SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1we5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 GLU A 167
TYR A 194
PHE A 169
 None
 0.66A 1eqbB-1we5A:
undetectable		 1eqbB-1we5A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 GLU A 167
TYR A 194
PHE A 169
 None
 0.66A 1eqbA-1we5A:
undetectable		 1eqbA-1we5A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 GLU A 167
TYR A 194
PHE A 169
 None
 0.67A 1eqbD-1we5A:
undetectable		 1eqbD-1we5A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 GLU A 167
TYR A 194
PHE A 169
 None
 0.67A 1eqbC-1we5A:
undetectable		 1eqbC-1we5A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 12 ILE A 197
LEU A 251
HIS A 439
LEU A 209
ILE A 242
 None
 1.21A 1fmlB-1we5A:
undetectable		 1fmlB-1we5A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 8 ILE A 197
PHE A 218
LEU A 209
VAL A 470
 None
 0.90A 1fslA-1we5A:
undetectable		 1fslA-1we5A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 12 LEU A 402
LEU A 405
VAL A 406
VAL A 448
LEU A 463
 None
 1.27A 1ie9A-1we5A:
undetectable		 1ie9A-1we5A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 7 VAL A 725
LEU A 736
LEU A 759
ALA A 753
 None
 0.70A 1j8uA-1we5A:
undetectable		 1j8uA-1we5A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 4 SER A 132
VAL A 228
PHE A 122
VAL A  67
 None
 1.50A 1o86A-1we5A:
undetectable		 1o86A-1we5A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 8 GLY A 501
GLY A 497
GLY A 496
LEU A 498
SER A 503
 None
 1.21A 1qzzA-1we5A:
undetectable		 1qzzA-1we5A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 12 SER A 431
ASP A 432
ASP A 429
ILE A 421
THR A 390
 None
 1.35A 1s14A-1we5A:
undetectable		 1s14A-1we5A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 8 LEU A 123
LEU A 154
VAL A  67
GLY A  66
 None
 0.70A 2po5A-1we5A:
undetectable		 2po5A-1we5A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 8 LEU A 123
LEU A 154
VAL A  67
GLY A  66
 None
 0.79A 2po5B-1we5A:
2.2		 2po5B-1we5A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 7 GLY A 187
THR A 188
CYH A 483
PHE A 515
 None
 1.15A 2qx4A-1we5A:
undetectable
2qx4B-1we5A:
undetectable		 2qx4A-1we5A:
14.88
2qx4B-1we5A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 11 TYR A 662
ASP A 642
PHE A 628
GLN A 627
VAL A 626
 None
 1.23A 2vcdA-1we5A:
undetectable		 2vcdA-1we5A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 6 ASP A 291
ILE A 290
LEU A 340
GLU A 283
 None
 1.03A 2ya7A-1we5A:
undetectable		 2ya7A-1we5A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 6 ASP A 291
ILE A 290
LEU A 340
GLU A 283
 None
 1.01A 2ya7B-1we5A:
0.7		 2ya7B-1we5A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 6 ASP A 291
ILE A 290
LEU A 340
GLU A 283
 None
 1.01A 2ya7D-1we5A:
2.2		 2ya7D-1we5A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 6 TYR A 206
THR A 130
VAL A 228
VAL A 210
 None
 0.99A 2z97A-1we5A:
undetectable		 2z97A-1we5A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 GLU A 180
VAL A 216
CYH A 215
 None
 0.95A 3fbxA-1we5A:
0.0		 3fbxA-1we5A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 6 LEU A 156
GLU A 160
ASN A 203
SER A 226
 None
 1.25A 3i9jB-1we5A:
undetectable		 3i9jB-1we5A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 12 ILE A  86
PHE A  57
ILE A  94
VAL A  92
VAL A  90
 None
 1.14A 3iw1A-1we5A:
undetectable		 3iw1A-1we5A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 12 SER A 431
ASP A 432
ASP A 429
ILE A 421
THR A 390
 None
 1.35A 3lpsA-1we5A:
undetectable		 3lpsA-1we5A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 8 TYR A 200
SER A 132
LEU A 154
ASP A 155
 None
 1.10A 3lsfH-1we5A:
undetectable		 3lsfH-1we5A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 THR A 585
ASP A 612
GLU A 702
 None
 0.76A 3qowA-1we5A:
undetectable		 3qowA-1we5A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA598_0
(LACTOPEROXIDASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 5 ARG A  56
GLU A 238
PHE A 240
PRO A  60
 None
 1.47A 3r4xA-1we5A:
0.0		 3r4xA-1we5A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 8 TYR A 349
ASN A 347
ILE A 421
PHE A 389
 None
 0.99A 3rqwI-1we5A:
undetectable
3rqwJ-1we5A:
undetectable		 3rqwI-1we5A:
17.16
3rqwJ-1we5A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 5 ASP A 602
GLU A 160
GLY A 159
TYR A 603
 None
 1.26A 3w9tE-1we5A:
undetectable		 3w9tE-1we5A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 LYS A 353
PRO A 355
LYS A 311
 None
 0.89A 4dr5L-1we5A:
0.0		 4dr5L-1we5A:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 LYS A 353
PRO A 355
LYS A 311
 None
 0.97A 4dr6L-1we5A:
0.0		 4dr6L-1we5A:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 LYS A 353
