SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1we0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1we0 ALKYL HYDROPEROXIDE
REDUCTASE C
(Amphibacillus
xylanus) 		4 / 8 SER A  72
SER A  86
SER A  91
ILE A  92
 None
 0.91A 1gm7A-1we0A:
undetectable
1gm7B-1we0A:
undetectable		 1gm7A-1we0A:
20.81
1gm7B-1we0A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1we0 ALKYL HYDROPEROXIDE
REDUCTASE C
(Amphibacillus
xylanus) 		4 / 6 LEU A 148
VAL A 152
LYS A 153
ILE A 124
 None
 0.66A 2piwA-1we0A:
undetectable		 2piwA-1we0A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 1we0 ALKYL HYDROPEROXIDE
REDUCTASE C
(Amphibacillus
xylanus) 		4 / 8 TYR A  94
GLN A  16
VAL A  89
HIS A  83
 None
 1.17A 3b9lA-1we0A:
undetectable		 3b9lA-1we0A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1we0 ALKYL HYDROPEROXIDE
REDUCTASE C
(Amphibacillus
xylanus) 		5 / 12 LEU A  29
VAL A   7
ILE A 131
LEU A  61
TYR A  58
 None
 1.14A 3g9eA-1we0A:
undetectable		 3g9eA-1we0A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1we0 ALKYL HYDROPEROXIDE
REDUCTASE C
(Amphibacillus
xylanus) 		5 / 11 SER A 105
ILE A  97
VAL A  36
PHE A 123
VAL A   7
 None
 1.08A 3w67A-1we0A:
undetectable		 3w67A-1we0A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1we0 ALKYL HYDROPEROXIDE
REDUCTASE C
(Amphibacillus
xylanus) 		4 / 7 ALA A  41
ASP A  42
ILE A 104
THR A 115
 None
 0.88A 4eyrA-1we0A:
undetectable		 4eyrA-1we0A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 1we0 ALKYL HYDROPEROXIDE
REDUCTASE C
(Amphibacillus
xylanus) 		5 / 12 LEU A   2
PHE A 123
GLY A 121
ASP A 119
ILE A 141
 None
 1.35A 6dwnA-1we0A:
undetectable		 6dwnA-1we0A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1we0 ALKYL HYDROPEROXIDE
REDUCTASE C
(Amphibacillus
xylanus) 		3 / 3 VAL A  24
GLU A  23
ILE A  97
 None
 0.63A 6f7lB-1we0A:
undetectable		 6f7lB-1we0A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 1we0 ALKYL HYDROPEROXIDE
REDUCTASE C
(Amphibacillus
xylanus) 		4 / 8 PHE A  10
VAL A  36
SER A  34
TYR A  69
 None
 0.70A 6huoC-1we0A:
undetectable
6huoD-1we0A:
undetectable		 6huoC-1we0A:
16.40
6huoD-1we0A:
18.03