SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1whw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		4 / 6 HIS A  91
GLY A  62
ALA A  95
GLU A  98
 None
 0.86A 1dmaB-1whwA:
undetectable		 1dmaB-1whwA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		5 / 12 GLY A  62
GLY A  38
SER A 114
GLU A  90
ALA A  92
 None
 0.93A 3kkzB-1whwA:
undetectable		 3kkzB-1whwA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		4 / 8 HIS A  91
GLY A  62
ALA A  95
GLU A  98
 None
 0.89A 3u9hA-1whwA:
undetectable		 3u9hA-1whwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		4 / 8 HIS A  91
GLY A  62
ALA A  95
GLU A  98
 None
 0.86A 3u9hB-1whwA:
undetectable		 3u9hB-1whwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		4 / 8 HIS A  91
GLY A  62
ALA A  95
GLU A  98
 None
 0.84A 4bjcA-1whwA:
undetectable		 4bjcA-1whwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		3 / 3 TYR A  47
ARG A 107
SER A  46
 None
 0.99A 4dr2I-1whwA:
undetectable
4dr2J-1whwA:
2.7		 4dr2I-1whwA:
22.22
4dr2J-1whwA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		4 / 7 HIS A  91
GLY A  62
ALA A  95
GLU A  98
 None
 0.84A 4hyfA-1whwA:
undetectable		 4hyfA-1whwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		4 / 8 HIS A  91
GLY A  62
ALA A  95
GLU A  98
 None
 0.84A 4hyfB-1whwA:
undetectable		 4hyfB-1whwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		4 / 8 HIS A  91
GLY A  62
ALA A  95
GLU A  98
 None
 0.86A 4hyfC-1whwA:
undetectable		 4hyfC-1whwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		3 / 3 TYR A  47
ARG A 107
SER A  46
 None
 0.82A 4lf7I-1whwA:
undetectable
4lf7J-1whwA:
2.5		 4lf7I-1whwA:
22.22
4lf7J-1whwA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1whw HYPOTHETICAL PROTEIN
RIKEN CDNA
1200009A02
(Mus
musculus) 		3 / 3 TYR A  47
ARG A 107
SER A  46
 None
 0.82A 4lf8I-1whwA:
undetectable
4lf8J-1whwA:
2.5		 4lf8I-1whwA:
22.22
4lf8J-1whwA:
16.51