SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w78'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 4 ARG A 186
ALA A 189
ALA A 213
GLU A 215
 None
KCX  A 188 ( 3.7A)
None
None
 1.22A 1e7bA-1w78A:
undetectable		 1e7bA-1w78A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 4 ARG A 186
ALA A 189
ALA A 213
GLU A 215
 None
KCX  A 188 ( 3.7A)
None
None
 1.17A 1e7bB-1w78A:
undetectable		 1e7bB-1w78A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 5 ARG A 186
ALA A 189
ALA A 213
GLU A 215
 None
KCX  A 188 ( 3.7A)
None
None
 1.15A 1e7cA-1w78A:
undetectable		 1e7cA-1w78A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.31A 1fk9A-1w78A:
undetectable		 1fk9A-1w78A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.15A 1fkoA-1w78A:
0.6		 1fkoA-1w78A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 ALA A 282
LEU A 252
LEU A 262
ALA A 261
LEU A 248
 None
 0.99A 1g5yB-1w78A:
undetectable		 1g5yB-1w78A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 9 GLY A  59
GLY A 201
THR A  63
THR A 260
ILE A 199
 ADP  A1425 (-3.0A)
None
None
None
None
 1.21A 1gtfD-1w78A:
undetectable
1gtfE-1w78A:
undetectable		 1gtfD-1w78A:
10.85
1gtfE-1w78A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 9 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.29A 1ikvA-1w78A:
1.1		 1ikvA-1w78A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 LEU A 134
VAL A 143
VAL A  95
TYR A  81
GLY A  79
 None
 1.24A 1ikwA-1w78A:
0.1		 1ikwA-1w78A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.26A 1ikwA-1w78A:
0.1		 1ikwA-1w78A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 11 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.33A 1jkhA-1w78A:
0.0
1jkhB-1w78A:
0.1		 1jkhA-1w78A:
20.21
1jkhB-1w78A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.32A 1lw0A-1w78A:
undetectable		 1lw0A-1w78A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.29A 1s1uA-1w78A:
0.7		 1s1uA-1w78A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 7 TYR A  89
HIS A 105
TYR A  81
ILE A 112
 None
 1.04A 1tuvA-1w78A:
undetectable		 1tuvA-1w78A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 ILE A 158
ALA A 155
ARG A  92
LEU A  42
ILE A 112
 None
PD8  A1421 (-3.9A)
PD8  A1421 ( 4.9A)
None
None
 1.29A 1y0xX-1w78A:
undetectable		 1y0xX-1w78A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A  32
GLY A 190
GLY A 151
LEU A 149
GLY A 148
 None
KCX  A 188 ( 4.1A)
KCX  A 188 ( 4.1A)
PD8  A1421 ( 4.4A)
PD8  A1421 (-4.0A)
 0.93A 1y4lA-1w78A:
undetectable		 1y4lA-1w78A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 11 TYR A  81
SER A 130
LEU A 134
ILE A 158
ALA A 155
 None
None
None
None
PD8  A1421 (-3.9A)
 1.46A 2a58A-1w78A:
3.7
2a58E-1w78A:
3.7		 2a58A-1w78A:
17.49
2a58E-1w78A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 11 ILE A 158
ALA A 155
TYR A  81
SER A 130
LEU A 134
 None
PD8  A1421 (-3.9A)
None
None
None
 1.46A 2a58C-1w78A:
3.4
2a58D-1w78A:
3.8		 2a58C-1w78A:
17.49
2a58D-1w78A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 4 LEU A  30
SER A 183
ASP A 175
ASP A 335
 PD8  A1421 ( 4.7A)
None
None
None
 1.26A 2br4B-1w78A:
undetectable		 2br4B-1w78A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 7 ARG A 316
GLU A 311
ALA A 304
ASN A 306
 None
None
ADP  A1425 (-3.1A)
None
 1.04A 2ejfA-1w78A:
undetectable		 2ejfA-1w78A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 11 ALA A 310
VAL A 348
CYH A 401
GLY A 402
ILE A 330
 None
 1.25A 2uxpB-1w78A:
undetectable		 2uxpB-1w78A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 8 PRO A  84
VAL A 303
SER A 403
ALA A 408
 PD8  A1421 (-4.5A)
ADP  A1425 (-4.2A)
None
None
 1.01A 2v32A-1w78A:
undetectable
2v32B-1w78A:
undetectable		 2v32A-1w78A:
20.95
2v32B-1w78A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 4 ARG A  94
GLY A  79
GLU A  68
SER A 108
 None
 1.28A 2xctS-1w78A:
undetectable
2xctU-1w78A:
1.1		 2xctS-1w78A:
21.20
2xctU-1w78A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 8 GLY A 224
ASN A 228
TYR A 229
ARG A 223
 None
 1.40A 3ccfA-1w78A:
undetectable		 3ccfA-1w78A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 129
ALA A 131
LEU A 145
LEU A  32
ALA A  39
 None
 1.07A 3dfrA-1w78A:
3.8		 3dfrA-1w78A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 11 ASP A 172
ILE A 184
GLY A 151
ILE A 191
ILE A 169
 MG  A1422 ( 4.8A)
KCX  A 188 ( 4.9A)
KCX  A 188 ( 4.1A)
KCX  A 188 ( 3.9A)
None
 1.04A 3ebzA-1w78A:
0.0		 3ebzA-1w78A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 VAL A 381
ALA A 387
ALA A 388
LEU A 327
CYH A 401
 None
 0.79A 3fc6C-1w78A:
undetectable		 3fc6C-1w78A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 331
ALA A 339
GLY A 340
LEU A 345
ILE A 330
 None
 0.97A 3ku1A-1w78A:
2.0		 3ku1A-1w78A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 TYR A  89
LEU A 145
SER A  83
VAL A 159
LEU A  32
 None
None
PD8  A1421 ( 3.7A)
None
None
 1.33A 3m7rA-1w78A:
undetectable		 3m7rA-1w78A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 134
VAL A 143
VAL A  95
TYR A  81
GLY A  79
 None
 1.33A 3medA-1w78A:
undetectable
3medB-1w78A:
undetectable		 3medA-1w78A:
20.21
3medB-1w78A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.30A 3medA-1w78A:
undetectable
3medB-1w78A:
undetectable		 3medA-1w78A:
20.21
3medB-1w78A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 11 ASP A 172
ILE A 184
GLY A 151
ILE A 191
ILE A 169
 MG  A1422 ( 4.8A)
KCX  A 188 ( 4.9A)
KCX  A 188 ( 4.1A)
KCX  A 188 ( 3.9A)
None
 1.00A 3s53B-1w78A:
undetectable		 3s53B-1w78A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 6 LEU A 357
PRO A 356
GLU A 358
SER A 380
 None
 1.31A 3vlnA-1w78A:
undetectable		 3vlnA-1w78A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 4 ILE A 209
VAL A 165
VAL A 200
ARG A 222
 None
 1.22A 4m6tA-1w78A:
undetectable		 4m6tA-1w78A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 6 ALA A 328
LEU A 372
THR A 341
LEU A 342
 None
 0.74A 4o0uA-1w78A:
undetectable		 4o0uA-1w78A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 12 CYH A 401
SER A 403
MET A 317
LEU A 368
LEU A 357
 None
 1.11A 4o8fB-1w78A:
undetectable		 4o8fB-1w78A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 8 ASP A 415
SER A 419
ARG A 418
ARG A 417
 None
 1.17A 4uhxA-1w78A:
undetectable		 4uhxA-1w78A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		4 / 6 SER A  36
GLY A 190
ARG A 152
GLY A 151
 None
KCX  A 188 ( 4.1A)
None
KCX  A 188 ( 4.1A)
 0.90A 5cdnR-1w78A:
undetectable
5cdnS-1w78A:
undetectable		 5cdnR-1w78A:
23.83
5cdnS-1w78A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		3 / 3 GLY A 150
LEU A 149
HIS A 173
 KCX  A 188 ( 3.4A)
PD8  A1421 ( 4.4A)
MG  A1422 ( 3.4A)
 0.67A 5u63A-1w78A:
2.3		 5u63A-1w78A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.30A 6bsgA-1w78A:
undetectable		 6bsgA-1w78A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 LEU A 134
VAL A 143
VAL A  95
TYR A  81
GLY A  79
 None
 1.29A 6bsiA-1w78A:
0.0		 6bsiA-1w78A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.30A 6bsiA-1w78A:
0.0		 6bsiA-1w78A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 LEU A 134
VAL A 143
VAL A  95
TYR A  81
GLY A  79
 None
 1.30A 6bsjA-1w78A:
0.0		 6bsjA-1w78A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1w78 FOLC BIFUNCTIONAL
PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 143
VAL A  95
TYR A  81
GLY A  79
LEU A 132
 None
 1.28A 6bsjA-1w78A:
0.0		 6bsjA-1w78A:
12.68