SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wi5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1wi5 RRP5 PROTEIN HOMOLOG
(Homo
sapiens) 		3 / 3 ARG A 238
GLU A 235
GLN A 234
 None
 0.94A 2p16A-1wi5A:
undetectable		 2p16A-1wi5A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1wi5 RRP5 PROTEIN HOMOLOG
(Homo
sapiens) 		4 / 8 LEU A 203
VAL A 266
VAL A 217
LEU A 197
 None
 0.95A 4puoC-1wi5A:
undetectable		 4puoC-1wi5A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1wi5 RRP5 PROTEIN HOMOLOG
(Homo
sapiens) 		4 / 8 LEU A 203
VAL A 266
VAL A 217
LEU A 197
 None
 0.91A 4pwdA-1wi5A:
undetectable		 4pwdA-1wi5A:
10.70