SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DTL_A_BEPA205_1 (CARDIAC TROPONIN C)	1wg6	HYPOTHETICAL PROTEIN (RIKEN CDNA 2810455B10) (Mus musculus)	5 / 12	ALA A 68 ILE A 62 LEU A 80 LEU A 116 MET A 104	None	1.02A	1dtlA-1wg6A: undetectable	1dtlA-1wg6A: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WLJ_A_SPMA1303_1 (POTASSIUM CHANNEL)	1wg6	HYPOTHETICAL PROTEIN (RIKEN CDNA 2810455B10) (Mus musculus)	3 / 3	ARG A 120 ARG A 121 PRO A 124	None	1.03A	2wljA-1wg6A: undetectable	2wljA-1wg6A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S56_A_ROCA201_2 (PROTEASE)	1wg6	HYPOTHETICAL PROTEIN (RIKEN CDNA 2810455B10) (Mus musculus)	5 / 9	LEU A 116 GLY A 66 ILE A 63 ILE A 114 ILE A 29	None	1.09A	3s56B-1wg6A: undetectable	3s56B-1wg6A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IK1_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	1wg6	HYPOTHETICAL PROTEIN (RIKEN CDNA 2810455B10) (Mus musculus)	4 / 5	LEU A 89 GLY A 56 ASP A 78 ILE A 59	None	1.00A	5ik1A-1wg6A: undetectable	5ik1A-1wg6A: 16.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DTL_A_BEPA205_1","CARDIAC TROPONIN C","1wg6","HYPOTHETICAL PROTEIN (RIKEN CDNA 2810455B10)","Mus musculus",5,"ALA A  68;ILE A  62;LEU A  80;LEU A 116;MET A 104","None","1.02A","1dtlA-1wg6A:undetectable","1dtlA-1wg6A:20.69"],["2WLJ_A_SPMA1303_1","POTASSIUM CHANNEL","1wg6","HYPOTHETICAL PROTEIN (RIKEN CDNA 2810455B10)","Mus musculus",3,"ARG A 120;ARG A 121;PRO A 124","None","1.03A","2wljA-1wg6A:undetectable","2wljA-1wg6A:20.28"],["3S56_A_ROCA201_2","PROTEASE;PROTEASE","1wg6","HYPOTHETICAL PROTEIN (RIKEN CDNA 2810455B10)","Mus musculus",5,"LEU A 116;GLY A  66;ILE A  63;ILE A 114;ILE A  29","None","1.09A","3s56B-1wg6A:undetectable","3s56B-1wg6A:21.88"],["5IK1_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","1wg6","HYPOTHETICAL PROTEIN (RIKEN CDNA 2810455B10)","Mus musculus",4,"LEU A  89;GLY A  56;ASP A  78;ILE A  59","None","1.00A","5ik1A-1wg6A:undetectable","5ik1A-1wg6A:16.67"]]