SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wcd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 7 ALA J 366
SER J 103
SER J 105
THR J 107
 None
 0.82A 1dvxA-1wcdJ:
undetectable		 1dvxA-1wcdJ:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 7 ALA J 334
SER J 332
THR J 207
VAL J 205
 None
 0.95A 1dvxB-1wcdJ:
undetectable		 1dvxB-1wcdJ:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYR_A_TOPA407_1
(DIHYDROFOLATE
REDUCTASE)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		5 / 11 ILE J 305
ILE J 261
ILE J 208
ILE J 234
THR J 270
 None
 0.96A 1dyrA-1wcdJ:
undetectable		 1dyrA-1wcdJ:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 8 GLU J 135
LEU J 346
ARG J 204
LEU J 351
 None
 0.80A 1ereE-1wcdJ:
undetectable		 1ereE-1wcdJ:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 8 GLU J 135
LEU J 346
ARG J 204
LEU J 351
 None
 0.81A 1ereF-1wcdJ:
undetectable		 1ereF-1wcdJ:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 8 THR J 412
ASP J 153
ASN J 150
LEU J  18
 None
 1.06A 1lhvA-1wcdJ:
undetectable		 1lhvA-1wcdJ:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 8 THR J 412
ASP J 153
ASN J 150
LEU J  19
 None
 1.09A 1lhvA-1wcdJ:
undetectable		 1lhvA-1wcdJ:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 7 PHE J  82
ALA J  70
ILE J 237
PRO J 304
 None
 1.11A 1oniA-1wcdJ:
undetectable
1oniB-1wcdJ:
undetectable		 1oniA-1wcdJ:
18.18
1oniB-1wcdJ:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 7 ILE J 237
PRO J 304
PHE J  82
ALA J  70
 None
 1.03A 1oniD-1wcdJ:
undetectable
1oniE-1wcdJ:
undetectable		 1oniD-1wcdJ:
18.18
1oniE-1wcdJ:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 6 PHE J  82
ALA J  70
ILE J 237
PRO J 304
 None
 1.04A 1oniH-1wcdJ:
undetectable
1oniI-1wcdJ:
undetectable		 1oniH-1wcdJ:
18.18
1oniI-1wcdJ:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 5 ALA J 232
TYR J 206
ILE J 308
ASP J 235
 None
 0.97A 1upfA-1wcdJ:
undetectable		 1upfA-1wcdJ:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		5 / 7 ALA J 232
TYR J 206
ILE J 308
ILE J 305
ASP J 235
 None
 1.15A 1upfB-1wcdJ:
undetectable		 1upfB-1wcdJ:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 5 ALA J 232
TYR J 206
ILE J 308
ASP J 235
 None
 1.06A 1upfC-1wcdJ:
undetectable		 1upfC-1wcdJ:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		3 / 3 PHE J 371
SER J  43
LEU J  87
 None
 0.79A 2w1bA-1wcdJ:
0.1		 2w1bA-1wcdJ:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 6 ASP J 235
ILE J 305
GLN J 303
TYR J  72
 None
 1.17A 2ya7C-1wcdJ:
undetectable		 2ya7C-1wcdJ:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 5 TYR J 342
ARG J 100
ILE J  28
THR J 398
 None
 1.19A 3dgqA-1wcdJ:
undetectable		 3dgqA-1wcdJ:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		5 / 9 THR J 336
ALA J 334
SER J 332
THR J 207
VAL J 205
 None
 0.83A 3ozkA-1wcdJ:
0.1		 3ozkA-1wcdJ:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 7 ALA J 334
SER J 332
THR J 207
VAL J 205
 None
 0.78A 3ozkB-1wcdJ:
undetectable		 3ozkB-1wcdJ:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 6 GLY J 224
VAL J 313
SER J 315
THR J 226
 None
 1.13A 3tj7C-1wcdJ:
undetectable
3tj7D-1wcdJ:
undetectable		 3tj7C-1wcdJ:
17.89
3tj7D-1wcdJ:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		5 / 10 TYR J 206
ILE J 208
SER J 241
ILE J 308
ALA J 232
 None
 1.29A 3u6tA-1wcdJ:
undetectable		 3u6tA-1wcdJ:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 7 THR J 336
ALA J 334
SER J 332
THR J 207
 None
 0.79A 4d7bA-1wcdJ:
undetectable		 4d7bA-1wcdJ:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 7 THR J 364
ALA J 366
SER J 105
THR J 107
 None
 0.63A 4d7bA-1wcdJ:
undetectable		 4d7bA-1wcdJ:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 7 THR J 336
ALA J 334
THR J 207
VAL J 205
 None
 0.77A 4ik7A-1wcdJ:
undetectable		 4ik7A-1wcdJ:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		5 / 8 THR J 336
ALA J 334
SER J 332
THR J 207
VAL J 205
 None
 0.79A 4ik7B-1wcdJ:
undetectable		 4ik7B-1wcdJ:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 8 THR J 364
ALA J 366
SER J 105
THR J 107
 None
 0.61A 4ik7B-1wcdJ:
undetectable		 4ik7B-1wcdJ:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_A_TOPA202_1
(DIHYDROFOLATE
REDUCTASE)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		5 / 12 ALA J 126
ILE J 124
PHE J  59
LEU J  47
LEU J  86
 None
 1.11A 4km2A-1wcdJ:
undetectable		 4km2A-1wcdJ:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 4 ALA J 366
VAL J 108
GLY J 163
THR J 416
 None
 1.04A 4ubeA-1wcdJ:
undetectable		 4ubeA-1wcdJ:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 4 ASN J 125
SER J  54
ALA J 353
VAL J 352
 None
 1.28A 4x1kC-1wcdJ:
undetectable		 4x1kC-1wcdJ:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1wcd MAJOR STRUCTURAL
PROTEIN VP2
(Infectious
bursal
disease
virus) 		4 / 6 SER J 132
GLY J 340
ASN J 341
ILE J 234
 None
 0.62A 5j4nA-1wcdJ:
undetectable		 5j4nA-1wcdJ:
22.13