SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wb0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 9 TYR A  27
PHE A  58
GLY A  98
ASP A 138
MET A 210
ASP A 213
TRP A 360
 None
 0.96A 1e9lA-1wb0A:
58.0		 1e9lA-1wb0A:
41.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 9 TYR A  27
PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
ASP A 213
 None
 0.80A 1e9lA-1wb0A:
58.0		 1e9lA-1wb0A:
41.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 5 LEU A 158
THR A 157
ARG A 116
VAL A 120
 None
SO4  A 469 (-4.3A)
SO4  A 469 (-3.7A)
None
 1.07A 1ekjF-1wb0A:
undetectable
1ekjG-1wb0A:
undetectable		 1ekjF-1wb0A:
19.55
1ekjG-1wb0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 6 TYR A 195
GLY A 194
GLY A 187
SER A 144
 None
 1.00A 1eswA-1wb0A:
4.6		 1eswA-1wb0A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 GLU A 169
ILE A 124
LEU A 135
GLY A 134
ALA A  59
 None
 1.13A 1hvyA-1wb0A:
undetectable		 1hvyA-1wb0A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 6 LEU A 383
PHE A 342
TYR A 267
VAL A 339
 None
None
None
IPA  A1393 (-3.6A)
 1.08A 1ibgH-1wb0A:
undetectable		 1ibgH-1wb0A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 LEU A 379
LEU A 364
PHE A  58
ALA A  57
TYR A 212
 None
 1.25A 1kt5A-1wb0A:
undetectable		 1kt5A-1wb0A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.82A 1v54P-1wb0A:
0.4
1v54W-1wb0A:
undetectable		 1v54P-1wb0A:
19.69
1v54W-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.84A 1v55C-1wb0A:
undetectable
1v55J-1wb0A:
undetectable		 1v55C-1wb0A:
19.69
1v55J-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.90A 1v55P-1wb0A:
undetectable
1v55W-1wb0A:
undetectable		 1v55P-1wb0A:
19.69
1v55W-1wb0A:
9.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1433_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 11 PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
TYR A 267
TRP A 360
 None
 0.80A 2a3aA-1wb0A:
14.5		 2a3aA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1433_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		10 / 11 TYR A  27
PHE A  58
GLY A  98
TRP A  99
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 360
 None
 0.63A 2a3aA-1wb0A:
14.5		 2a3aA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1435_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		3 / 3 TRP A  99
GLU A 140
TYR A 141
 None
 0.44A 2a3aA-1wb0A:
14.5		 2a3aA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_B_TEPB2433_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 9 PHE A  58
GLY A  98
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 360
 None
 0.48A 2a3aB-1wb0A:
43.6		 2a3aB-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 11 PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
TYR A 267
TRP A 360
 None
 0.84A 2a3bA-1wb0A:
43.5		 2a3bA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 11 TYR A  27
PHE A  58
GLY A  98
GLU A 140
MET A 210
TYR A 212
TRP A 360
 None
 0.82A 2a3bA-1wb0A:
43.5		 2a3bA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 11 TYR A  27
PHE A  58
GLY A  98
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 360
 None
 0.56A 2a3bA-1wb0A:
43.5		 2a3bA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_B_CFFB2435_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 10 PHE A  58
GLY A  98
ASP A 138
GLU A 140
MET A 210
TYR A 212
TRP A 360
 None
 0.98A 2a3bB-1wb0A:
14.5		 2a3bB-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_B_CFFB2435_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 10 PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
