SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w7w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 1w7w NUCLEOSIDE
DIPHOSPHATE KINASE
(Pisum
sativum) 		3 / 3 PRO A 122
ASP A 120
ASP A 127
 None
 0.75A 1sqfA-1w7wA:
undetectable		 1sqfA-1w7wA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1w7w NUCLEOSIDE
DIPHOSPHATE KINASE
(Pisum
sativum) 		3 / 4 SER A  98
GLY A 118
GLU A   4
 None
 0.65A 3raeA-1w7wA:
undetectable
3raeC-1w7wA:
undetectable		 3raeA-1w7wA:
16.47
3raeC-1w7wA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 1w7w NUCLEOSIDE
DIPHOSPHATE KINASE
(Pisum
sativum) 		4 / 6 GLY A 105
ARG A  17
GLU A  22
ARG A  26
 None
 0.93A 4bqfA-1w7wA:
undetectable		 4bqfA-1w7wA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_A_LURA201_1
(TRANSTHYRETIN)		 1w7w NUCLEOSIDE
DIPHOSPHATE KINASE
(Pisum
sativum) 		4 / 4 LYS A  38
LEU A  40
ALA A  74
VAL A  76
 None
 1.08A 4ik6A-1w7wA:
0.0		 4ik6A-1w7wA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 1w7w NUCLEOSIDE
DIPHOSPHATE KINASE
(Pisum
sativum) 		3 / 4 SER A  98
GLY A 118
GLU A   4
 None
 0.60A 4juoA-1w7wA:
undetectable
4juoC-1w7wA:
undetectable		 4juoA-1w7wA:
16.47
4juoC-1w7wA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1w7w NUCLEOSIDE
DIPHOSPHATE KINASE
(Pisum
sativum) 		4 / 4 LEU A  89
ARG A 104
ILE A 103
ILE A 116
 None
 1.09A 5dzk2-1w7wA:
undetectable
5dzkM-1w7wA:
undetectable
5dzkN-1w7wA:
undetectable		 5dzk2-1w7wA:
3.17
5dzkM-1w7wA:
21.59
5dzkN-1w7wA:
21.59