SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 8 GLY A 541
THR A 543
LEU A 109
ASP A 113
 None
 0.62A 1aegA-1w7cA:
undetectable		 1aegA-1w7cA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 9 VAL A 494
VAL A 372
LEU A 375
ILE A 614
LEU A 492
 None
 0.98A 1eqgA-1w7cA:
undetectable		 1eqgA-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 11 VAL A 494
VAL A 372
LEU A 375
ILE A 614
LEU A 492
 None
 0.99A 1eqgB-1w7cA:
undetectable		 1eqgB-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 11 VAL A 494
VAL A 372
LEU A 375
TYR A 720
LEU A 492
 None
 1.03A 1eqgB-1w7cA:
undetectable		 1eqgB-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 12 VAL A 494
VAL A 372
LEU A 375
ILE A 614
LEU A 492
 None
 0.97A 1eqhA-1w7cA:
undetectable		 1eqhA-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 12 VAL A 494
VAL A 372
LEU A 375
TYR A 720
LEU A 492
 None
 1.01A 1eqhA-1w7cA:
undetectable		 1eqhA-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 12 VAL A 494
VAL A 372
LEU A 375
ILE A 614
LEU A 492
 None
 1.00A 1eqhB-1w7cA:
undetectable		 1eqhB-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 6 ILE A 502
SER A 526
ASN A 391
THR A 394
 TPQ  A 478 ( 4.8A)
None
None
None
 1.03A 1h7xA-1w7cA:
undetectable		 1h7xA-1w7cA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 6 ILE A 502
SER A 526
ASN A 391
THR A 394
 TPQ  A 478 ( 4.8A)
None
None
None
 1.01A 1h7xB-1w7cA:
undetectable		 1h7xB-1w7cA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 6 ILE A 502
SER A 526
ASN A 391
THR A 394
 TPQ  A 478 ( 4.8A)
None
None
None
 1.02A 1h7xC-1w7cA:
undetectable		 1h7xC-1w7cA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 6 ILE A 502
SER A 526
ASN A 391
THR A 394
 TPQ  A 478 ( 4.8A)
None
None
None
 1.02A 1h7xD-1w7cA:
undetectable		 1h7xD-1w7cA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		8 / 10 TYR A 384
THR A 474
ASN A 477
ASP A 479
TYR A 480
HIS A 528
HIS A 530
HIS A 694
 TPQ  A 478 ( 4.7A)
TPQ  A 478 ( 3.7A)
IMD  A 821 (-2.7A)
TPQ  A 478 ( 3.8A)
TPQ  A 478 ( 3.9A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.66A 1ivvA-1w7cA:
37.1		 1ivvA-1w7cA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_B_DAHB382_1
(AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		8 / 10 TYR A 384
THR A 474
ASN A 477
ASP A 479
TYR A 480
HIS A 528
HIS A 530
HIS A 694
 TPQ  A 478 ( 4.7A)
TPQ  A 478 ( 3.7A)
IMD  A 821 (-2.7A)
TPQ  A 478 ( 3.8A)
TPQ  A 478 ( 3.9A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.70A 1ivvB-1w7cA:
36.9		 1ivvB-1w7cA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 8 ILE A 296
ILE A 203
GLU A 200
VAL A 205
ILE A 235
 CL  A 813 ( 4.7A)
None
None
None
None
 1.44A 1linA-1w7cA:
undetectable		 1linA-1w7cA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 11 SER A  78
LEU A  76
THR A  79
THR A 125
VAL A  69
 None
 1.19A 1pkvA-1w7cA:
undetectable
1pkvB-1w7cA:
undetectable		 1pkvA-1w7cA:
8.19
1pkvB-1w7cA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 11 VAL A  69
SER A  78
LEU A  76
THR A  79
THR A 125
 None
 1.22A 1pkvA-1w7cA:
undetectable
1pkvB-1w7cA:
undetectable		 1pkvA-1w7cA:
8.19
1pkvB-1w7cA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.14A 1rjoA-1w7cA:
37.3		 1rjoA-1w7cA:
25.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.05A 1rkyA-1w7cA:
65.6		 1rkyA-1w7cA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 7 THR A 423
GLU A 340
SER A  63
VAL A  69
 NAG  A1786 (-3.0A)
None
MG  A 804 ( 4.0A)
None
 1.20A 1tv8A-1w7cA:
undetectable		 1tv8A-1w7cA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 12 ASN A 661
TYR A 664
ALA A 382
ALA A 215
LEU A 219
 None
None
TPQ  A 478 ( 4.6A)
None
None
 1.14A 1udtA-1w7cA:
undetectable		 1udtA-1w7cA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.53A 1v54A-1w7cA:
undetectable		 1v54A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.54A 1v54N-1w7cA:
undetectable		 1v54N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.55A 1v55A-1w7cA:
undetectable		 1v55A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.56A 1v55N-1w7cA:
undetectable		 1v55N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.23A 1w2zA-1w7cA:
41.1		 1w2zA-1w7cA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.19A 1w2zB-1w7cA:
41.1		 1w2zB-1w7cA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.19A 1w2zC-1w7cA:
41.1		 1w2zC-1w7cA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.17A 1w2zD-1w7cA:
41.6		 1w2zD-1w7cA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 6 ALA A 657
SER A 400
THR A 660
ASN A 661
 None
 1.00A 1yvpB-1w7cA:
undetectable		 1yvpB-1w7cA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 7 LEU A 644
GLY A 593
