SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wdv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		4 / 6 ASP A  50
LEU A  49
VAL A  48
ILE A  47
 None
 0.90A 1s9qA-1wdvA:
undetectable		 1s9qA-1wdvA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		4 / 8 MET A  71
ARG A  80
ALA A  82
LEU A  81
 None
 0.91A 2o01A-1wdvA:
undetectable		 2o01A-1wdvA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		4 / 7 GLU A  73
VAL A 150
VAL A  79
ALA A  75
 None
 0.97A 3kp6B-1wdvA:
undetectable		 3kp6B-1wdvA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		5 / 12 VAL A 101
LEU A 139
VAL A  98
GLY A 126
LEU A 132
 None
 1.00A 3pghD-1wdvA:
undetectable		 3pghD-1wdvA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		3 / 3 PRO A  24
THR A  25
LEU A 131
 None
 0.56A 3ttrA-1wdvA:
undetectable		 3ttrA-1wdvA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		5 / 10 MET A  71
ARG A  80
ALA A  82
LEU A  81
ALA A  31
 None
 1.05A 4fe1A-1wdvA:
undetectable
4fe1J-1wdvA:
undetectable		 4fe1A-1wdvA:
12.73
4fe1J-1wdvA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		5 / 11 MET A  71
ARG A  80
ALA A  82
LEU A  81
ALA A  31
 None
 1.17A 4l6v1-1wdvA:
undetectable
4l6v6-1wdvA:
undetectable		 4l6v1-1wdvA:
13.22
4l6v6-1wdvA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		4 / 8 MET A  71
ARG A  80
ALA A  82
LEU A  81
 None
 1.01A 4rkuA-1wdvA:
undetectable
4rkuJ-1wdvA:
undetectable		 4rkuA-1wdvA:
12.64
4rkuJ-1wdvA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		4 / 7 MET A  71
ARG A  80
ALA A  82
LEU A  81
 None
 1.02A 4xk8A-1wdvA:
undetectable		 4xk8A-1wdvA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		3 / 3 ARG A  17
TYR A 122
GLU A 133
 None
 0.71A 4zzbE-1wdvA:
undetectable		 4zzbE-1wdvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		5 / 12 VAL A 101
LEU A 139
VAL A  98
GLY A 126
LEU A 132
 None
 1.01A 5jvzA-1wdvA:
undetectable		 5jvzA-1wdvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		5 / 12 GLY A 126
LEU A 132
VAL A 101
ALA A 102
LEU A 103
 None
 0.97A 5kpcA-1wdvA:
undetectable		 5kpcA-1wdvA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1wdv HYPOTHETICAL PROTEIN
APE2540
(Aeropyrum
pernix) 		5 / 9 GLY A 126
VAL A   5
GLU A   6
GLY A  97
PRO A  99
 None
 1.24A 5zniA-1wdvA:
undetectable		 5zniA-1wdvA:
20.39