SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1we7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 1we7 SF3A1 PROTEIN
(Mus
musculus) 		4 / 6 HIS A  66
ILE A  65
ALA A 105
VAL A  30
 None
 1.04A 1hk1A-1we7A:
undetectable		 1hk1A-1we7A:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 1we7 SF3A1 PROTEIN
(Mus
musculus) 		5 / 12 GLY A  47
THR A  69
ILE A  65
GLN A  31
LEU A 104
 None
 1.20A 4o5fA-1we7A:
undetectable
4o5fB-1we7A:
undetectable		 4o5fA-1we7A:
16.29
4o5fB-1we7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1we7 SF3A1 PROTEIN
(Mus
musculus) 		5 / 12 GLN A  31
LEU A 104
GLY A  47
THR A  69
ILE A  65
 None
 1.20A 4o5fA-1we7A:
undetectable
4o5fB-1we7A:
undetectable		 4o5fA-1we7A:
16.29
4o5fB-1we7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 1we7 SF3A1 PROTEIN
(Mus
musculus) 		5 / 12 GLY A  47
THR A  69
ILE A  65
GLN A  31
LEU A 104
 None
 1.18A 5b8hA-1we7A:
undetectable
5b8hB-1we7A:
undetectable		 5b8hA-1we7A:
15.77
5b8hB-1we7A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1we7 SF3A1 PROTEIN
(Mus
musculus) 		5 / 12 GLN A  31
LEU A 104
GLY A  47
THR A  69
ILE A  65
 None
 1.19A 5b8hA-1we7A:
undetectable
5b8hB-1we7A:
undetectable		 5b8hA-1we7A:
15.77
5b8hB-1we7A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1we7 SF3A1 PROTEIN
(Mus
musculus) 		3 / 3 GLY A  74
ASP A  87
ILE A  85
 None
 0.61A 6dgxB-1we7A:
undetectable		 6dgxB-1we7A:
24.75