ILE A 594
ILE A 585
 None
 0.79A 2aojB-1w7cA:
undetectable		 2aojB-1w7cA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 12 GLY A 505
PHE A 390
SER A 386
VAL A 245
ALA A 504
 None
 1.23A 2avdA-1w7cA:
undetectable		 2avdA-1w7cA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.52A 2dyrA-1w7cA:
undetectable		 2dyrA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.54A 2dyrN-1w7cA:
undetectable		 2dyrN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.51A 2dysA-1w7cA:
undetectable		 2dysA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.51A 2dysN-1w7cA:
undetectable		 2dysN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.52A 2eijA-1w7cA:
undetectable		 2eijA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.55A 2eijN-1w7cA:
undetectable		 2eijN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.52A 2eikA-1w7cA:
undetectable		 2eikA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.57A 2eikN-1w7cA:
undetectable		 2eikN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.51A 2eilA-1w7cA:
undetectable		 2eilA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.56A 2eilN-1w7cA:
undetectable		 2eilN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.58A 2eimA-1w7cA:
undetectable		 2eimA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.56A 2eimN-1w7cA:
undetectable		 2eimN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.49A 2einA-1w7cA:
0.0		 2einA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 2einN-1w7cA:
0.0		 2einN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 7 TYR A 480
GLY A 402
ASN A 405
ASP A 175
 TPQ  A 478 ( 3.9A)
None
None
None
 1.03A 2g72B-1w7cA:
undetectable		 2g72B-1w7cA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.17A 2oqeA-1w7cA:
39.9		 2oqeA-1w7cA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.18A 2oqeB-1w7cA:
39.7		 2oqeB-1w7cA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.15A 2oqeC-1w7cA:
40.0		 2oqeC-1w7cA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.16A 2oqeD-1w7cA:
39.6		 2oqeD-1w7cA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.17A 2oqeF-1w7cA:
39.8		 2oqeF-1w7cA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		6 / 7 ALA A 382
TYR A 384
TYR A 396
ASP A 398
TYR A 480
HIS A 530
 TPQ  A 478 ( 4.6A)
TPQ  A 478 ( 4.7A)
IMD  A 821 (-3.5A)
IMD  A 821 (-2.6A)
TPQ  A 478 ( 3.9A)
CU  A 801 (-3.2A)
 0.52A 2pncA-1w7cA:
39.9		 2pncA-1w7cA:
28.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_B_CLUB809_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 6 ALA A 382
TYR A 396
ASP A 398
TYR A 480
HIS A 530
 TPQ  A 478 ( 4.6A)
IMD  A 821 (-3.5A)
IMD  A 821 (-2.6A)
TPQ  A 478 ( 3.9A)
CU  A 801 (-3.2A)
 0.48A 2pncB-1w7cA:
43.7		 2pncB-1w7cA:
28.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.16A 2w0qA-1w7cA:
40.1		 2w0qA-1w7cA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.19A 2w0qB-1w7cA:
39.2		 2w0qB-1w7cA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.61A 2y69A-1w7cA:
undetectable		 2y69A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.66A 2y69N-1w7cA:
undetectable		 2y69N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.61A 2zxwA-1w7cA:
undetectable		 2zxwA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.61A 2zxwN-1w7cA:
undetectable		 2zxwN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.60A 3abkA-1w7cA:
undetectable		 3abkA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.62A 3abkN-1w7cA:
undetectable		 3abkN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.58A 3ablA-1w7cA:
undetectable		 3ablA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 3ablN-1w7cA:
undetectable		 3ablN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.60A 3abmA-1w7cA:
undetectable		 3abmA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.61A 3abmN-1w7cA:
undetectable		 3abmN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.61A 3ag1A-1w7cA:
undetectable		 3ag1A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.64A 3ag1N-1w7cA:
undetectable		 3ag1N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.60A 3ag2A-1w7cA:
undetectable		 3ag2A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.61A 3ag2N-1w7cA:
undetectable		 3ag2N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.61A 3ag3A-1w7cA:
undetectable		 3ag3A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.61A 3ag3N-1w7cA:
undetectable		 3ag3N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.64A 3ag4A-1w7cA:
undetectable		 3ag4A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.63A 3ag4N-1w7cA:
undetectable		 3ag4N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 3asnA-1w7cA:
