 0.83A 1rukH-1w3bA:
undetectable
1rukL-1w3bA:
undetectable		 1rukH-1w3bA:
18.75
1rukL-1w3bA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110
(Homo
sapiens) 		3 / 3 GLY A 115
ASP A 114
SER A  83
 None
 0.73A 2qhfA-1w3bA:
undetectable		 2qhfA-1w3bA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110
(Homo
sapiens) 		5 / 12 GLY A  46
GLN A  74
SER A  64
ALA A  81
ASN A  84
 None
 1.20A 3t7sA-1w3bA:
undetectable		 3t7sA-1w3bA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110
(Homo
sapiens) 		4 / 8 LEU A 157
VAL A 133
VAL A 137
GLN A 141
 None
 0.69A 4em2A-1w3bA:
undetectable		 4em2A-1w3bA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110
(Homo
sapiens) 		4 / 5 SER A 243
HIS A 248
TYR A 218
VAL A 251
 None
 1.44A 4eohB-1w3bA:
undetectable		 4eohB-1w3bA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110
(Homo
sapiens) 		5 / 9 LEU A 221
LEU A 225
ALA A 241
VAL A 251
ALA A 234
 None
 1.43A 5g44A-1w3bA:
undetectable		 5g44A-1w3bA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110
(Homo
sapiens) 		4 / 5 ILE A 197
LEU A 187
GLY A 188
PHE A 191
 None
 0.70A 5kmdC-1w3bA:
undetectable
5kmdD-1w3bA:
undetectable		 5kmdC-1w3bA:
21.32
5kmdD-1w3bA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110
(Homo
sapiens) 		3 / 3 ASN A 291
TYR A 272
CYH A 305
 None
 0.94A 5lsuB-1w3bA:
undetectable		 5lsuB-1w3bA:
19.59