SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wgq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1wgq FYVE, RHOGEF AND PH
DOMAIN CONTAINING 6
ETHANOL DECREASED 4
(Mus
musculus) 		4 / 6 THR A  38
PHE A  29
PHE A  83
TYR A  81
 None
 1.33A 3elzB-1wgqA:
undetectable		 3elzB-1wgqA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 1wgq ETHANOL DECREASED 4
FYVE, RHOGEF AND PH
DOMAIN CONTAINING 6
(Mus
musculus) 		4 / 8 PHE A  83
PHE A  71
PHE A  29
LEU A  53
 None
 0.93A 4ejgB-1wgqA:
undetectable		 4ejgB-1wgqA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1wgq ETHANOL DECREASED 4
FYVE, RHOGEF AND PH
DOMAIN CONTAINING 6
(Mus
musculus) 		4 / 8 VAL A  58
LEU A  73
TYR A  81
GLN A  51
 None
 0.97A 4ma7A-1wgqA:
undetectable		 4ma7A-1wgqA:
21.37