SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wcx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		4 / 8 GLU A 183
ARG A 181
LEU A  34
LEU A 175
 None
 0.93A 1cmaA-1wcxA:
undetectable
1cmaB-1wcxA:
undetectable		 1cmaA-1wcxA:
17.31
1cmaB-1wcxA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3002_1
(SERUM ALBUMIN)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 9 GLN A 137
LEU A 138
LEU A 146
ARG A  97
LEU A  62
 None
None
None
GOL  A1001 (-3.6A)
None
 1.47A 1hk1A-1wcxA:
0.0		 1hk1A-1wcxA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		4 / 7 TYR A  49
THR A  66
THR A  67
VAL A  44
 None
 0.94A 1tv8A-1wcxA:
undetectable		 1tv8A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 GLU A 170
GLU A 177
LEU A 198
 None
 0.53A 1v8bA-1wcxA:
6.5		 1v8bA-1wcxA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 GLU A 170
GLU A 177
LEU A 198
 None
 0.53A 1v8bB-1wcxA:
6.5		 1v8bB-1wcxA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		4 / 5 LEU A 187
GLY A 222
PRO A 236
ALA A 218
 None
 0.93A 2aohA-1wcxA:
undetectable		 2aohA-1wcxA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		4 / 8 TYR A  49
THR A  66
THR A  67
VAL A  44
 None
 0.92A 2fb2A-1wcxA:
undetectable		 2fb2A-1wcxA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		4 / 7 TYR A  49
THR A  66
THR A  67
VAL A  44
 None
 0.93A 2fb2B-1wcxA:
undetectable		 2fb2B-1wcxA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		4 / 6 LEU A 105
ALA A  92
LEU A  62
ALA A 135
 None
 0.95A 2vcvK-1wcxA:
undetectable		 2vcvK-1wcxA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 PRO A 162
GLY A  70
TYR A 163
 None
 0.56A 2vouA-1wcxA:
undetectable		 2vouA-1wcxA:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 PRO A 162
GLY A  70
TYR A 163
 None
 0.64A 2vouB-1wcxA:
3.7		 2vouB-1wcxA:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 PRO A 162
GLY A  70
TYR A 163
 None
 0.64A 2vouC-1wcxA:
undetectable		 2vouC-1wcxA:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 9 PHE A  31
GLU A  27
GLY A 246
PHE A  22
GLU A  20
 None
 1.22A 2w98A-1wcxA:
4.4		 2w98A-1wcxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		6 / 9 ALA A  96
VAL A 115
GLY A 116
GLY A 118
LEU A 105
ALA A 102
 None
 1.35A 2z0yA-1wcxA:
undetectable		 2z0yA-1wcxA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		6 / 9 ALA A  96
VAL A 115
GLY A 116
GLY A 118
LEU A 105
ALA A 102
 None
 1.25A 2z0yB-1wcxA:
undetectable		 2z0yB-1wcxA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 12 PHE A 199
LEU A 229
ALA A 211
THR A 214
VAL A 234
 None
 0.95A 3rukA-1wcxA:
undetectable		 3rukA-1wcxA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 12 ALA A 101
GLY A 116
GLY A 118
ASP A 117
ALA A  96
 None
 0.95A 4lg1A-1wcxA:
2.6		 4lg1A-1wcxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 12 ALA A 101
GLY A 116
GLY A 118
ASP A 117
ALA A  96
 None
 0.96A 4lg1C-1wcxA:
undetectable		 4lg1C-1wcxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 184
LEU A 179
VAL A 216
 None
 0.60A 4wq4A-1wcxA:
1.2		 4wq4A-1wcxA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 175
ALA A  12
LEU A 179
LEU A 212
ALA A  14
 None
 1.02A 4z90A-1wcxA:
undetectable
4z90B-1wcxA:
undetectable
4z90C-1wcxA:
undetectable
4z90D-1wcxA:
undetectable
4z90E-1wcxA:
undetectable		 4z90A-1wcxA:
19.17
4z90B-1wcxA:
19.17
4z90C-1wcxA:
19.17
4z90D-1wcxA:
19.17
4z90E-1wcxA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 175
ALA A  14
LEU A 187
LEU A 212
LEU A 208
 None
 1.09A 4z90A-1wcxA:
undetectable
4z90B-1wcxA:
undetectable
4z90C-1wcxA:
undetectable
4z90D-1wcxA:
undetectable
4z90E-1wcxA:
undetectable		 4z90A-1wcxA:
19.17
4z90B-1wcxA:
19.17
4z90C-1wcxA:
19.17
4z90D-1wcxA:
19.17
4z90E-1wcxA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 175
LEU A 179
LEU A 212
ALA A 218
ALA A  14
 None
 1.07A 4z90A-1wcxA:
undetectable
4z90B-1wcxA:
undetectable
4z90C-1wcxA:
undetectable
4z90D-1wcxA:
undetectable
4z90E-1wcxA:
undetectable		 4z90A-1wcxA:
19.17
4z90B-1wcxA:
19.17
4z90C-1wcxA:
19.17
4z90D-1wcxA:
19.17
4z90E-1wcxA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 187
LEU A 212
LEU A 208
LEU A 175
ALA A  14
 None
 1.10A 4z90A-1wcxA:
undetectable
4z90B-1wcxA:
undetectable
4z90C-1wcxA:
undetectable
4z90D-1wcxA:
undetectable
4z90E-1wcxA:
undetectable		 4z90A-1wcxA:
19.17
4z90B-1wcxA:
19.17
4z90C-1wcxA:
19.17
4z90D-1wcxA:
19.17
4z90E-1wcxA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 208
LEU A 175
ALA A  14
LEU A 187
LEU A 212
 None
 1.08A 4z90A-1wcxA:
undetectable
4z90B-1wcxA:
undetectable
