SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1waq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1waq GROWTH/DIFFERENTIATI
ON FACTOR 5
(Homo
sapiens) 		3 / 3 GLN A  69
HIS A  65
ARG A 120
 None
 0.91A 1zlqA-1waqA:
undetectable		 1zlqA-1waqA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 1waq GROWTH/DIFFERENTIATI
ON FACTOR 5
(Homo
sapiens) 		3 / 3 THR A  80
PRO A  77
PRO A  81
 None
 0.85A 2d55C-1waqA:
undetectable		 2d55C-1waqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 1waq GROWTH/DIFFERENTIATI
ON FACTOR 5
(Homo
sapiens) 		3 / 3 HIS A  59
SER A  20
ARG A  18
 None
 0.74A 5u63A-1waqA:
undetectable		 5u63A-1waqA:
16.40