SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		3 / 3 ASP A  96
VAL A 111
PRO A 101
 None
 0.77A 2avvA-1wduA:
undetectable		 2avvA-1wduA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		3 / 3 ASP A 198
VAL A 210
PRO A 129
 None
 0.77A 2avvA-1wduA:
undetectable		 2avvA-1wduA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		5 / 12 TYR A 125
ALA A 158
VAL A 212
THR A 180
MET A 178
 None
 1.43A 2qo4A-1wduA:
undetectable		 2qo4A-1wduA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		5 / 12 GLY A  67
ALA A  52
ILE A  54
LEU A 232
ILE A  42
 None
 0.99A 3adxB-1wduA:
undetectable		 3adxB-1wduA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		3 / 3 LEU A  95
GLU A 119
ILE A 120
 None
 0.58A 3czhA-1wduA:
undetectable		 3czhA-1wduA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		4 / 8 ILE A 140
PHE A 214
THR A 216
VAL A 143
 None
 0.83A 3me6B-1wduA:
undetectable		 3me6B-1wduA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		5 / 12 ILE A  88
TYR A 125
LEU A  53
VAL A  25
ILE A 223
 None
 1.10A 4g1bD-1wduA:
undetectable		 4g1bD-1wduA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		3 / 3 ASP A 211
ARG A 173
THR A 196
 None
 0.87A 4i13A-1wduA:
undetectable		 4i13A-1wduA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		3 / 3 ASP A 211
ARG A 173
THR A 196
 None
 0.85A 4p3rA-1wduA:
undetectable		 4p3rA-1wduA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		5 / 11 GLY A  67
ALA A  52
ILE A  54
LEU A 232
ILE A  42
 None
 1.08A 4xumB-1wduA:
undetectable		 4xumB-1wduA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		5 / 12 VAL A 233
ILE A  54
LEU A 122
LEU A  26
ALA A  50
 None
 1.21A 5fctB-1wduA:
0.6		 5fctB-1wduA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		4 / 4 LEU A 137
LEU A 181
GLY A 179
GLU A 183
 None
 1.22A 5hhjA-1wduA:
undetectable		 5hhjA-1wduA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		5 / 12 ALA A  52
VAL A  25
GLY A 156
GLU A  56
ALA A 158
 None
None
None
PO4  A 249 (-4.0A)
None
 1.08A 5n5dA-1wduA:
2.7		 5n5dA-1wduA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		4 / 5 ASN A  29
ASP A 157
ASN A 159
ASP A 130
 PO4  A 249 (-3.7A)
PO4  A 249 (-3.7A)
PO4  A 249 (-3.3A)
None
 1.33A 5vooE-1wduA:
undetectable		 5vooE-1wduA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		4 / 7 THR A 216
LEU A 152
ILE A 120
THR A 121
 None
 0.98A 5zsfA-1wduA:
0.0
5zsfB-1wduA:
0.0		 5zsfA-1wduA:
15.11
5zsfB-1wduA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1wdu TRAS1 ORF2P
(Bombyx
mori) 		4 / 5 LEU A 137
ILE A 223
MET A 178
GLY A 174
 None
 1.00A 6hd6A-1wduA:
undetectable		 6hd6A-1wduA:
16.93