SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wck'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		5 / 11 LEU A 167
ILE A 174
VAL A 105
LEU A 200
SER A 146
 None
 1.22A 2bxeA-1wckA:
undetectable		 2bxeA-1wckA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A 167
ILE A 174
VAL A 105
LEU A 200
SER A 146
 None
 1.22A 2bxeB-1wckA:
undetectable		 2bxeB-1wckA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		5 / 11 ALA A 140
ILE A 139
PHE A 126
LEU A  87
ILE A 136
 None
 1.11A 2h42A-1wckA:
undetectable		 2h42A-1wckA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		5 / 12 ILE A 208
ILE A 118
SER A 119
PRO A  84
ILE A 209
 None
 1.11A 3cd2A-1wckA:
undetectable		 3cd2A-1wckA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		4 / 8 LEU A 151
ALA A 172
THR A 142
GLY A 195
 None
 0.90A 3ny4A-1wckA:
undetectable		 3ny4A-1wckA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		5 / 11 LEU A  97
LEU A 151
GLY A 149
SER A 146
SER A 205
 None
 1.35A 4zbqA-1wckA:
undetectable		 4zbqA-1wckA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A  97
LEU A 151
GLY A 149
SER A 146
SER A 205
 None
 1.45A 4zbrA-1wckA:
undetectable		 4zbrA-1wckA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		4 / 4 LEU A 198
GLY A 149
SER A 166
SER A 165
 None
 1.18A 5uunA-1wckA:
undetectable		 5uunA-1wckA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		4 / 4 LEU A 198
GLY A 149
SER A 166
SER A 165
 None
 1.12A 5uunB-1wckA:
undetectable		 5uunB-1wckA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		4 / 5 ASN A 108
VAL A 191
LEU A 151
SER A 205
 None
 1.32A 6a7pA-1wckA:
undetectable		 6a7pA-1wckA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 1wck BCLA PROTEIN
(Bacillus
anthracis) 		4 / 5 ASN A 108
VAL A 193
LEU A 198
SER A 205
 None
 1.13A 6a7pA-1wckA:
undetectable		 6a7pA-1wckA:
14.07