SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1wdj HYPOTHETICAL PROTEIN
TT1808
(Thermus
thermophilus) 		4 / 7 VAL A 154
LEU A 183
VAL A 167
LEU A 172
 None
 0.78A 1cqpA-1wdjA:
undetectable
1cqpB-1wdjA:
undetectable		 1cqpA-1wdjA:
20.87
1cqpB-1wdjA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 1wdj HYPOTHETICAL PROTEIN
TT1808
(Thermus
thermophilus) 		4 / 6 SER A  81
PHE A  77
ASP A  79
GLU A  29
 None
 0.89A 2vn1B-1wdjA:
undetectable		 2vn1B-1wdjA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 1wdj HYPOTHETICAL PROTEIN
TT1808
(Thermus
thermophilus) 		4 / 6 LEU A  52
PHE A 179
ALA A 180
LEU A 183
 None
 1.00A 3t3zA-1wdjA:
undetectable		 3t3zA-1wdjA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 1wdj HYPOTHETICAL PROTEIN
TT1808
(Thermus
thermophilus) 		4 / 6 LEU A  52
PHE A 179
ALA A 180
LEU A 183
 None
 0.98A 3t3zD-1wdjA:
undetectable		 3t3zD-1wdjA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 1wdj HYPOTHETICAL PROTEIN
TT1808
(Thermus
thermophilus) 		3 / 3 ARG A  18
LEU A  22
GLU A  21
 None
 0.77A 4l3gF-1wdjA:
undetectable		 4l3gF-1wdjA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 1wdj HYPOTHETICAL PROTEIN
TT1808
(Thermus
thermophilus) 		4 / 5 ARG A  48
GLY A  46
GLU A  44
SER A  84
 None
 1.26A 4z3oA-1wdjA:
undetectable
4z3oB-1wdjA:
undetectable		 4z3oA-1wdjA:
14.54
4z3oB-1wdjA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1wdj HYPOTHETICAL PROTEIN
TT1808
(Thermus
thermophilus) 		4 / 5 SER A  84
ARG A  48
GLY A  46
GLU A  44
 None
 1.01A 5cdqA-1wdjA:
undetectable
5cdqB-1wdjA:
undetectable
5cdqC-1wdjA:
undetectable		 5cdqA-1wdjA:
18.53
5cdqB-1wdjA:
23.85
5cdqC-1wdjA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1wdj HYPOTHETICAL PROTEIN
TT1808
(Thermus
thermophilus) 		4 / 5 SER A  84
ARG A  48
GLY A  46
GLU A  44
 None
 1.01A 5cdqR-1wdjA:
undetectable
5cdqS-1wdjA:
undetectable
5cdqT-1wdjA:
undetectable		 5cdqR-1wdjA:
18.53
5cdqS-1wdjA:
23.85
5cdqT-1wdjA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wdj HYPOTHETICAL PROTEIN
TT1808
(Thermus
thermophilus) 		3 / 3 ARG A 156
LEU A 141
PHE A  89
 None
 0.81A 6nknP-1wdjA:
undetectable		 6nknP-1wdjA:
21.19