SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wcj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1wcj HYPOTHETICAL PROTEIN
TM0487
(Thermotoga
maritima) 		4 / 8 VAL A  18
LEU A  15
MET A  48
VAL A  46
 None
 1.05A 1fduB-1wcjA:
undetectable		 1fduB-1wcjA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 1wcj HYPOTHETICAL PROTEIN
TM0487
(Thermotoga
maritima) 		4 / 5 ALA A  65
ILE A  61
ILE A  19
ASP A  20
 None
 1.08A 2h4jA-1wcjA:
undetectable		 2h4jA-1wcjA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 1wcj HYPOTHETICAL PROTEIN
TM0487
(Thermotoga
maritima) 		4 / 8 ILE A  72
ALA A  65
VAL A  46
VAL A  44
 None
 0.81A 3me6B-1wcjA:
undetectable		 3me6B-1wcjA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1wcj HYPOTHETICAL PROTEIN
TM0487
(Thermotoga
maritima) 		5 / 10 VAL A  18
ASP A  26
LEU A  62
ALA A  65
THR A  83
 None
 1.18A 5m5cE-1wcjA:
undetectable		 5m5cE-1wcjA:
13.66