SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1w9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		6 / 12 TYR A  58
LEU A 201
ASP A 236
ALA A 237
HIS A 332
ASP A 333
 AC1  A1492 ( 3.9A)
AC1  A1492 ( 4.9A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.66A 1dedA-1w9xA:
25.7		 1dedA-1w9xA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 TYR A  58
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 3.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.65A 1dedB-1w9xA:
27.7		 1dedB-1w9xA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 12 TYR A  58
HIS A 240
HIS A 332
ASP A 333
TRP A  15
 AC1  A1492 ( 3.9A)
AC1  A1492 ( 3.9A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
None
 1.27A 1eswA-1w9xA:
15.2		 1eswA-1w9xA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 6 ALA A 300
TRP A 413
ARG A 359
LEU A 297
 None
 1.18A 1gahA-1w9xA:
undetectable		 1gahA-1w9xA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 12 TRP A  15
HIS A 107
ALA A 237
GLU A 266
ASP A 333
 None
AC1  A1492 (-4.3A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 ( 3.0A)
 0.70A 1kxhA-1w9xA:
28.3		 1kxhA-1w9xA:
24.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		9 / 12 TRP A  15
TYR A  58
ARG A 234
ASP A 236
LYS A 239
GLU A 266
TRP A 268
HIS A 332
ASP A 333
 None
AC1  A1492 ( 3.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
GLC  A1491 (-2.5A)
AC1  A1492 (-2.8A)
None
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.81A 1mxdA-1w9xA:
39.1		 1mxdA-1w9xA:
32.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		9 / 12 TRP A  15
TYR A  58
HIS A 107
ARG A 234
ASP A 236
LYS A 239
GLU A 266
HIS A 332
ASP A 333
 None
AC1  A1492 ( 3.9A)
AC1  A1492 (-4.3A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
GLC  A1491 (-2.5A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.33A 1mxdA-1w9xA:
39.1		 1mxdA-1w9xA:
32.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 THR A 246
LEU A 250
VAL A 253
 None
 0.49A 1mz9E-1w9xA:
undetectable		 1mz9E-1w9xA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 ILE A 429
ILE A 410
THR A 414
 None
 0.62A 1rg7A-1w9xA:
undetectable		 1rg7A-1w9xA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 11 TYR A  58
ASP A 236
HIS A 332
ASP A 333
TRP A  15
 AC1  A1492 ( 3.9A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
None
 0.96A 2owcA-1w9xA:
14.9		 2owcA-1w9xA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 11 TYR A  58
ASP A 236
HIS A 332
ASP A 333
TRP A  15
 AC1  A1492 ( 3.9A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
None
 0.98A 2owwA-1w9xA:
14.8		 2owwA-1w9xA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 7 ASP A  62
TYR A  64
TYR A 152
THR A 151
 None
 1.49A 2q6kA-1w9xA:
undetectable		 2q6kA-1w9xA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 ASN A  54
ASN A  19
ARG A  76
 None
 0.93A 2rlcA-1w9xA:
undetectable		 2rlcA-1w9xA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.62A 3aicA-1w9xA:
11.6		 3aicA-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.59A 3aicB-1w9xA:
11.5		 3aicB-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
TYR A  58
 AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
AC1  A1492 ( 3.9A)
 0.60A 3aicC-1w9xA:
11.7		 3aicC-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.65A 3aicD-1w9xA:
11.7		 3aicD-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.64A 3aicE-1w9xA:
11.7		 3aicE-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.62A 3aicF-1w9xA:
11.6		 3aicF-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.58A 3aicG-1w9xA:
