SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w3f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.91A 1fb7A-1w3fA:
undetectable		 1fb7A-1w3fA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 9 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.95A 1hxwA-1w3fA:
undetectable		 1hxwA-1w3fA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 PHE A 146
LEU A 147
LEU A  11
PRO A   7
LEU A  50
 None
 1.21A 1og5A-1w3fA:
undetectable		 1og5A-1w3fA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		4 / 5 GLY A 300
ILE A 275
VAL A 220
SER A 302
 None
 1.24A 1rs7A-1w3fA:
undetectable		 1rs7A-1w3fA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 1.00A 1sdtB-1w3fA:
undetectable		 1sdtB-1w3fA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.96A 1sduB-1w3fA:
undetectable		 1sduB-1w3fA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 10 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.96A 2aquA-1w3fA:
undetectable		 2aquA-1w3fA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.96A 2f80A-1w3fA:
undetectable		 2f80A-1w3fA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.98A 2f81A-1w3fA:
undetectable		 2f81A-1w3fA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.87A 2hs1B-1w3fA:
undetectable		 2hs1B-1w3fA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.99A 2hs2A-1w3fA:
undetectable		 2hs2A-1w3fA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.91A 2hs2B-1w3fA:
undetectable		 2hs2B-1w3fA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.87A 2nnkB-1w3fA:
undetectable		 2nnkB-1w3fA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		3 / 3 THR A 309
ASP A 271
SER A 303
 None
 0.84A 2nxeA-1w3fA:
undetectable		 2nxeA-1w3fA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		3 / 3 THR A 309
ASP A 271
SER A 303
 None
 0.83A 2nxeB-1w3fA:
undetectable		 2nxeB-1w3fA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.94A 2pymA-1w3fA:
undetectable		 2pymA-1w3fA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.97A 2pymB-1w3fA:
undetectable		 2pymB-1w3fA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 1.00A 2pynA-1w3fA:
undetectable		 2pynA-1w3fA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.98A 2q63B-1w3fA:
undetectable		 2q63B-1w3fA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 1.04A 2qhcB-1w3fA:
undetectable		 2qhcB-1w3fA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		4 / 7 TRP A 238
GLY A 300
GLN A 198
PHE A 246
 None
 1.12A 2qx4A-1w3fA:
undetectable
2qx4B-1w3fA:
undetectable		 2qx4A-1w3fA:
20.81
2qx4B-1w3fA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.97A 2z54A-1w3fA:
undetectable		 2z54A-1w3fA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.89A 3d1xB-1w3fA:
undetectable		 3d1xB-1w3fA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.90A 3d1zA-1w3fA:
undetectable		 3d1zA-1w3fA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.97A 3d20A-1w3fA:
undetectable		 3d20A-1w3fA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 11 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.88A 3el1A-1w3fA:
undetectable		 3el1A-1w3fA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.83A 3el1B-1w3fA:
undetectable		 3el1B-1w3fA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.99A 3k4vD-1w3fA:
undetectable		 3k4vD-1w3fA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		4 / 8 LEU A  36
GLN A  22
SER A  20
HIS A 125
 None
None
None
NLC  A1320 (-4.5A)
 1.11A 3kp2A-1w3fA:
undetectable
3kp2B-1w3fA:
undetectable		 3kp2A-1w3fA:
19.11
3kp2B-1w3fA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.88A 3ndtB-1w3fA:
undetectable		 3ndtB-1w3fA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.94A 3ndtC-1w3fA:
undetectable		 3ndtC-1w3fA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.91A 3ndtD-1w3fA:
undetectable		 3ndtD-1w3fA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.94A 3nduA-1w3fA:
undetectable		 3nduA-1w3fA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.91A 3nduB-1w3fA:
undetectable		 3nduB-1w3fA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.95A 3nduC-1w3fA:
undetectable		 3nduC-1w3fA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.95A 3nduD-1w3fA:
undetectable		 3nduD-1w3fA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.94A 3ndwA-1w3fA:
undetectable		 3ndwA-1w3fA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_D_ACTD601_0
(CHOLINE OXIDASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		4 / 5 TRP A 238
ILE A 156
TRP A 298
VAL A 230
 None
 1.42A 3nneD-1w3fA:
0.0		 3nneD-1w3fA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_E_ACTE601_0
(CHOLINE OXIDASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		4 / 4 TRP A 238
ILE A 156
TRP A 298
VAL A 230
 None
 1.40A 3nneE-1w3fA:
0.0		 3nneE-1w3fA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.93A 3oxcA-1w3fA:
undetectable		 3oxcA-1w3fA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 1.01A 3pwmA-1w3fA:
undetectable		 3pwmA-1w3fA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.93A 3pwrA-1w3fA:
undetectable		 3pwrA-1w3fA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
ILE A 156
GLY A 296
ILE A 297
PRO A 221
 None
 1.09A 3s56A-1w3fA:
undetectable		 3s56A-1w3fA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.91A 3tkgB-1w3fA:
undetectable		 3tkgB-1w3fA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.91A 3tkgC-1w3fA:
undetectable		 3tkgC-1w3fA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.97A 3ucbB-1w3fA:
undetectable		 3ucbB-1w3fA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		4 / 7 TYR A 104
GLN A 135
THR A 118
THR A 145
 None
 1.08A 4mbsA-1w3fA:
undetectable		 4mbsA-1w3fA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 11 GLY A 241
ILE A 156
GLY A 296
ILE A 297
VAL A 220
 None
 0.86A 4q1xA-1w3fA:
undetectable		 4q1xA-1w3fA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 10 GLY A 241
ILE A 156
GLY A 296
ILE A 297
VAL A 220
 None
 0.83A 4q1yA-1w3fA:
undetectable		 4q1yA-1w3fA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 GLY A 241
GLY A 296
ILE A 297
PRO A 221
VAL A 220
 None
 0.96A 4q5mA-1w3fA:
undetectable		 4q5mA-1w3fA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		4 / 6 TRP A 238
GLY A 300
GLN A 198
PHE A 246
 None
 1.09A 4qogA-1w3fA:
0.0
4qogB-1w3fA:
0.0		 4qogA-1w3fA:
21.12
4qogB-1w3fA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		4 / 5 PHE A  48
SER A  49
ASN A  28
GLN A  84
 None
 1.35A 5kpcA-1w3fA:
undetectable		 5kpcA-1w3fA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		5 / 12 VAL A 301
PHE A 216
TRP A 238
PHE A 246
VAL A 234
 None
 1.36A 6a94A-1w3fA:
undetectable		 6a94A-1w3fA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS
(Laetiporus
sulphureus) 		3 / 3 TYR A  47
ASP A  45
GLN A  46
 GOL  A1319 ( 4.3A)
GOL  A1315 (-3.9A)
GOL  A1315 (-3.7A)
 0.89A 6g1pA-1w3fA:
undetectable		 6g1pA-1w3fA:
23.16