SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wf8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 1wf8 NEURABIN-I
(Homo
sapiens) 		5 / 11 LEU A  22
GLY A  23
ILE A  24
SER A  25
ILE A  26
 None
 0.63A 2kawA-1wf8A:
10.7		 2kawA-1wf8A:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1wf8 NEURABIN-I
(Homo
sapiens) 		5 / 12 GLY A  41
GLY A  28
ILE A  27
GLU A  38
VAL A  31
 None
 0.94A 3o7wA-1wf8A:
undetectable		 3o7wA-1wf8A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 1wf8 NEURABIN-I
(Homo
sapiens) 		4 / 4 LEU A   8
GLY A  97
LEU A  10
GLU A   9
 None
 0.99A 3tgvB-1wf8A:
undetectable		 3tgvB-1wf8A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1wf8 NEURABIN-I
(Homo
sapiens) 		5 / 10 GLY A  28
GLY A  30
VAL A  74
LEU A  73
ALA A  81
 None
 1.19A 5o96E-1wf8A:
undetectable
5o96F-1wf8A:
undetectable		 5o96E-1wf8A:
20.81
5o96F-1wf8A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 1wf8 NEURABIN-I
(Homo
sapiens) 		6 / 12 PHE A  94
ILE A  59
ILE A  24
ILE A  26
LEU A  22
VAL A  68
 None
 1.42A 5uvmB-1wf8A:
undetectable		 5uvmB-1wf8A:
25.00