SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w61'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 6 GLY A 131
SER A 305
THR A 304
PHE A 333
 PYC  A 700 (-3.7A)
None
None
None
 1.06A 1icuA-1w61A:
undetectable
1icuB-1w61A:
undetectable		 1icuA-1w61A:
20.54
1icuB-1w61A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 6 SER A 305
THR A 304
PHE A 333
GLY A 131
 None
None
None
PYC  A 700 (-3.7A)
 1.00A 1kqbA-1w61A:
undetectable
1kqbB-1w61A:
undetectable		 1kqbA-1w61A:
19.86
1kqbB-1w61A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 5 GLY A 131
SER A 305
THR A 304
PHE A 333
 PYC  A 700 (-3.7A)
None
None
None
 1.10A 1kqbA-1w61A:
undetectable
1kqbB-1w61A:
undetectable		 1kqbA-1w61A:
19.86
1kqbB-1w61A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 6 SER A 305
THR A 304
PHE A 333
GLY A 131
 None
None
None
PYC  A 700 (-3.7A)
 1.03A 1kqbC-1w61A:
undetectable
1kqbD-1w61A:
undetectable		 1kqbC-1w61A:
19.86
1kqbD-1w61A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_B_CLWB907_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 5 PRO A 224
VAL A 211
TYR A 274
GLU A 272
 None
 1.42A 1m9jB-1w61A:
1.0		 1m9jB-1w61A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 11 VAL A 350
LEU A 359
LEU A 193
PHE A 192
THR A 351
 None
 1.31A 1mmtA-1w61A:
undetectable		 1mmtA-1w61A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 7 LYS A  77
LEU A  80
GLN A  81
LEU A  65
 None
 0.91A 1v55P-1w61A:
undetectable
1v55W-1w61A:
undetectable		 1v55P-1w61A:
20.61
1v55W-1w61A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 7 LYS A  77
LEU A  80
GLN A  81
LEU A  65
 None
 0.88A 2dysC-1w61A:
undetectable
2dysJ-1w61A:
undetectable		 2dysC-1w61A:
20.61
2dysJ-1w61A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 7 LYS A  77
LEU A  80
GLN A  81
LEU A  65
 None
 0.90A 2eijP-1w61A:
undetectable
2eijW-1w61A:
undetectable		 2eijP-1w61A:
20.61
2eijW-1w61A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 8 LYS A  77
LEU A  80
GLN A  81
LEU A  65
 None
 0.82A 2eilP-1w61A:
undetectable
2eilW-1w61A:
undetectable		 2eilP-1w61A:
20.61
2eilW-1w61A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 ILE A 365
ALA A 363
MET A 308
SER A 191
ILE A 222
 None
 0.97A 2h77A-1w61A:
undetectable		 2h77A-1w61A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 7 GLY A 165
THR A 162
PHE A 215
PHE A 192
 None
 1.02A 2qx4A-1w61A:
undetectable
2qx4B-1w61A:
undetectable		 2qx4A-1w61A:
20.43
2qx4B-1w61A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 VAL A 271
GLN A 195
ARG A 248
ILE A 251
ASN A 252
 None
 1.26A 2vdyA-1w61A:
undetectable		 2vdyA-1w61A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 VAL A 271
GLN A 195
ARG A 248
ILE A 251
ASN A 252
 None
 1.32A 2vdyB-1w61A:
undetectable		 2vdyB-1w61A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 GLY A 301
GLY A 335
SER A 305
THR A 322
GLU A 364
 PYC  A 700 (-3.7A)
None
None
None
None
 1.21A 2wa2A-1w61A:
undetectable		 2wa2A-1w61A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 6 ALA A 136
ALA A 140
THR A 144
PHE A 374
 None
 0.67A 2xfhA-1w61A:
undetectable		 2xfhA-1w61A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 7 ARG A  59
PHE A  46
MET A 377
PHE A 379
 None
 0.99A 2zseA-1w61A:
undetectable		 2zseA-1w61A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 7 LYS A  77
LEU A  80
GLN A  81
LEU A  65
 None
 0.87A 2zxwC-1w61A:
undetectable
2zxwJ-1w61A:
undetectable		 2zxwC-1w61A:
20.61
2zxwJ-1w61A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 6 ARG A  59
PHE A  46
MET A 377
PHE A 379
 None
 0.92A 3af3A-1w61A:
0.0		 3af3A-1w61A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 8 LYS A  77
LEU A  80
GLN A  81
LEU A  65
 None
 0.96A 3asoC-1w61A:
undetectable
3asoJ-1w61A:
undetectable		 3asoC-1w61A:
20.61
3asoJ-1w61A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_1
(SPERMIDINE SYNTHASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 5 GLN A 241
GLN A 393
ASP A 100
ASP A 122
 None
 1.45A 3bwcB-1w61A:
0.2		 3bwcB-1w61A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 ARG A  88
ASN A 218
PHE A 290
ARG A 248
ILE A 265
 None
None
PYC  A 700 (-3.7A)