TYR A 267
TRP A 360
 None
 0.81A 2a3bB-1wb0A:
14.5		 2a3bB-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_B_CFFB2435_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 10 PHE A  58
GLY A  98
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 360
 None
 0.37A 2a3bB-1wb0A:
14.5		 2a3bB-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 12 TRP A  31
PHE A  58
GLY A  98
ASP A 138
GLU A 140
MET A 210
TYR A 212
TRP A 360
 None
 1.06A 2a3cA-1wb0A:
14.5		 2a3cA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 12 TRP A  31
PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
TYR A 267
TRP A 360
 None
 0.87A 2a3cA-1wb0A:
14.5		 2a3cA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 12 TYR A  27
TRP A  31
PHE A  58
GLY A  98
GLU A 140
MET A 210
TYR A 212
TRP A 360
 None
 0.92A 2a3cA-1wb0A:
14.5		 2a3cA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		9 / 12 TYR A  27
TRP A  31
PHE A  58
GLY A  98
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 360
 None
 0.60A 2a3cA-1wb0A:
14.5		 2a3cA-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 12 TRP A  31
PHE A  58
GLY A  98
ASP A 138
GLU A 140
MET A 210
TYR A 212
TRP A 360
 None
 1.02A 2a3cB-1wb0A:
43.6		 2a3cB-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 12 TRP A  31
PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
TYR A 267
TRP A 360
 None
 0.83A 2a3cB-1wb0A:
43.6		 2a3cB-1wb0A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 12 TRP A  31
PHE A  58
GLY A  98
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 360
 None
 0.43A 2a3cB-1wb0A:
43.6		 2a3cB-1wb0A:
30.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.88A 2dyrP-1wb0A:
0.2
2dyrW-1wb0A:
undetectable		 2dyrP-1wb0A:
19.69
2dyrW-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.94A 2dysC-1wb0A:
undetectable
2dysJ-1wb0A:
undetectable		 2dysC-1wb0A:
19.69
2dysJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.85A 2dysP-1wb0A:
undetectable
2dysW-1wb0A:
undetectable		 2dysP-1wb0A:
19.69
2dysW-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.89A 2eijC-1wb0A:
undetectable
2eijJ-1wb0A:
undetectable		 2eijC-1wb0A:
19.69
2eijJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.81A 2eijP-1wb0A:
undetectable
2eijW-1wb0A:
undetectable		 2eijP-1wb0A:
19.69
2eijW-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.80A 2eikC-1wb0A:
undetectable
2eikJ-1wb0A:
undetectable		 2eikC-1wb0A:
19.69
2eikJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.80A 2eikP-1wb0A:
undetectable
2eikW-1wb0A:
undetectable		 2eikP-1wb0A:
19.69
2eikW-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.82A 2eilC-1wb0A:
undetectable
2eilJ-1wb0A:
undetectable		 2eilC-1wb0A:
19.69
2eilJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.80A 2eilP-1wb0A:
undetectable
2eilW-1wb0A:
undetectable		 2eilP-1wb0A:
19.69
2eilW-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.83A 2eimC-1wb0A:
undetectable
2eimJ-1wb0A:
undetectable		 2eimC-1wb0A:
19.69
2eimJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.89A 2einC-1wb0A:
undetectable
2einJ-1wb0A:
undetectable		 2einC-1wb0A:
19.69
2einJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 VAL A 243
SER A 226
LEU A 349
PHE A 342
 None
 1.05A 2f78A-1wb0A:
undetectable		 2f78A-1wb0A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 PRO A 325
SER A 308
SER A 371
ASP A 338
 None
None
None
IPA  A1393 (-3.5A)
 1.10A 2obvA-1wb0A:
undetectable		 2obvA-1wb0A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		3 / 3 ASP A 330
ASN A 331
