SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wfm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 1wfm SYNAPTOTAGMIN XIII
(Homo
sapiens) 		5 / 10 LEU A 111
VAL A  48
VAL A  30
TYR A  17
LEU A 130
 None
 1.38A 1fkoA-1wfmA:
undetectable		 1fkoA-1wfmA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 1wfm SYNAPTOTAGMIN XIII
(Homo
sapiens) 		3 / 3 ALA A  35
THR A  37
CYH A  46
 None
 0.52A 3e4eA-1wfmA:
undetectable		 3e4eA-1wfmA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 1wfm SYNAPTOTAGMIN XIII
(Homo
sapiens) 		3 / 3 ALA A  35
THR A  37
CYH A  46
 None
 0.44A 3e4eB-1wfmA:
undetectable		 3e4eB-1wfmA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1wfm SYNAPTOTAGMIN XIII
(Homo
sapiens) 		4 / 8 ALA A  90
GLY A 114
LEU A 115
LEU A  82
 None
 0.75A 4po0A-1wfmA:
undetectable		 4po0A-1wfmA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1wfm SYNAPTOTAGMIN XIII
(Homo
sapiens) 		5 / 8 GLY A  77
LEU A  78
GLN A  62
VAL A  52
LEU A  92
 None
 1.49A 6czmD-1wfmA:
undetectable
6czmF-1wfmA:
undetectable		 6czmD-1wfmA:
19.88
6czmF-1wfmA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 1wfm SYNAPTOTAGMIN XIII
(Homo
sapiens) 		5 / 12 VAL A  30
LEU A  28
LEU A  15
THR A  63
LEU A  92
 None
 1.13A 6f6iA-1wfmA:
undetectable
6f6iB-1wfmA:
undetectable		 6f6iA-1wfmA:
22.14
6f6iB-1wfmA:
20.45