SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wc5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1wc5 ADENYLATE CYCLASE
(Arthrospira
platensis) 		5 / 9 VAL A1162
GLY A1119
THR A1085
ILE A1160
THR A1012
 None
 1.29A 1gtnL-1wc5A:
undetectable
1gtnM-1wc5A:
undetectable		 1gtnL-1wc5A:
18.18
1gtnM-1wc5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 1wc5 ADENYLATE CYCLASE
(Arthrospira
platensis) 		4 / 6 MET A1073
ILE A1160
ILE A1195
VAL A1162
 None
 0.85A 4olmA-1wc5A:
undetectable		 4olmA-1wc5A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wc5 ADENYLATE CYCLASE
(Arthrospira
platensis) 		5 / 12 ILE A1120
CYH A1118
GLN A1152
LEU A1090
ILE A1195
 None
None
MG  A2000 ( 4.6A)
None
None
 1.16A 5y2tB-1wc5A:
undetectable		 5y2tB-1wc5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wc5 ADENYLATE CYCLASE
(Arthrospira
platensis) 		5 / 12 LEU A1037
PHE A1058
ILE A1018
GLN A1152
ILE A1160
 None
None
None
MG  A2000 ( 4.6A)
None
 1.17A 5y2tB-1wc5A:
undetectable		 5y2tB-1wc5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wc5 ADENYLATE CYCLASE
(Arthrospira
platensis) 		5 / 12 GLY A1119
CYH A1118
GLN A1152
ILE A1083
MET A1089
 None
None
MG  A2000 ( 4.6A)
None
None
 1.46A 6md4A-1wc5A:
undetectable		 6md4A-1wc5A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wc5 ADENYLATE CYCLASE
(Arthrospira
platensis) 		5 / 12 GLY A1119
CYH A1118
GLN A1152
LEU A1090
ILE A1083
 None
None
MG  A2000 ( 4.6A)
None
None
 1.32A 6md4A-1wc5A:
undetectable		 6md4A-1wc5A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wc5 ADENYLATE CYCLASE
(Arthrospira
platensis) 		5 / 12 GLY A1119
CYH A1118
GLN A1152
LEU A1090
ILE A1195
 None
None
MG  A2000 ( 4.6A)
None
None
 1.38A 6md4A-1wc5A:
undetectable		 6md4A-1wc5A:
18.69