SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w4s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 1w4s POLYBROMO 1 PROTEIN
(Gallus
gallus) 		4 / 4 ILE A 978
MET A1076
VAL A1015
GLY A 993
 None
 1.11A 1e06B-1w4sA:
undetectable		 1e06B-1w4sA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1w4s POLYBROMO 1 PROTEIN
(Gallus
gallus) 		4 / 8 LYS A1032
VAL A 962
TYR A 956
LEU A 991
 None
 0.99A 1z2bB-1w4sA:
undetectable		 1z2bB-1w4sA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 1w4s POLYBROMO 1 PROTEIN
(Gallus
gallus) 		4 / 6 ASP A 960
TYR A 961
TYR A 963
TYR A 956
 None
 1.23A 2w98A-1w4sA:
undetectable
2w98B-1w4sA:
undetectable		 2w98A-1w4sA:
16.62
2w98B-1w4sA:
16.62