SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1we1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A52_B_ESTB2_1 (ESTROGEN RECEPTOR)	1we1	HEME OXYGENASE 1 (Synechocystis sp. PCC 6803)	5 / 10	MET A 175 GLU A 118 LEU A 119 LEU A 120 LEU A 9	None	1.44A	1a52B-1we1A: 2.7	1a52B-1we1A: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_B_DESB459_2 (ESTROGEN-RELATED RECEPTOR GAMMA)	1we1	HEME OXYGENASE 1 (Synechocystis sp. PCC 6803)	3 / 3	LEU A 120 HIS A 63 ILE A 65	None	0.69A	1s9pB-1we1A: 0.0	1s9pB-1we1A: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U18_B_HSMB402_1 (NITROPHORIN 1)	1we1	HEME OXYGENASE 1 (Synechocystis sp. PCC 6803)	4 / 5	ASP A 190 GLU A 186 THR A 13 LEU A 9	None	1.16A	1u18B-1we1A: undetectable	1u18B-1we1A: 21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJB_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	1we1	HEME OXYGENASE 1 (Synechocystis sp. PCC 6803)	4 / 8	LEU A 74 LEU A 129 ILE A 65 MET A 57	None HEM A 300 ( 4.4A) None IPA A1005 (-4.8A)	1.01A	5ljbA-1we1A: undetectable	5ljbA-1we1A: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA608_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	1we1	HEME OXYGENASE 1 (Synechocystis sp. PCC 6803)	3 / 3	GLY A 151 THR A 153 GLU A 157	None	0.65A	6b58A-1we1A: undetectable	6b58A-1we1A: 15.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A52_B_ESTB2_1","ESTROGEN RECEPTOR","1we1","HEME OXYGENASE 1","Synechocystis sp. PCC 6803",5,"MET A 175;GLU A 118;LEU A 119;LEU A 120;LEU A   9","None","1.44A","1a52B-1we1A:2.7","1a52B-1we1A:21.32"],["1S9P_B_DESB459_2","ESTROGEN-RELATED RECEPTOR GAMMA","1we1","HEME OXYGENASE 1","Synechocystis sp. PCC 6803",3,"LEU A 120;HIS A  63;ILE A  65","None","0.69A","1s9pB-1we1A:0.0","1s9pB-1we1A:22.14"],["1U18_B_HSMB402_1","NITROPHORIN 1","1we1","HEME OXYGENASE 1","Synechocystis sp. PCC 6803",4,"ASP A 190;GLU A 186;THR A  13;LEU A   9","None","1.16A","1u18B-1we1A:undetectable","1u18B-1we1A:21.81"],["5LJB_A_RTLA201_1","RETINOL-BINDING PROTEIN 1","1we1","HEME OXYGENASE 1","Synechocystis sp. PCC 6803",4,"LEU A  74;LEU A 129;ILE A  65;MET A  57","None;HEM A 300 ( 4.4A);None;IPA A1005 (-4.8A)","1.01A","5ljbA-1we1A:undetectable","5ljbA-1we1A:18.33"],["6B58_A_ACTA608_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","1we1","HEME OXYGENASE 1","Synechocystis sp. PCC 6803",3,"GLY A 151;THR A 153;GLU A 157","None","0.65A","6b58A-1we1A:undetectable","6b58A-1we1A:15.58"]]