PRO A 355
LYS A 311
 None
 0.73A 4duzL-1we5A:
0.0		 4duzL-1we5A:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 LYS A 353
PRO A 355
LYS A 311
 None
 1.05A 4dv7L-1we5A:
undetectable		 4dv7L-1we5A:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 PHE A 230
TYR A 206
TYR A 200
 None
 0.86A 4ffwA-1we5A:
undetectable		 4ffwA-1we5A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 LYS A 338
LEU A 335
ALA A 337
 None
 0.73A 4ikiA-1we5A:
undetectable		 4ikiA-1we5A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_F_ACTF701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 4 PHE A  53
HIS A  71
GLY A 138
ILE A  17
 None
 1.48A 4k50E-1we5A:
0.0		 4k50E-1we5A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_M_ACTM503_0
(RNA POLYMERASE
3D-POL)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 4 PHE A  53
HIS A  71
GLY A 138
ILE A  17
 None
 1.50A 4k50M-1we5A:
0.0		 4k50M-1we5A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 8 VAL A 547
SER A 288
GLY A 292
ALA A 550
 None
 0.86A 4m48A-1we5A:
undetectable		 4m48A-1we5A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 12 GLY A 497
GLY A 496
THR A 188
LEU A 502
MET A 588
 None
 1.13A 4pghD-1we5A:
undetectable		 4pghD-1we5A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 11 SER A 431
ASP A 432
ASP A 429
ILE A 421
THR A 390
 None
 1.34A 4urnB-1we5A:
undetectable		 4urnB-1we5A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 11 SER A 431
ASP A 432
ASP A 429
ILE A 421
THR A 390
 None
 1.36A 4urnC-1we5A:
undetectable		 4urnC-1we5A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 5 SER A 268
ALA A 266
HIS A 536
MET A 570
 None
 1.05A 5dzkb-1we5A:
undetectable
5dzkp-1we5A:
undetectable		 5dzkb-1we5A:
13.64
5dzkp-1we5A:
0.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 6 SER A 268
ALA A 266
HIS A 536
MET A 570
 None
 1.05A 5dzkB-1we5A:
undetectable
5dzkP-1we5A:
undetectable		 5dzkB-1we5A:
13.64
5dzkP-1we5A:
0.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 5 SER A 268
ALA A 266
HIS A 536
MET A 570
 None
 1.06A 5dzkc-1we5A:
undetectable
5dzkq-1we5A:
undetectable		 5dzkc-1we5A:
13.64
5dzkq-1we5A:
0.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 7 SER A 268
ALA A 266
HIS A 536
MET A 570
 None
 1.07A 5dzkD-1we5A:
undetectable
5dzkR-1we5A:
undetectable		 5dzkD-1we5A:
13.64
5dzkR-1we5A:
0.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 6 SER A 268
HIS A 536
MET A 570
LEU A 263
 None
 1.13A 5dzke-1we5A:
undetectable
5dzks-1we5A:
undetectable		 5dzke-1we5A:
13.64
5dzks-1we5A:
0.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 5 SER A 268
ALA A 266
HIS A 536
MET A 570
 None
 1.06A 5dzkf-1we5A:
undetectable
5dzkt-1we5A:
undetectable		 5dzkf-1we5A:
13.64
5dzkt-1we5A:
0.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 6 SER A 268
ALA A 266
HIS A 536
MET A 570
 None
 1.06A 5dzkg-1we5A:
undetectable
5dzku-1we5A:
undetectable		 5dzkg-1we5A:
13.64
5dzku-1we5A:
0.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 PRO A 678
LEU A 340
SER A 268
 None
 0.73A 5fsaB-1we5A:
undetectable		 5fsaB-1we5A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		4 / 8 GLN A 757
LEU A 669
LEU A 671
THR A 735
 None
 1.16A 5hs6A-1we5A:
undetectable		 5hs6A-1we5A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 GLY A   6
GLN A  11
LYS A 224
 None
 0.95A 5imsB-1we5A:
1.1		 5imsB-1we5A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UPD_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD3)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 11 GLY A 159
ASN A 175
ASN A 203
TYR A 163
CYH A 601
 None
 1.44A 5updA-1we5A:
undetectable		 5updA-1we5A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 LEU A 123
THR A  97
ASN A  96
 None
 0.69A 6baaE-1we5A:
undetectable		 6baaE-1we5A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 LEU A 123
THR A  97
ASN A  96
 None
 0.69A 6baaF-1we5A:
undetectable		 6baaF-1we5A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 LEU A 123
THR A  97
ASN A  96
 None
 0.70A 6baaG-1we5A:
undetectable		 6baaG-1we5A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		3 / 3 LEU A 123
THR A  97
ASN A  96
 None
 0.69A 6baaH-1we5A:
undetectable		 6baaH-1we5A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CEN_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD3)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 11 GLY A 159
ASN A 175
ASN A 203
TYR A 163
CYH A 601
 None
 1.43A 6cenA-1we5A:
undetectable		 6cenA-1we5A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 1we5 PUTATIVE FAMILY 31
GLUCOSIDASE YICI
(Escherichia
coli) 		5 / 12 VAL A 462
VAL A 477
ASP A 707
PHE A 269
TYR A 574
 None
 1.30A 6mxtA-1we5A:
0.0		 6mxtA-1we5A:
20.61