SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wb8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wb8 SUPEROXIDE DISMUTASE
[FE]
(Sulfolobus
solfataricus) 		4 / 6 HIS A  33
ASP A  19
TYR A  16
HIS A  37
 FE  A 212 (-3.3A)
None
None
PMS  A 213 (-4.0A)
 1.50A 2eimA-1wb8A:
undetectable
2eimC-1wb8A:
undetectable		 2eimA-1wb8A:
16.73
2eimC-1wb8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 1wb8 SUPEROXIDE DISMUTASE
[FE]
(Sulfolobus
solfataricus) 		4 / 6 TYR A 187
HIS A  33
HIS A  84
TYR A  87
 None
FE  A 212 (-3.3A)
FE  A 212 (-3.3A)
None
 1.45A 4df2A-1wb8A:
undetectable		 4df2A-1wb8A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wb8 SUPEROXIDE DISMUTASE
[FE]
(Sulfolobus
solfataricus) 		4 / 8 ILE A 165
PRO A 101
VAL A 195
TRP A 197
 None
 1.30A 4f4dB-1wb8A:
undetectable		 4f4dB-1wb8A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1wb8 SUPEROXIDE DISMUTASE
[FE]
(Sulfolobus
solfataricus) 		4 / 8 TYR A 176
VAL A 188
TYR A 187
LEU A 130
 None
 1.05A 4jtrA-1wb8A:
undetectable		 4jtrA-1wb8A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1wb8 SUPEROXIDE DISMUTASE
[FE]
(Sulfolobus
solfataricus) 		3 / 3 LYS A  54
LEU A  60
ARG A  51
 None
 0.91A 5yw0A-1wb8A:
undetectable		 5yw0A-1wb8A:
23.26