None
None
 1.21A 3k13C-1w61A:
undetectable		 3k13C-1w61A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 8 PHE A 120
SER A 134
LEU A 116
ASP A 161
 None
 0.81A 3m0wE-1w61A:
undetectable
3m0wF-1w61A:
undetectable
3m0wG-1w61A:
undetectable
3m0wH-1w61A:
undetectable		 3m0wE-1w61A:
13.33
3m0wF-1w61A:
13.33
3m0wG-1w61A:
13.33
3m0wH-1w61A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 9 VAL A 268
ILE A 213
ALA A 306
THR A 310
VAL A 211
 None
 1.17A 3me6C-1w61A:
undetectable		 3me6C-1w61A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 9 VAL A 268
ILE A 213
ALA A 306
THR A 310
VAL A 211
 None
 1.14A 3me6D-1w61A:
undetectable		 3me6D-1w61A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 7 GLU A 143
SER A 179
VAL A 181
VAL A 149
 None
 0.79A 3n61A-1w61A:
undetectable
3n61B-1w61A:
undetectable		 3n61A-1w61A:
19.96
3n61B-1w61A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 8 GLU A 143
SER A 179
VAL A 181
VAL A 149
 None
 0.80A 3nlrA-1w61A:
undetectable
3nlrB-1w61A:
undetectable		 3nlrA-1w61A:
19.96
3nlrB-1w61A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 LEU A 106
GLY A 103
GLY A 131
ILE A 135
ILE A 118
 None
None
PYC  A 700 (-3.7A)
None
None
 0.94A 3oxcB-1w61A:
undetectable		 3oxcB-1w61A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 8 GLY A 216
SER A 305
ASP A 296
SER A 298
 None
None
PYC  A 700 (-3.3A)
PYC  A 700 ( 4.3A)
 0.84A 3pwwA-1w61A:
undetectable		 3pwwA-1w61A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 ILE A 273
GLY A 244
ILE A 251
VAL A 255
LEU A 202
 None
 1.19A 4a81A-1w61A:
undetectable		 4a81A-1w61A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_A_MIYA391_1
(TETX2 PROTEIN)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 10 MET A 129
ASN A 133
GLY A 301
SER A 305
GLY A 169
 None
None
PYC  A 700 (-3.7A)
None
None
 1.05A 4a99A-1w61A:
undetectable		 4a99A-1w61A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 VAL A 271
GLN A 195
ARG A 248
ILE A 251
ASN A 252
 None
 1.37A 4c49C-1w61A:
undetectable		 4c49C-1w61A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 LEU A 106
GLY A 103
GLY A 131
ILE A 135
ILE A 118
 None
None
PYC  A 700 (-3.7A)
None
None
 0.99A 4jecB-1w61A:
undetectable		 4jecB-1w61A:
12.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		6 / 9 GLY A 131
ASP A 296
SER A 298
CYH A 300
GLY A 301
THR A 302
 PYC  A 700 (-3.7A)
PYC  A 700 (-3.3A)
PYC  A 700 ( 4.3A)
PYC  A 700 (-3.4A)
PYC  A 700 (-3.7A)
PYC  A 700 (-2.6A)
 0.27A 4lb0A-1w61A:
46.7		 4lb0A-1w61A:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 LEU A 160
LEU A 116
GLY A 117
MET A  51
MET A  73
 None
 1.40A 4oktA-1w61A:
undetectable		 4oktA-1w61A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 11 GLY A 301
GLY A 303
GLY A 367
GLN A 334
PHE A 323
 PYC  A 700 (-3.7A)
None
None
None
None
 1.14A 4qoiA-1w61A:
undetectable
4qoiB-1w61A:
undetectable		 4qoiA-1w61A:
20.43
4qoiB-1w61A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 7 LYS A  77
LEU A  80
GLN A  81
LEU A  65
 None
 0.94A 5b3sP-1w61A:
undetectable		 5b3sP-1w61A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 7 GLY A 244
VAL A 211
ILE A 222
VAL A 223
 None
 0.75A 5ik1A-1w61A:
undetectable		 5ik1A-1w61A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 6 ILE A 135
GLY A 216
ASN A 218
ILE A 365
 None
 0.84A 5j4nB-1w61A:
undetectable		 5j4nB-1w61A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 GLY A 131
ALA A 164
LEU A 262
GLY A 216
SER A 191
 PYC  A 700 (-3.7A)
None
None
None
None
 1.41A 5jglB-1w61A:
undetectable		 5jglB-1w61A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 6 GLN A 241
CYH A 300
THR A 302
PHE A 220
 None
PYC  A 700 (-3.4A)
PYC  A 700 (-2.6A)
None
 1.22A 5mwyA-1w61A:
undetectable		 5mwyA-1w61A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		5 / 12 ARG A 336
GLY A 335
LEU A 359
GLY A 339
ILE A 319
 None
 1.11A 5vooC-1w61A:
undetectable		 5vooC-1w61A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 1w61 B-CELL MITOGEN
(Trypanosoma
cruzi) 		4 / 6 GLN A 235
ASN A 236
VAL A 234
LEU A 329
 None
 1.36A 5xdhA-1w61A:
0.0
5xdhC-1w61A:
undetectable		 5xdhA-1w61A:
11.53
5xdhC-1w61A:
11.53