SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FMJ_A_RTLA401_0
(RETINOL DEHYDRATASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 11 TYR 1 434
SER 1 460
HIS 1 244
HIS 1 352
ILE 1 424
 None
None
MN  1 602 (-3.3A)
MN  1 601 (-3.6A)
None
 1.15A 1fmjA-1wao1:
0.0		 1fmjA-1wao1:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FMJ_B_RTLB501_0
(RETINOL DEHYDRATASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 10 TYR 1 434
SER 1 460
HIS 1 244
HIS 1 352
ILE 1 424
 None
None
MN  1 602 (-3.3A)
MN  1 601 (-3.6A)
None
 1.14A 1fmjB-1wao1:
0.0		 1fmjB-1wao1:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 TYR 1 434
SER 1 460
HIS 1 244
HIS 1 352
ILE 1 424
 None
None
MN  1 602 (-3.3A)
MN  1 601 (-3.6A)
None
 1.16A 1fmlA-1wao1:
undetectable		 1fmlA-1wao1:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 TYR 1 434
SER 1 460
HIS 1 244
HIS 1 352
ILE 1 424
 None
None
MN  1 602 (-3.3A)
MN  1 601 (-3.6A)
None
 1.16A 1fmlB-1wao1:
undetectable		 1fmlB-1wao1:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 5 PHE 1 254
SER 1 447
THR 1 243
PHE 1 268
 None
 1.23A 1icuC-1wao1:
undetectable
1icuD-1wao1:
undetectable		 1icuC-1wao1:
19.18
1icuD-1wao1:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 5 PHE 1 254
SER 1 447
THR 1 243
PHE 1 268
 None
 1.30A 1icvA-1wao1:
undetectable
1icvB-1wao1:
undetectable		 1icvA-1wao1:
19.18
1icvB-1wao1:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 ASP 1 271
HIS 1 304
HIS 1 244
 MN  1 601 ( 3.0A)
None
MN  1 602 (-3.3A)
 0.58A 1oe1A-1wao1:
undetectable		 1oe1A-1wao1:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 ASP 1 271
HIS 1 304
HIS 1 244
 MN  1 601 ( 3.0A)
None
MN  1 602 (-3.3A)
 0.57A 1oe3A-1wao1:
undetectable		 1oe3A-1wao1:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 LEU 1 300
ILE 1 344
VAL 1 239
THR 1 229
LEU 1 226
 None
 1.05A 2japA-1wao1:
undetectable		 2japA-1wao1:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 LEU 1 300
ILE 1 344
VAL 1 239
THR 1 229
LEU 1 226
 None
 1.06A 2japB-1wao1:
undetectable		 2japB-1wao1:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 LEU 1 300
ILE 1 344
VAL 1 239
THR 1 229
LEU 1 226
 None
 1.05A 2japC-1wao1:
undetectable		 2japC-1wao1:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 LEU 1 300
ILE 1 344
VAL 1 239
THR 1 229
LEU 1 226
 None
 1.06A 2japD-1wao1:
undetectable		 2japD-1wao1:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 PHE 1 414
LYS 1 347
ILE 1 366
ARG 1 367
GLY 1 353
 None
 1.11A 2lbdA-1wao1:
undetectable		 2lbdA-1wao1:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 7 HIS 1 427
HIS 1 304
ARG 1 275
TYR 1  78
 MN  1 601 (-3.4A)
None
MN  1 602 ( 4.7A)
None
 1.14A 2vmyA-1wao1:
undetectable
2vmyB-1wao1:
undetectable		 2vmyA-1wao1:
23.14
2vmyB-1wao1:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 8 TYR 1  78
HIS 1 427
HIS 1 304
ARG 1 275
 None
MN  1 601 (-3.4A)
None
MN  1 602 ( 4.7A)
 1.13A 2vmyA-1wao1:
undetectable
2vmyB-1wao1:
undetectable		 2vmyA-1wao1:
23.14
2vmyB-1wao1:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 8 GLY 1 354
HIS 1 427
ILE 1 424
ASN 1 269
 None
MN  1 601 (-3.4A)
None
None
 0.87A 2x0pA-1wao1:
undetectable		 2x0pA-1wao1:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 ASP 1 271
HIS 1 304
HIS 1 244
 MN  1 601 ( 3.0A)
None
MN  1 602 (-3.3A)
 0.59A 2xxgA-1wao1:
undetectable		 2xxgA-1wao1:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 ASP 1 271
HIS 1 304
HIS 1 244
 MN  1 601 ( 3.0A)
None
MN  1 602 (-3.3A)
 0.59A 2xxgC-1wao1:
undetectable		 2xxgC-1wao1:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 7 ILE 1 212
LEU 1 204
MET 1 191
LEU 1 250
 None
 0.88A 3adxA-1wao1:
undetectable		 3adxA-1wao1:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 LEU 1 223
VAL 1 334
ARG 1 371
 None
 0.56A 3b0wB-1wao1:
undetectable		 3b0wB-1wao1:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 6 VAL 1 348
VAL 1 445
ILE 1 267
ARG 1 470
 None
 1.08A 3pyyA-1wao1:
undetectable		 3pyyA-1wao1:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 TYR 1  72
LEU 1 493
ARG 1 101
 None
 0.80A 3sufB-1wao1:
undetectable		 3sufB-1wao1:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 6 TYR 1  78
ARG 1 275
ASP 1 388
GLU 1 435
 None
MN  1 602 ( 4.7A)
None
None
 1.37A 4ax8A-1wao1:
undetectable		 4ax8A-1wao1:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 6 ARG 1 275
ASP 1 388
GLN 1 405
GLU 1 435
 MN  1 602 ( 4.7A)
None
None
None
 1.31A 4azvA-1wao1:
undetectable		 4azvA-1wao1:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 6 TYR 1  78
ARG 1 275
ASP 1 388
GLU 1 435
 None
MN  1 602 ( 4.7A)
None
None
 1.41A 4azvA-1wao1:
undetectable		 4azvA-1wao1:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 7 ASP 1 271
ASN 1 303
GLU 1  76
GLU 1 305
 MN  1 601 ( 3.0A)
MN  1 601 (-2.5A)
MN  1 602 ( 4.5A)
None
 1.23A 4fevF-1wao1:
undetectable		 4fevF-1wao1:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 8 ASP 1 271
ASN 1 303
GLU 1  76
GLU 1 305
 MN  1 601 ( 3.0A)
MN  1 601 (-2.5A)
MN  1 602 ( 4.5A)
None
 1.13A 4gkhB-1wao1:
undetectable		 4gkhB-1wao1:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 7 ASP 1 271
ASN 1 303
GLU 1  76
GLU 1 305
 MN  1 601 ( 3.0A)
MN  1 601 (-2.5A)
MN  1 602 ( 4.5A)
None
 1.23A 4gkhG-1wao1:
undetectable		 4gkhG-1wao1:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 8 ASP 1 271
ASN 1 303
GLU 1  76
GLU 1 305
 MN  1 601 ( 3.0A)
MN  1 601 (-2.5A)
MN  1 602 ( 4.5A)
None
 1.04A 4gkiC-1wao1:
undetectable		 4gkiC-1wao1:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 SER 1 277
TYR 1 489
PRO 1 482
 None
 0.92A 4k8cA-1wao1:
undetectable		 4k8cA-1wao1:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 SER 1 277
TYR 1 489
PRO 1 482
 None
 0.93A 4kahA-1wao1:
undetectable		 4kahA-1wao1:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 SER 1 277
TYR 1 489
PRO 1 482
 None
 0.92A 4kahB-1wao1:
undetectable		 4kahB-1wao1:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 SER 1 277
TYR 1 489
PRO 1 482
 None
 0.93A 4kanA-1wao1:
undetectable		 4kanA-1wao1:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 SER 1 277
TYR 1 489
PRO 1 482
 None
 0.92A 4kanB-1wao1:
undetectable		 4kanB-1wao1:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 SER 1 277
TYR 1 489
PRO 1 482
 None
 0.91A 4kbeA-1wao1:
undetectable		 4kbeA-1wao1:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 SER 1 277
TYR 1 489
PRO 1 482
 None
 0.90A 4kbeB-1wao1:
undetectable		 4kbeB-1wao1:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L64_A_C2FA802_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 7 LYS 1 203
TYR 1 210
ARG 1 206
VAL 1 319
 None
 1.18A 4l64A-1wao1:
0.0		 4l64A-1wao1:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 SER 1 277
TYR 1 489
PRO 1 482
 None
 0.94A 4lbgA-1wao1:
undetectable		 4lbgA-1wao1:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 SER 1 277
TYR 1 489
PRO 1 482
 None
 0.94A 4lbgB-1wao1:
undetectable		 4lbgB-1wao1:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 10 SER 1 105
GLY 1  83
THR 1  86
ALA 1  85
ASP 1 118
 None
 1.22A 4qvnV-1wao1:
undetectable
4qvnW-1wao1:
undetectable		 4qvnV-1wao1:
18.84
4qvnW-1wao1:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER 1 105
GLY 1  83
THR 1  86
ALA 1  85
ASP 1 118
 None
 1.21A 4qvpH-1wao1:
undetectable
4qvpI-1wao1:
undetectable		 4qvpH-1wao1:
18.84
4qvpI-1wao1:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER 1 105
GLY 1  83
THR 1  86
ALA 1  85
ASP 1 118
 None
 1.20A 4qvpV-1wao1:
undetectable
4qvpW-1wao1:
undetectable		 4qvpV-1wao1:
18.84
4qvpW-1wao1:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 11 SER 1 105
GLY 1  83
THR 1  86
ALA 1  85
ASP 1 118
 None
 1.22A 4qvqH-1wao1:
undetectable
4qvqI-1wao1:
undetectable		 4qvqH-1wao1:
18.84
4qvqI-1wao1:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 11 SER 1 105
GLY 1  83
THR 1  86
ALA 1  85
ASP 1 118
 None
 1.21A 4qvqV-1wao1:
undetectable
4qvqW-1wao1:
undetectable		 4qvqV-1wao1:
18.84
4qvqW-1wao1:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER 1 105
GLY 1  83
THR 1  86
ALA 1  85
ASP 1 118
 None
 1.24A 4qw1H-1wao1:
undetectable
4qw1I-1wao1:
undetectable		 4qw1H-1wao1:
18.84
4qw1I-1wao1:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER 1 105
GLY 1  83
THR 1  86
ALA 1  85
ASP 1 118
 None
 1.22A 4qw1V-1wao1:
undetectable
4qw1W-1wao1:
undetectable		 4qw1V-1wao1:
18.84
4qw1W-1wao1:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 9 CYH 1 240
SER 1 447
ALA 1 459
LEU 1 256
 None
 0.96A 4xtaA-1wao1:
undetectable		 4xtaA-1wao1:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 6 GLU 1 305
PHE 1 335
GLU 1 318
VAL 1 319
 None
 1.41A 5h4dA-1wao1:
undetectable		 5h4dA-1wao1:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 ARG 1 301
PRO 1 375
ASN 1 308
 None
 1.06A 5jwaA-1wao1:
undetectable
5jwaH-1wao1:
undetectable		 5jwaA-1wao1:
23.05
5jwaH-1wao1:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER 1 105
GLY 1  83
THR 1  86
ALA 1  85
ASP 1 118
 None
 1.18A 5l66H-1wao1:
undetectable
5l66I-1wao1:
undetectable		 5l66H-1wao1:
18.84
5l66I-1wao1:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER 1 105
GLY 1  83
THR 1  86
ALA 1  85
ASP 1 118
 None
 1.18A 5l66V-1wao1:
undetectable
5l66W-1wao1:
undetectable		 5l66V-1wao1:
18.84
5l66W-1wao1:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 GLU 1 305
THR 1 306
ASP 1 271
GLY 1 276
HIS 1 244
 None
None
MN  1 601 ( 3.0A)
None
MN  1 602 (-3.3A)
 1.42A 5m5kB-1wao1:
undetectable		 5m5kB-1wao1:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 4 ASP 1 271
HIS 1 352
HIS 1 427
HIS 1 304
 MN  1 601 ( 3.0A)
MN  1 601 (-3.6A)
MN  1 601 (-3.4A)
None
 1.46A 5ncdD-1wao1:
2.3		 5ncdD-1wao1:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		6 / 12 LEU 1 363
THR 1 362
ILE 1 366
LEU 1 420
LEU 1 415
LEU 1 384
 None
 1.25A 5nfjA-1wao1:
undetectable		 5nfjA-1wao1:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		3 / 3 CYH 1 139
MET 1 107
ASN 1 106
 None
 1.16A 5qh8A-1wao1:
0.0		 5qh8A-1wao1:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		4 / 6 ALA 1  81
SER 1  69
ALA 1 104
SER 1 105
 None
 1.00A 6bocA-1wao1:
undetectable
6bocB-1wao1:
undetectable
6bocC-1wao1:
undetectable
6bocD-1wao1:
undetectable		 6bocA-1wao1:
4.03
6bocB-1wao1:
4.03
6bocC-1wao1:
4.03
6bocD-1wao1:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER 1 403
ASN 1 269
LEU 1 300
ASP 1 383
GLY 1 354
 None
 1.17A 6dwnA-1wao1:
undetectable		 6dwnA-1wao1:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_1
(-)		 1wao SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 10 GLY 1 270
LEU 1 300
SER 1 403
VAL 1 239
CYH 1 240
 None
 1.44A 6gnfC-1wao1:
undetectable		 6gnfC-1wao1:
22.41