SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 204
THR A 203
PRO A 230
 None
 0.82A 1a7yA-1w5dA:
undetectable		 1a7yA-1w5dA:
3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		8 / 12 ALA A  51
SER A  52
LYS A  55
TYR A 150
SER A 299
ASN A 301
LYS A 411
GLY A 413
 None
 0.64A 1ghmA-1w5dA:
20.2		 1ghmA-1w5dA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		8 / 12 ALA A  51
SER A  52
LYS A  55
SER A 299
ASN A 301
THR A 394
LYS A 411
GLY A 413
 None
 0.44A 1i2wA-1w5dA:
20.2		 1i2wA-1w5dA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		7 / 12 ALA A  51
SER A  52
LYS A  55
SER A 299
ASN A 301
THR A 394
GLY A 413
 None
 0.46A 1i2wB-1w5dA:
20.1		 1i2wB-1w5dA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 204
THR A 203
PRO A 230
 None
 0.84A 1i3wF-1w5dA:
undetectable		 1i3wF-1w5dA:
3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 247
ALA A 246
GLY A 271
ILE A 126
THR A  74
 None
 0.98A 1k6cB-1w5dA:
undetectable		 1k6cB-1w5dA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A 381
ALA A 410
LEU A 365
THR A 427
LEU A 459
 None
 1.14A 1og5A-1w5dA:
undetectable		 1og5A-1w5dA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  24
ASP A 450
ILE A 451
ILE A  14
 None
 0.78A 1p7lD-1w5dA:
undetectable		 1p7lD-1w5dA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  24
ASP A 450
ILE A 451
ILE A  14
 None
 0.79A 1p7lC-1w5dA:
undetectable		 1p7lC-1w5dA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 204
THR A 203
PRO A 230
 None
 0.80A 1qfiA-1w5dA:
undetectable		 1qfiA-1w5dA:
3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  24
ASP A 450
ILE A 451
ILE A  14
 None
 0.80A 1rg9B-1w5dA:
undetectable		 1rg9B-1w5dA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  24
ASP A 450
ILE A 451
ILE A  14
 None
 0.78A 1rg9A-1w5dA:
undetectable		 1rg9A-1w5dA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  24
ASP A 450
ILE A 451
ILE A  14
 None
 0.79A 1rg9D-1w5dA:
undetectable		 1rg9D-1w5dA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  24
ASP A 450
ILE A 451
ILE A  14
 None
 0.80A 1rg9C-1w5dA:
undetectable		 1rg9C-1w5dA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		7 / 12 SER A  52
LYS A  55
SER A 299
ASN A 301
THR A 394
LYS A 411
GLY A 413
 None
 0.34A 1ymxA-1w5dA:
21.0		 1ymxA-1w5dA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A  52
LYS A  55
SER A 299
ASN A 301
LYS A 411
GLY A 413
 None
 0.30A 1ymxB-1w5dA:
21.0		 1ymxB-1w5dA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 VAL A  76
LEU A 281
LEU A  93
ALA A 110
LEU A 257
 None
 1.10A 2aylA-1w5dA:
undetectable		 2aylA-1w5dA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 MET A 296
PHE A 292
SER A 380
LEU A  63
 None
 1.04A 2o01A-1w5dA:
0.0		 2o01A-1w5dA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 PHE A 292
SER A 380
ALA A  60
LEU A  63
 None
 0.95A 2o01A-1w5dA:
0.0		 2o01A-1w5dA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 GLY A  44
ASP A  45
SER A 357
 None
 0.50A 2qhfA-1w5dA:
undetectable		 2qhfA-1w5dA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 SER A 277
GLY A  95
GLU A  75
ALA A 249
 None
 0.86A 3aodA-1w5dA:
undetectable		 3aodA-1w5dA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 11 ALA A 460
VAL A 408
ILE A 437
LEU A 421
PHE A 435
 None
 1.31A 3fl9C-1w5dA:
undetectable		 3fl9C-1w5dA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 MET A 296
GLY A 423
VAL A 434
LEU A  57
ILE A 368
 None
 1.18A 3h52A-1w5dA:
undetectable		 3h52A-1w5dA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 LYS A  55
SER A 299
ASN A 301
THR A 394
LYS A 411
GLY A 413
 None
 0.44A 3hlwA-1w5dA:
21.0		 3hlwA-1w5dA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A 299
ASN A 301
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.32A 3hlwB-1w5dA:
21.0		 3hlwB-1w5dA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 LYS A  55
ASN A 301
LYS A 411
THR A 412
GLY A 413
 None
 0.37A 3huoA-1w5dA:
21.0		 3huoA-1w5dA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 TYR A 377
SER A 362
SER A  53
LEU A  56
 None
 1.11A 3lsfH-1w5dA:
undetectable		 3lsfH-1w5dA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 ALA A  51
SER A  52
LYS A  55
ASN A 301
THR A 412
GLY A 413
 None
 0.42A 3mzeA-1w5dA:
18.8		 3mzeA-1w5dA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A  52