THR A 222
 None
 0.70A 2pymB-1wb0A:
undetectable		 2pymB-1wb0A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		3 / 3 ASP A 330
ASN A 331
THR A 222
 None
 0.75A 2q63B-1wb0A:
undetectable		 2q63B-1wb0A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 9 LEU A 137
ILE A  96
GLY A  97
GLY A  98
LEU A  93
 None
 1.09A 2qmmA-1wb0A:
undetectable		 2qmmA-1wb0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 ILE A 327
LEU A 301
GLY A 268
PHE A 336
 None
 0.91A 2tsrB-1wb0A:
undetectable		 2tsrB-1wb0A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 9 TYR A  27
PHE A  58
GLY A  98
ASP A 138
GLU A 140
TYR A 212
TRP A 360
 None
 0.44A 2uy4A-1wb0A:
19.7		 2uy4A-1wb0A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 10 ALA A 183
ASP A 136
LEU A  93
ILE A  55
TYR A 212
 None
 1.17A 2w9sD-1wb0A:
undetectable		 2w9sD-1wb0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 10 ALA A 183
ASP A 136
LEU A  93
ILE A  55
TYR A 212
 None
 1.18A 2w9sF-1wb0A:
undetectable		 2w9sF-1wb0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 11 TYR A  27
PHE A  58
GLY A  98
ASP A 138
GLU A 140
TYR A 212
TRP A 360
 None
 0.69A 2xtkA-1wb0A:
20.6		 2xtkA-1wb0A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		7 / 10 TYR A  27
PHE A  58
GLY A  98
ASP A 138
GLU A 140
TYR A 212
TRP A 360
 None
 0.58A 2xtkB-1wb0A:
20.8		 2xtkB-1wb0A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.93A 2zxwC-1wb0A:
undetectable
2zxwJ-1wb0A:
undetectable		 2zxwC-1wb0A:
19.69
2zxwJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 6 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.91A 2zxwP-1wb0A:
undetectable
2zxwW-1wb0A:
undetectable		 2zxwP-1wb0A:
19.69
2zxwW-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.79A 3ag2P-1wb0A:
undetectable
3ag2W-1wb0A:
undetectable		 3ag2P-1wb0A:
19.69
3ag2W-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.86A 3ag4C-1wb0A:
undetectable
3ag4J-1wb0A:
undetectable		 3ag4C-1wb0A:
19.69
3ag4J-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.80A 3ag4P-1wb0A:
undetectable
3ag4W-1wb0A:
undetectable		 3ag4P-1wb0A:
19.69
3ag4W-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 9 LEU A 137
ILE A  96
GLY A  97
LEU A 180
LEU A  93
 None
 1.02A 3ai9X-1wb0A:
undetectable		 3ai9X-1wb0A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 TRP A  99
GLY A 187
ASP A 213
ARG A 269
 None
 0.80A 3arrA-1wb0A:
41.9		 3arrA-1wb0A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 GLY A 187
ASP A 213
TRP A 218
ARG A 269
 None
 0.55A 3aruA-1wb0A:
41.7		 3aruA-1wb0A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.93A 3asnC-1wb0A:
undetectable
3asnJ-1wb0A:
undetectable		 3asnC-1wb0A:
19.69
3asnJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.94A 3asoC-1wb0A:
undetectable
3asoJ-1wb0A:
undetectable		 3asoC-1wb0A:
19.69
3asoJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_1
(SPERMIDINE SYNTHASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 5 GLN A 374
ASP A 365
ASP A 337
THR A 382
 IPA  A1393 (-3.4A)
None
None
None
 1.21A 3bwcB-1wb0A:
0.3		 3bwcB-1wb0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 ALA A  59
LEU A  66
LEU A 135
LEU A 158
PHE A 106
 None
 1.15A 3fl9G-1wb0A:
undetectable		 3fl9G-1wb0A:
16.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 11 PHE A  58
GLY A  98
TRP A  99
GLU A 140
MET A 210
ASP A 213
TYR A 267
TRP A 360
 None
 0.78A 3g6mA-1wb0A:
44.2		 3g6mA-1wb0A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 11 TYR A  27
PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
TYR A 267