11.7		 3aicG-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.68A 3aicH-1w9xA:
11.7		 3aicH-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 5 VAL A 120
GLN A 129
PHE A 173
ARG A 181
 None
 1.49A 3bjwE-1w9xA:
0.0		 3bjwE-1w9xA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 GLY A 425
GLY A 399
GLY A 417
 None
 0.42A 3bogD-1w9xA:
undetectable		 3bogD-1w9xA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 10 LEU A 293
ALA A 352
ILE A 386
PRO A 364
THR A 327
 None
 1.09A 3el5A-1w9xA:
undetectable		 3el5A-1w9xA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 4 GLY A 101
TYR A 100
GLY A 232
ASP A 231
 None
 1.13A 3kl3A-1w9xA:
13.8		 3kl3A-1w9xA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 GLN A 319
ASP A 403
GLN A 401
 None
 0.92A 4aztA-1w9xA:
undetectable		 4aztA-1w9xA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 1.08A 4b7nA-1w9xA:
undetectable		 4b7nA-1w9xA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 1.18A 4cpzC-1w9xA:
undetectable		 4cpzC-1w9xA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 1.15A 4cpzE-1w9xA:
undetectable		 4cpzE-1w9xA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 1.08A 4cpzF-1w9xA:
undetectable		 4cpzF-1w9xA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 1.13A 4cpzG-1w9xA:
undetectable		 4cpzG-1w9xA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 ARG A 359
ARG A 415
TRP A 413
 None
 1.11A 4cpzH-1w9xA:
undetectable		 4cpzH-1w9xA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 PHE A 155
ASP A 144
ARG A 158
 None
 0.83A 4eahF-1w9xA:
1.7		 4eahF-1w9xA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		3 / 3 PHE A 155
ASP A 144
ARG A 158
 None
 0.82A 4eahG-1w9xA:
1.7		 4eahG-1w9xA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 6 SER A 365
GLY A 232
ASP A 231
GLY A 101
 None
 0.99A 4koeA-1w9xA:
undetectable
4koeB-1w9xA:
undetectable
4koeC-1w9xA:
undetectable		 4koeA-1w9xA:
19.14
4koeB-1w9xA:
19.14
4koeC-1w9xA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 8 GLY A 399
THR A 420
TYR A 398
ASN A 418
 None
 1.23A 4m5mA-1w9xA:
undetectable		 4m5mA-1w9xA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 5 ILE A  39
PHE A 396
SER A 365
ASP A 387
 None
 1.10A 4rzvB-1w9xA:
undetectable		 4rzvB-1w9xA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 6 GLY A 232
ASP A 231
GLY A 101
SER A 365
 None
 0.95A 4z53A-1w9xA:
undetectable
4z53B-1w9xA:
undetectable		 4z53A-1w9xA:
20.63
4z53B-1w9xA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 7 GLY A 232
ASP A 231
GLY A 101
SER A 365
 None
 0.93A 4z53A-1w9xA:
undetectable
4z53B-1w9xA:
undetectable		 4z53A-1w9xA:
20.63
4z53B-1w9xA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 12 ARG A 234
ASP A 236
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.50A 5csyB-1w9xA:
5.0		 5csyB-1w9xA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5H_C_ACTC1743_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 5 LYS A 349
ASP A 370
PHE A 343
PRO A 380
 None
 1.41A 5g5hA-1w9xA:
0.0
5g5hC-1w9xA:
0.0		 5g5hA-1w9xA:
19.18
5g5hC-1w9xA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 5 ARG A 218
THR A 251
HIS A 252
ASP A 248
 None
 1.37A 5mfxA-1w9xA:
undetectable		 5mfxA-1w9xA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		6 / 12 ALA A 397
TYR A 398
ILE A 464
TRP A 469
ALA A 470
ALA A 427
 None
 1.50A 5n5dB-1w9xA:
undetectable		 5n5dB-1w9xA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 12 ASP A 308
LEU A 297
ALA A 300
SER A 303
PHE A 348
 None