SER A 299
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.56A 3ny4A-1w5dA:
19.5		 3ny4A-1w5dA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A  93
TYR A 248
GLY A 168
THR A 169
LEU A 250
 None
 1.33A 3okxA-1w5dA:
undetectable		 3okxA-1w5dA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 LYS A  55
SER A 299
ASN A 301
LYS A 411
GLY A 413
SER A 414
 None
 0.56A 3q07A-1w5dA:
21.0		 3q07A-1w5dA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 LYS A  55
SER A 299
ASN A 301
LYS A 411
GLY A 413
 None
 0.36A 3q07B-1w5dA:
20.9		 3q07B-1w5dA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		7 / 12 ALA A  51
SER A  52
SER A 299
ASN A 301
LYS A 411
THR A 412
GLY A 413
 None
 0.27A 3sh8A-1w5dA:
20.2		 3sh8A-1w5dA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		7 / 12 ALA A  51
SER A  52
LYS A  55
SER A 299
ASN A 301
LYS A 411
GLY A 413
 None
 0.41A 3sh8B-1w5dA:
20.2		 3sh8B-1w5dA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 5 VAL A 118
LEU A  87
ILE A 121
VAL A  76
 None
 0.84A 4a9kB-1w5dA:
undetectable		 4a9kB-1w5dA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		7 / 12 LYS A  55
SER A 299
ASN A 301
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.49A 4euzA-1w5dA:
19.7		 4euzA-1w5dA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 10 SER A 299
ASN A 301
LYS A 411
THR A 412
GLY A 413
ALA A  51
 None
 1.46A 4fh2A-1w5dA:
21.9		 4fh2A-1w5dA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 11 ALA A  59
ALA A  60
ALA A  61
THR A 331
LEU A 344
 None
 1.08A 4j6cA-1w5dA:
undetectable		 4j6cA-1w5dA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 ALA A  59
ALA A  60
ALA A  61
THR A 331
LEU A 344
 None
 1.08A 4j6cB-1w5dA:
undetectable		 4j6cB-1w5dA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ALA A  59
ALA A  60
ALA A  61
THR A 331
LEU A 344
 None
 1.06A 4j6dA-1w5dA:
undetectable		 4j6dA-1w5dA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ALA A  59
ALA A  60
ALA A  61
THR A 331
LEU A 344
 None
 1.05A 4j6dB-1w5dA:
undetectable		 4j6dB-1w5dA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ALA A  59
ALA A  60
ALA A  61
THR A 331
LEU A 344
 None
 1.10A 4jbtA-1w5dA:
undetectable		 4jbtA-1w5dA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 11 ALA A  59
ALA A  60
ALA A  61
THR A 331
LEU A 344
 None
 1.09A 4jbtB-1w5dA:
undetectable		 4jbtB-1w5dA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  24
ASP A 450
ILE A 451
ILE A  14
 None
 0.83A 4kttB-1w5dA:
undetectable		 4kttB-1w5dA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  24
ASP A 450
ILE A 451
ILE A  14
 None
 0.79A 4kttD-1w5dA:
undetectable		 4kttD-1w5dA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ALA A 456
LEU A 365
PHE A 374
LYS A 297
GLY A 392
 None
 1.16A 4kykA-1w5dA:
undetectable
4kykB-1w5dA:
undetectable		 4kykA-1w5dA:
18.74
4kykB-1w5dA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 9 ASP A 200
PRO A 176
VAL A 174
ALA A 185
GLY A 227
 None
 1.32A 4mmbA-1w5dA:
undetectable		 4mmbA-1w5dA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 200
PRO A 176
VAL A 174
ALA A 185
GLY A 227
 None
 1.36A 4mmdA-1w5dA:
undetectable		 4mmdA-1w5dA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		7 / 12 ALA A  51
SER A  52
SER A 299
ASN A 301
LYS A 411
THR A 412
GLY A 413
 None
 0.29A 4n9kA-1w5dA:
20.4		 4n9kA-1w5dA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		7 / 12 ALA A  51
SER A  52
SER A 299
ASN A 301
LYS A 411
THR A 412
GLY A 413
 None
 0.30A 4n9kB-1w5dA:
20.4		 4n9kB-1w5dA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 GLY A 413
ALA A  51
SER A  53
LEU A  54
LEU A  56
LEU A  57
 None
 1.44A 4o1zA-1w5dA:
undetectable		 4o1zA-1w5dA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ASN A 301
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.31A 4pm5A-1w5dA:
21.0		 4pm5A-1w5dA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 LYS A  55
ASN A 301
THR A 394
LYS A 411
GLY A 413
 None
 0.48A 4pm7A-1w5dA:
21.1		 4pm7A-1w5dA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 LYS A  55
SER A 299
ASN A 301
LYS A 411
GLY A 413
 None
 0.73A 4pm7A-1w5dA:
21.1		 4pm7A-1w5dA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ASN A 301
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.35A 4pm9A-1w5dA:
21.1		 4pm9A-1w5dA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 SER A 330
ALA A  61
ASP A 354
GLU A 305
LEU A  54
 None
 1.46A 4zjoA-1w5dA:
0.0		 4zjoA-1w5dA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 LEU A 459
ALA A 456
LEU A 421
GLY A 448
HIS A  18
 None
 1.38A 5dx3A-1w5dA:
undetectable		 5dx3A-1w5dA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 ALA A  51
SER A  52
SER A 299
ASN A 301
LYS A 411
GLY A 413
 None
 0.30A 5ghyA-1w5dA:
20.1		 5ghyA-1w5dA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 ALA A  51
SER A  52
SER A 299
ASN A 301
LYS A 411
GLY A 413
 None
 0.27A 5ghyB-1w5dA:
19.8		 5ghyB-1w5dA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		7 / 11 ALA A  51
SER A  52
SER A 299
ASN A 301
LYS A 411
THR A 412
GLY A 413
 None
 0.28A 5ghzA-1w5dA:
20.3		 5ghzA-1w5dA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		7 / 10 ALA A  51
SER A  52
SER A 299
ASN A 301
LYS A 411
THR A 412
GLY A 413
 None
 0.28A 5ghzB-1w5dA:
20.3		 5ghzB-1w5dA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ASP A 105
ALA A 249
ALA A 159
GLY A  95
THR A  74
 None
 1.00A 5igjA-1w5dA:
undetectable		 5igjA-1w5dA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 6 GLY A 219
ASP A 129
ILE A 154
TYR A 194
 None
 1.12A 5iwuA-1w5dA:
undetectable		 5iwuA-1w5dA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 VAL A  76
LEU A 281
LEU A  93
ALA A 110
LEU A 257
 None
 1.11A 5jvzB-1w5dA:
undetectable		 5jvzB-1w5dA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A  24
ASP A 450
ILE A 451
ILE A  14
 None
 0.80A 5t8sA-1w5dA:
undetectable		 5t8sA-1w5dA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 ILE A 197
VAL A 186
PRO A 184
 None
 0.44A 5uunA-1w5dA:
undetectable		 5uunA-1w5dA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 SER A  43
VAL A  30
SER A 362
LEU A  15
LEU A 439
 None
 1.34A 6a93B-1w5dA:
undetectable		 6a93B-1w5dA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A  52
SER A 299
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.49A 6b5yB-1w5dA:
20.2		 6b5yB-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A  52
SER A 299
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.54A 6b5yD-1w5dA:
20.2		 6b5yD-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A  52
SER A 299
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.32A 6b68B-1w5dA:
20.2		 6b68B-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 SER A  52
SER A 299
THR A 394
LYS A 411
GLY A 413
 None
 0.35A 6b68D-1w5dA:
20.2		 6b68D-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A  52
SER A 299
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.34A 6b69A-1w5dA:
19.9
6b69B-1w5dA:
20.2		 6b69A-1w5dA:
11.48
6b69B-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A  52
SER A 299
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.32A 6b69D-1w5dA:
20.1		 6b69D-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A  52
SER A 299
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.38A 6b6aB-1w5dA:
20.3		 6b6aB-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 SER A  52
SER A 299
LYS A 411
THR A 412
GLY A 413
 None
 0.33A 6b6aD-1w5dA:
20.3		 6b6aD-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 SER A  52
SER A 299
LYS A 411
THR A 412
GLY A 413
 None
 0.38A 6b6cA-1w5dA:
19.7		 6b6cA-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 SER A  52
SER A 299
THR A 394
LYS A 411
THR A 412
GLY A 413
 None
 0.42A 6b6eA-1w5dA:
20.2		 6b6eA-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 SER A  52
SER A 299
LYS A 411
THR A 412
GLY A 413
 None
 0.49A 6b6fA-1w5dA:
20.0		 6b6fA-1w5dA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 7 SER A  53
SER A 422
GLY A 423
LEU A 438
 None
 1.10A 6btxA-1w5dA:
undetectable		 6btxA-1w5dA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 SER A 299
ASN A 301
THR A 394
LYS A 411
GLY A 413
 None
 0.32A 6c79A-1w5dA:
21.0		 6c79A-1w5dA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ASP A 128
ARG A 136
ALA A 246
GLY A  97
GLY A  95
 None
 1.29A 6clxA-1w5dA:
undetectable		 6clxA-1w5dA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1w5d PENICILLIN-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 LEU A 344
GLY A 349
PHE A 295
 None
 0.60A 6exiC-1w5dA:
undetectable		 6exiC-1w5dA:
9.40