TRP A 360
 None
 0.94A 3g6mA-1wb0A:
44.2		 3g6mA-1wb0A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		9 / 11 TYR A  27
PHE A  58
GLY A  98
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 360
 None
 0.64A 3g6mA-1wb0A:
44.2		 3g6mA-1wb0A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA427_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 5 TRP A  99
TYR A 141
MET A 210
ASP A 213
 None
 0.91A 3g6mA-1wb0A:
44.2		 3g6mA-1wb0A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA427_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 5 TYR A 141
MET A 210
ASP A 213
TRP A 218
 None
 0.55A 3g6mA-1wb0A:
44.2		 3g6mA-1wb0A:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 ASP A 136
TYR A  27
VAL A 207
LEU A 260
 None
 1.10A 3jq7C-1wb0A:
4.1		 3jq7C-1wb0A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 9 ALA A 357
GLY A 263
LEU A 354
LEU A 209
ASN A 208
 None
 1.15A 3wdmA-1wb0A:
undetectable		 3wdmA-1wb0A:
19.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQV_A_GCSA501_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		11 / 11 PHE A  58
GLY A  98
TRP A  99
ASP A 138
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
ARG A 269
TRP A 360
 None
 0.47A 3wqvA-1wb0A:
55.1		 3wqvA-1wb0A:
34.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQW_A_GCSA501_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		11 / 11 PHE A  58
GLY A  98
TRP A  99
ASP A 138
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
ARG A 269
TRP A 360
 None
 0.49A 3wqwA-1wb0A:
55.1		 3wqwA-1wb0A:
34.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.80A 3x2qC-1wb0A:
undetectable
3x2qJ-1wb0A:
undetectable		 3x2qC-1wb0A:
19.69
3x2qJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.79A 3x2qP-1wb0A:
undetectable
3x2qW-1wb0A:
undetectable		 3x2qP-1wb0A:
19.69
3x2qW-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		3 / 3 LYS A  85
LYS A  84
PRO A  88
 SO4  A1396 ( 4.0A)
SO4  A1396 (-2.7A)
None
 1.28A 4dv1L-1wb0A:
undetectable		 4dv1L-1wb0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 PHE A 126
LEU A 135
GLY A 134
PHE A 132
ALA A 182
 None
 1.27A 4eb4A-1wb0A:
undetectable		 4eb4A-1wb0A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 LEU A 178
GLY A 134
PHE A 132
LYS A 175
ALA A 165
 None
 1.26A 4eb4B-1wb0A:
undetectable		 4eb4B-1wb0A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 PHE A 126
LEU A 135
GLY A 134
PHE A 132
ALA A 182
 None
 1.27A 4eb4B-1wb0A:
undetectable		 4eb4B-1wb0A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 LEU A 180
LEU A 135
LEU A  94
ALA A  95
MET A  61
 None
 1.00A 4fn9B-1wb0A:
undetectable		 4fn9B-1wb0A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 PHE A 271
TRP A 333
PRO A 227
GLN A 322
 None
 1.09A 4j7uD-1wb0A:
undetectable		 4j7uD-1wb0A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 PRO A 325
SER A 308
SER A 371
ASP A 338
 None
None
None
IPA  A1393 (-3.5A)
 1.20A 4kttA-1wb0A:
undetectable		 4kttA-1wb0A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 PRO A 325
SER A 308
SER A 371
ASP A 338
 None
None
None
IPA  A1393 (-3.5A)
 1.21A 4kttC-1wb0A:
undetectable		 4kttC-1wb0A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 5 LEU A 127
SER A 122
LEU A 162
LEU A  94
 None
 1.23A 4n09B-1wb0A:
2.4		 4n09B-1wb0A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 5 LEU A 127
SER A 122
LEU A 162
LEU A  94
 None
 1.23A 4n09D-1wb0A:
2.4		 4n09D-1wb0A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 LEU A 180
ALA A 165
PHE A 166
ILE A  96
ILE A 124
 None
