SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCR_B_CHDB924_0 (FERROCHELATASE, MITOCHONDRIAL)	1w94	PROBABLE BRIX-DOMAIN RIBOSOMAL BIOGENESIS PROTEIN (Methanothermobac ter thermautotrophic us)	4 / 7	LEU A 3 ARG A 14 GLY A 32 MET A 34	None	1.04A	3hcrB-1w94A: undetectable	3hcrB-1w94A: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S79_A_ASDA601_1 (CYTOCHROME P450 19A1)	1w94	PROBABLE BRIX-DOMAIN RIBOSOMAL BIOGENESIS PROTEIN (Methanothermobac ter thermautotrophic us)	5 / 12	ILE A 23 ALA A 142 LEU A 103 MET A 107 LEU A 146	None	1.19A	3s79A-1w94A: undetectable	3s79A-1w94A: 15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JKV_A_ASDA602_1 (AROMATASE)	1w94	PROBABLE BRIX-DOMAIN RIBOSOMAL BIOGENESIS PROTEIN (Methanothermobac ter thermautotrophic us)	5 / 12	ILE A 23 ALA A 142 LEU A 103 MET A 107 LEU A 146	None	1.18A	5jkvA-1w94A: undetectable	5jkvA-1w94A: 15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA312_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	1w94	PROBABLE BRIX-DOMAIN RIBOSOMAL BIOGENESIS PROTEIN (Methanothermobac ter thermautotrophic us)	3 / 3	ILE A 60 VAL A 50 PRO A 57	None	0.70A	5uunA-1w94A: undetectable	5uunA-1w94A: 19.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3HCR_B_CHDB924_0","FERROCHELATASE, MITOCHONDRIAL","1w94","PROBABLE BRIX-DOMAIN RIBOSOMAL BIOGENESIS PROTEIN","Methanothermobacter thermautotrophicus",4,"LEU A   3;ARG A  14;GLY A  32;MET A  34","None","1.04A","3hcrB-1w94A:undetectable","3hcrB-1w94A:18.21"],["3S79_A_ASDA601_1","CYTOCHROME P450 19A1","1w94","PROBABLE BRIX-DOMAIN RIBOSOMAL BIOGENESIS PROTEIN","Methanothermobacter thermautotrophicus",5,"ILE A  23;ALA A 142;LEU A 103;MET A 107;LEU A 146","None","1.19A","3s79A-1w94A:undetectable","3s79A-1w94A:15.18"],["5JKV_A_ASDA602_1","AROMATASE","1w94","PROBABLE BRIX-DOMAIN RIBOSOMAL BIOGENESIS PROTEIN","Methanothermobacter thermautotrophicus",5,"ILE A  23;ALA A 142;LEU A 103;MET A 107;LEU A 146","None","1.18A","5jkvA-1w94A:undetectable","5jkvA-1w94A:15.18"],["5UUN_A_ACTA312_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","1w94","PROBABLE BRIX-DOMAIN RIBOSOMAL BIOGENESIS PROTEIN","Methanothermobacter thermautotrophicus",3,"ILE A  60;VAL A  50;PRO A  57","None","0.70A","5uunA-1w94A:undetectable","5uunA-1w94A:19.80"]]