undetectable		 3asnA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.62A 3asnN-1w7cA:
undetectable		 3asnN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 3asoA-1w7cA:
undetectable		 3asoA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 3asoN-1w7cA:
undetectable		 3asoN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.78A 3bvdA-1w7cA:
undetectable		 3bvdA-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 5 LEU A 301
THR A 237
HIS A 520
LEU A 523
 None
 1.20A 3ce6D-1w7cA:
undetectable		 3ce6D-1w7cA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.64A 3dtuA-1w7cA:
undetectable		 3dtuA-1w7cA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.64A 3dtuC-1w7cA:
undetectable		 3dtuC-1w7cA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 GLY A 420
PRO A 411
LEU A 437
 CL  A 815 (-3.6A)
None
None
 0.60A 3hcpB-1w7cA:
undetectable		 3hcpB-1w7cA:
18.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.17A 3hiiA-1w7cA:
44.9		 3hiiA-1w7cA:
31.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 528
HIS A 530
HIS A 694
 CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
CU  A 801 (-3.1A)
 0.15A 3hiiB-1w7cA:
44.9		 3hiiB-1w7cA:
31.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 10 LEU A 658
VAL A 126
TRP A  97
TYR A  94
ILE A 177
 None
 1.21A 3kz7A-1w7cA:
undetectable		 3kz7A-1w7cA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 8 TYR A 396
ASP A 388
TYR A 384
SER A 526
 IMD  A 821 (-3.5A)
None
TPQ  A 478 ( 4.7A)
None
 0.98A 3rodA-1w7cA:
undetectable		 3rodA-1w7cA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 8 TYR A 396
SER A 386
TYR A 384
SER A 526
 IMD  A 821 (-3.5A)
None
TPQ  A 478 ( 4.7A)
None
 1.07A 3rodA-1w7cA:
undetectable		 3rodA-1w7cA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.70A 3s33A-1w7cA:
0.0		 3s33A-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.72A 3s38A-1w7cA:
undetectable		 3s38A-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.66A 3s39A-1w7cA:
0.0		 3s39A-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.76A 3s3aA-1w7cA:
undetectable		 3s3aA-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.69A 3s3bA-1w7cA:
0.0		 3s3bA-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.72A 3s3cA-1w7cA:
undetectable		 3s3cA-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.65A 3s3dA-1w7cA:
undetectable		 3s3dA-1w7cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 7 ASN A 189
GLN A 218
TYR A 230
TYR A 268
 None
 1.07A 3ugrA-1w7cA:
undetectable		 3ugrA-1w7cA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.58A 3wg7A-1w7cA:
undetectable		 3wg7A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.58A 3wg7N-1w7cA:
undetectable		 3wg7N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.57A 3x2qA-1w7cA:
undetectable		 3x2qA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.60A 3x2qN-1w7cA:
undetectable		 3x2qN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 7 THR A 394
TYR A 401
LEU A 174
PHE A 390
 None
IMD  A 821 ( 3.2A)
None
None
 1.22A 4awuA-1w7cA:
undetectable		 4awuA-1w7cA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 PHE A 471
TYR A 534
TYR A 484
 None
 0.74A 4ffwA-1w7cA:
2.6		 4ffwA-1w7cA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 6 GLU A 374
GLN A 378
VAL A 668
THR A 161
 None
 1.36A 4lnxA-1w7cA:
undetectable		 4lnxA-1w7cA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 7 THR A 645
TRP A 687
TRP A 637
LEU A 674
 None
 1.36A 4nsbA-1w7cA:
undetectable		 4nsbA-1w7cA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 5 ILE A 597
PHE A 673
SER A 548
ASP A 683
 None
None
None
CA  A 802 (-3.2A)
 1.40A 4rzvB-1w7cA:
0.4		 4rzvB-1w7cA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 4 GLY A 541
LEU A 492
PHE A 486
ILE A 364
 None
 0.91A 4xv2A-1w7cA:
undetectable		 4xv2A-1w7cA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.57A 5b1aA-1w7cA:
undetectable		 5b1aA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 5b1aN-1w7cA:
undetectable		 5b1aN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.58A 5b1bA-1w7cA:
undetectable		 5b1bA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.58A 5b1bN-1w7cA:
undetectable		 5b1bN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.57A 5b3sA-1w7cA:
undetectable		 5b3sA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.58A 5b3sN-1w7cA:
undetectable		 5b3sN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 11 LEU A 658
VAL A 126
TRP A  97
TYR A  94
ILE A 177
 None
 1.18A 5gpgA-1w7cA:
undetectable		 5gpgA-1w7cA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 TRP A 637
ILE A 399
SER A 397
 None
 0.95A 5gqbA-1w7cA:
undetectable		 5gqbA-1w7cA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 12 LEU A 377