 0.80A 4nkxB-1wb0A:
undetectable		 4nkxB-1wb0A:
22.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 7 THR A  29
TRP A  31
ARG A  35
TRP A 360
LEU A 364
 None
 0.45A 4nsbA-1wb0A:
55.1		 4nsbA-1wb0A:
44.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		3 / 3 LEU A 178
LEU A 158
ASN A 121
 None
 0.75A 4otwA-1wb0A:
undetectable		 4otwA-1wb0A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 ASP A 244
LEU A 354
LEU A 262
GLY A 263
PHE A 214
 None
 1.42A 4pfjB-1wb0A:
undetectable		 4pfjB-1wb0A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 ASP A 244
LEU A 354
LEU A 262
GLY A 263
PHE A 214
 None
 1.41A 4pgfB-1wb0A:
undetectable		 4pgfB-1wb0A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.84A 5b1aC-1wb0A:
undetectable
5b1aJ-1wb0A:
undetectable		 5b1aC-1wb0A:
19.69
5b1aJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.80A 5b1aP-1wb0A:
undetectable
5b1aW-1wb0A:
undetectable		 5b1aP-1wb0A:
19.69
5b1aW-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.82A 5b3sC-1wb0A:
undetectable
5b3sJ-1wb0A:
undetectable		 5b3sC-1wb0A:
19.69
5b3sJ-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 ALA A 111
LEU A 137
ILE A  55
GLY A 134
LEU A  66
 None
 1.03A 5fsaA-1wb0A:
undetectable		 5fsaA-1wb0A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		3 / 3 TRP A  99
GLU A 140
ASP A 213
 None
 0.37A 5gqbA-1wb0A:
44.2		 5gqbA-1wb0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		8 / 8 PHE A  58
GLY A  98
TRP A  99
GLU A 140
TYR A 212
ASP A 213
ARG A 269
TRP A 360
 None
 0.48A 5gqbA-1wb0A:
44.2		 5gqbA-1wb0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A  66
GLN A  65
LEU A  94
PHE A 132
 None
 0.78A 5iy5C-1wb0A:
undetectable
5iy5J-1wb0A:
undetectable		 5iy5C-1wb0A:
19.41
5iy5J-1wb0A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 ALA A 183
ASP A 136
LEU A  93
TYR A 212
 None
 0.87A 5uihA-1wb0A:
undetectable		 5uihA-1wb0A:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 ILE A  55
PHE A 106
GLY A 134
LEU A  66
PHE A 101
 None
 1.26A 5v5zA-1wb0A:
undetectable		 5v5zA-1wb0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 SER A 258
GLY A 356
ALA A 357
PHE A 206
SER A 181
 None
 1.21A 5wbvA-1wb0A:
undetectable		 5wbvA-1wb0A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 SER A 258
GLY A 356
ALA A 357
PHE A 206
SER A 181
 None
 1.22A 5wbvB-1wb0A:
undetectable		 5wbvB-1wb0A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 VAL A 243
ASP A 244
LEU A 387
SER A 226
LEU A 383
 None
 1.16A 6ew0F-1wb0A:
undetectable		 6ew0F-1wb0A:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		5 / 12 VAL A 243
ASP A 244
LEU A 387
SER A 226
LEU A 383
 None
 1.16A 6ew0G-1wb0A:
undetectable		 6ew0G-1wb0A:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 PRO A 325
SER A 308
SER A 371
ASP A 338
 None
None
None
IPA  A1393 (-3.5A)
 1.22A 6fbnB-1wb0A:
undetectable		 6fbnB-1wb0A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 8 PRO A 325
SER A 308
SER A 371
ASP A 338
 None
None
None
IPA  A1393 (-3.5A)
 1.17A 6fcbA-1wb0A:
undetectable		 6fcbA-1wb0A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 7 LEU A 228
ASP A 244
GLN A 248
GLN A 351
 None
 1.41A 6g31D-1wb0A:
undetectable		 6g31D-1wb0A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 6 LEU A 228
ASP A 244
GLN A 248
GLN A 351
 None
 1.34A 6g31J-1wb0A:
undetectable		 6g31J-1wb0A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1wb0 CHITOTRIOSIDASE 1
(Homo
sapiens) 		4 / 6 ASP A 213
TYR A 141
GLU A 140
ASP A 138
 None
 1.31A 6mn5A-1wb0A:
0.0		 6mn5A-1wb0A:
11.47