 1.24A 5nd4B-1w9xA:
3.0		 5nd4B-1w9xA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 12 PRO A  46
VAL A 104
ILE A 241
LEU A 250
THR A 246
 None
 1.20A 5tiwB-1w9xA:
undetectable		 5tiwB-1w9xA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 7 PHE A 262
GLY A 232
GLY A 101
THR A 257
 None
 0.81A 5ybbB-1w9xA:
undetectable		 5ybbB-1w9xA:
20.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 8 TYR A 160
GLY A 182
LYS A 185
ASP A 207
ASP A 209
HIS A 210
PRO A 211
 None
None
None
CA  A1487 (-2.9A)
CA  A1487 (-3.6A)
None
None
 0.59A 6ag0A-1w9xA:
64.2		 6ag0A-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 7 GLY A 304
GLY A 305
GLY A 433
PRO A 434
GLY A 476
 None
CA  A1488 (-4.2A)
None
None
None
 0.91A 6ag0A-1w9xA:
64.2		 6ag0A-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 7 GLY A 304
GLY A 305
TRP A 347
GLY A 433
PRO A 434
GLY A 476
GLY A 477
 None
CA  A1488 (-4.2A)
None
None
None
None
None
 0.37A 6ag0A-1w9xA:
64.2		 6ag0A-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 6 GLY A   7
THR A  40
GLN A  98
TYR A 100
TYR A 363
 None
 0.32A 6ag0A-1w9xA:
64.2		 6ag0A-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 7 LYS A  72
GLY A 110
TRP A 140
ASP A 166
TRP A 167
MET A 202
TYR A 203
 AC1  A1496 (-2.9A)
AC1  A1496 (-3.4A)
AC1  A1496 (-3.7A)
GLC  A1495 (-2.7A)
AC1  A1496 (-4.7A)
GLC  A1493 (-3.5A)
GLC  A1495 (-4.0A)
 0.30A 6ag0A-1w9xA:
64.2		 6ag0A-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		12 / 12 TRP A  15
TYR A  58
HIS A 107
GLU A 194
TYR A 198
LEU A 201
MET A 202
ASP A 236
LYS A 239
HIS A 240
HIS A 332
ASP A 333
 None
AC1  A1492 ( 3.9A)
AC1  A1492 (-4.3A)
GLC  A1491 (-2.9A)
GLC  A1491 ( 4.7A)
AC1  A1492 ( 4.9A)
GLC  A1493 (-3.5A)
AC1  A1492 (-3.0A)
GLC  A1491 (-2.5A)
AC1  A1492 ( 3.9A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.32A 6ag0A-1w9xA:
64.2		 6ag0A-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 8 TYR A 160
GLY A 182
LYS A 185
ASP A 207
ASP A 209
HIS A 210
PRO A 211
 None
None
None
CA  A1487 (-2.9A)
CA  A1487 (-3.6A)
None
None
 0.61A 6ag0C-1w9xA:
64.3		 6ag0C-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 6 GLY A   7
THR A  40
GLN A  98
TYR A 100
TYR A 363
 None
 0.29A 6ag0C-1w9xA:
64.3		 6ag0C-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 6 GLY A 304
TRP A 347
GLY A 433
PRO A 434
GLY A 477
 None
 0.33A 6ag0C-1w9xA:
64.3		 6ag0C-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		10 / 12 TRP A  15
GLU A 194
TYR A 198
LEU A 201
MET A 202
ASP A 236
LYS A 239
HIS A 240
HIS A 332
ASP A 333
 None
GLC  A1491 (-2.9A)
GLC  A1491 ( 4.7A)
AC1  A1492 ( 4.9A)
GLC  A1493 (-3.5A)
AC1  A1492 (-3.0A)
GLC  A1491 (-2.5A)
AC1  A1492 ( 3.9A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.34A 6ag0C-1w9xA:
64.3		 6ag0C-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 TRP A  15
LEU A 201
MET A 202
ASP A 236
TYR A 295
HIS A 332
ASP A 333
 None
AC1  A1492 ( 4.9A)
GLC  A1493 (-3.5A)
AC1  A1492 (-3.0A)
BGC  A1490 ( 4.5A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.75A 6ag0C-1w9xA:
64.3		 6ag0C-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 7 LYS A  72
GLY A 110
TRP A 140
ASP A 166
TRP A 167
MET A 202
TYR A 203
 AC1  A1496 (-2.9A)
AC1  A1496 (-3.4A)
AC1  A1496 (-3.7A)
GLC  A1495 (-2.7A)
AC1  A1496 (-4.7A)
GLC  A1493 (-3.5A)
GLC  A1495 (-4.0A)
 0.28A 6ag0C-1w9xA:
64.3		 6ag0C-1w9xA:
32.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 8 ARG A 234
VAL A 213
ARG A 148
GLN A  71
 AC1  A1492 (-3.3A)
None
None
None
 1.21A 6fbvD-1w9xA:
undetectable		 6fbvD-1w9xA:
16.60