4z90C-1wcxA:
undetectable
4z90D-1wcxA:
undetectable
4z90E-1wcxA:
undetectable		 4z90A-1wcxA:
19.17
4z90B-1wcxA:
19.17
4z90C-1wcxA:
19.17
4z90D-1wcxA:
19.17
4z90E-1wcxA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 212
ALA A 218
ALA A  14
LEU A 175
LEU A 179
 None
 1.05A 4z90A-1wcxA:
undetectable
4z90B-1wcxA:
undetectable
4z90C-1wcxA:
undetectable
4z90D-1wcxA:
undetectable
4z90E-1wcxA:
undetectable		 4z90A-1wcxA:
19.17
4z90B-1wcxA:
19.17
4z90C-1wcxA:
19.17
4z90D-1wcxA:
19.17
4z90E-1wcxA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		6 / 9 ALA A  14
LEU A 175
ALA A  12
LEU A 179
LEU A 212
ALA A 218
 None
 1.09A 4z91F-1wcxA:
0.0
4z91G-1wcxA:
undetectable
4z91H-1wcxA:
0.0
4z91I-1wcxA:
undetectable
4z91J-1wcxA:
undetectable		 4z91F-1wcxA:
19.17
4z91G-1wcxA:
19.17
4z91H-1wcxA:
19.17
4z91I-1wcxA:
19.17
4z91J-1wcxA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		6 / 9 LEU A 175
ALA A  12
LEU A 179
LEU A 212
ALA A 218
ALA A  14
 None
 1.10A 4z91F-1wcxA:
0.0
4z91G-1wcxA:
undetectable
4z91H-1wcxA:
0.0
4z91I-1wcxA:
undetectable
4z91J-1wcxA:
undetectable		 4z91F-1wcxA:
19.17
4z91G-1wcxA:
19.17
4z91H-1wcxA:
19.17
4z91I-1wcxA:
19.17
4z91J-1wcxA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		6 / 9 LEU A 198
ALA A  14
LEU A 175
ALA A  12
LEU A 179
LEU A 212
 None
 1.21A 4z91F-1wcxA:
0.0
4z91G-1wcxA:
undetectable
4z91H-1wcxA:
0.0
4z91I-1wcxA:
undetectable
4z91J-1wcxA:
undetectable		 4z91F-1wcxA:
19.17
4z91G-1wcxA:
19.17
4z91H-1wcxA:
19.17
4z91I-1wcxA:
19.17
4z91J-1wcxA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 9 LYS A  28
LEU A  29
LEU A 245
GLY A 246
LEU A 249
 None
 1.08A 5dqfA-1wcxA:
undetectable		 5dqfA-1wcxA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		4 / 7 THR A 242
ASP A 240
TYR A 238
GLY A 251
 None
 1.01A 5hwaA-1wcxA:
undetectable		 5hwaA-1wcxA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 ALA A 188
LEU A 179
LEU A 175
LEU A 229
LEU A 212
 None
 1.14A 5jqbA-1wcxA:
undetectable
5jqbB-1wcxA:
undetectable		 5jqbA-1wcxA:
22.36
5jqbB-1wcxA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.64A 5qgjA-1wcxA:
undetectable		 5qgjA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.64A 5qgmA-1wcxA:
undetectable		 5qgmA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.65A 5qgnA-1wcxA:
undetectable		 5qgnA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.68A 5qguA-1wcxA:
undetectable		 5qguA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.66A 5qgvA-1wcxA:
undetectable		 5qgvA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.65A 5qgwA-1wcxA:
undetectable		 5qgwA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.66A 5qgxA-1wcxA:
undetectable		 5qgxA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.67A 5qgyA-1wcxA:
undetectable		 5qgyA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.66A 5qgzA-1wcxA:
undetectable		 5qgzA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.68A 5qh1A-1wcxA:
undetectable		 5qh1A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.67A 5qh2A-1wcxA:
undetectable		 5qh2A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.66A 5qh3A-1wcxA:
undetectable		 5qh3A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.67A 5qh4A-1wcxA:
undetectable		 5qh4A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.64A 5qh5A-1wcxA:
undetectable		 5qh5A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.62A 5qh6A-1wcxA:
undetectable		 5qh6A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.65A 5qh7A-1wcxA:
undetectable		 5qh7A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.63A 5qh9A-1wcxA:
undetectable		 5qh9A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.66A 5qhaA-1wcxA:
undetectable		 5qhaA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.70A 5qhcA-1wcxA:
undetectable		 5qhcA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.69A 5qheA-1wcxA:
undetectable		 5qheA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.62A 5qhfA-1wcxA:
undetectable		 5qhfA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.67A 5qhgA-1wcxA:
undetectable		 5qhgA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 133
VAL A  60
GLN A  58
 None
 0.65A 5qhhA-1wcxA:
undetectable		 5qhhA-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 GLU A 176
LEU A 179
ARG A 215
 None
 0.82A 6d8fA-1wcxA:
0.0		 6d8fA-1wcxA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 1wcx UROPORPHYRINOGEN III
SYNTHASE
(Thermus
thermophilus) 		4 / 8 LYS A  28
LEU A 245
GLY A 246
LEU A 249
 None
 0.79A 6mdqA-1wcxA:
undetectable		 6mdqA-1wcxA:
14.94