SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wh4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADX_B_IMNB3_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1wh4	INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 (Mus musculus)	5 / 12	GLY A 89 ALA A 45 ILE A 98 LEU A 77 ILE A 18	None	1.03A	3adxB-1wh4A: undetectable	3adxB-1wh4A: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUM_B_IMNB501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1wh4	INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 (Mus musculus)	5 / 11	GLY A 89 ALA A 45 ILE A 98 LEU A 77 ILE A 18	None	1.04A	4xumB-1wh4A: undetectable	4xumB-1wh4A: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TWJ_D_SAMD201_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H)	1wh4	INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 (Mus musculus)	5 / 11	LEU A 91 ILE A 18 LEU A 107 THR A 13 LEU A 12	None	0.95A	5twjD-1wh4A: undetectable	5twjD-1wh4A: 21.12