SER A 654
TRP A 637
VAL A 531
HIS A 530
 None
None
None
None
CU  A 801 (-3.2A)
 1.48A 5h1eA-1w7cA:
0.0		 5h1eA-1w7cA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 12 ASP A 479
THR A 426
PHE A 407
THR A 423
SER A 473
 TPQ  A 478 ( 3.8A)
None
None
NAG  A1786 (-3.0A)
None
 1.36A 5hfjH-1w7cA:
undetectable		 5hfjH-1w7cA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 5iy5A-1w7cA:
undetectable		 5iy5A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 5iy5N-1w7cA:
undetectable		 5iy5N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 8 ASN A 122
PRO A 120
GLU A 107
TYR A 362
 NAG  A1781 ( 4.1A)
NAG  A1781 ( 3.9A)
NAG  A1781 ( 4.9A)
None
 1.43A 5oh1C-1w7cA:
0.5		 5oh1C-1w7cA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.66A 5w97a-1w7cA:
undetectable		 5w97a-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.64A 5waua-1w7cA:
undetectable		 5waua-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.60A 5x19A-1w7cA:
undetectable		 5x19A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.63A 5x19N-1w7cA:
undetectable		 5x19N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.63A 5x1bA-1w7cA:
undetectable		 5x1bA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.62A 5x1bN-1w7cA:
undetectable		 5x1bN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.65A 5x1fA-1w7cA:
undetectable		 5x1fA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.62A 5x1fN-1w7cA:
undetectable		 5x1fN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.63A 5xdqA-1w7cA:
undetectable		 5xdqA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.64A 5xdqN-1w7cA:
undetectable		 5xdqN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.62A 5xdxA-1w7cA:
undetectable		 5xdxA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.63A 5xdxN-1w7cA:
undetectable		 5xdxN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.58A 5z84A-1w7cA:
undetectable		 5z84A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 5z84N-1w7cA:
undetectable		 5z84N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.60A 5z85A-1w7cA:
undetectable		 5z85A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.58A 5z85N-1w7cA:
undetectable		 5z85N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.61A 5z86A-1w7cA:
undetectable		 5z86A-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.65A 5z86N-1w7cA:
undetectable		 5z86N-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 5zcoA-1w7cA:
undetectable		 5zcoA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.56A 5zcoN-1w7cA:
undetectable		 5zcoN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.57A 5zcpA-1w7cA:
undetectable		 5zcpA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.60A 5zcpN-1w7cA:
undetectable		 5zcpN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.57A 5zcqA-1w7cA:
undetectable		 5zcqA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.57A 5zcqN-1w7cA:
undetectable		 5zcqN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA607_0
(ALPHA-AMYLASE)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 4 ARG A 355
SER A 354
ASP A 356
ASN A 405
 None
 1.48A 6ag0A-1w7cA:
0.0		 6ag0A-1w7cA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 TYR A 270
ASN A 508
LEU A 293
 None
 0.77A 6b58A-1w7cA:
0.0		 6b58A-1w7cA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 GLY A 143
THR A 152
GLU A 154
 None
None
NAG  A1782 ( 4.3A)
 0.58A 6b58A-1w7cA:
undetectable		 6b58A-1w7cA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		5 / 12 ILE A  82
TYR A 136
ASN A  93
LEU A  76
LEU A  96
 None
 1.47A 6chgC-1w7cA:
undetectable		 6chgC-1w7cA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		4 / 6 LEU A 523
ALA A 504
LEU A 301
THR A 237
 None
 0.89A 6f88B-1w7cA:
undetectable		 6f88B-1w7cA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.72A 6hu9a-1w7cA:
undetectable		 6hu9a-1w7cA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.71A 6hu9m-1w7cA:
undetectable		 6hu9m-1w7cA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.59A 6nknA-1w7cA:
undetectable		 6nknA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.62A 6nknN-1w7cA:
undetectable		 6nknN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.62A 6nmfA-1w7cA:
undetectable		 6nmfA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.67A 6nmfN-1w7cA:
undetectable		 6nmfN-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.68A 6nmpA-1w7cA:
undetectable		 6nmpA-1w7cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1w7c LYSYL OXIDASE
(Komagataella
pastoris) 		3 / 3 HIS A 694
HIS A 528
HIS A 530
 CU  A 801 (-3.1A)
CU  A 801 (-3.2A)
CU  A 801 (-3.2A)
 0.68A 6nmpN-1w7cA:
undetectable		 6nmpN-1w7cA:
22.03