SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ID5_A_T27A601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	1wic	HYPOTHETICAL PROTEIN RIKEN CDNA 6030424E15 (Mus musculus)	5 / 12	LEU A 131 VAL A 82 VAL A 55 TYR A 63 PHE A 29	None	1.43A	4id5A-1wicA: 0.0	4id5A-1wicA: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IDK_A_T27A601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	1wic	HYPOTHETICAL PROTEIN RIKEN CDNA 6030424E15 (Mus musculus)	5 / 12	LEU A 131 VAL A 82 VAL A 55 TYR A 63 PHE A 29	None	1.45A	4idkA-1wicA: 0.0	4idkA-1wicA: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IFY_A_T27A601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	1wic	HYPOTHETICAL PROTEIN RIKEN CDNA 6030424E15 (Mus musculus)	5 / 12	LEU A 131 VAL A 82 VAL A 55 TYR A 63 PHE A 29	None	1.43A	4ifyA-1wicA: 0.0	4ifyA-1wicA: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IG3_A_T27A601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	1wic	HYPOTHETICAL PROTEIN RIKEN CDNA 6030424E15 (Mus musculus)	5 / 12	LEU A 131 VAL A 82 VAL A 55 TYR A 63 PHE A 29	None	1.44A	4ig3A-1wicA: 0.0	4ig3A-1wicA: 14.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4ID5_A_T27A601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","1wic","HYPOTHETICAL PROTEIN RIKEN CDNA 6030424E15","Mus musculus",5,"LEU A 131;VAL A  82;VAL A  55;TYR A  63;PHE A  29","None","1.43A","4id5A-1wicA:0.0","4id5A-1wicA:14.42"],["4IDK_A_T27A601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","1wic","HYPOTHETICAL PROTEIN RIKEN CDNA 6030424E15","Mus musculus",5,"LEU A 131;VAL A  82;VAL A  55;TYR A  63;PHE A  29","None","1.45A","4idkA-1wicA:0.0","4idkA-1wicA:14.42"],["4IFY_A_T27A601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","1wic","HYPOTHETICAL PROTEIN RIKEN CDNA 6030424E15","Mus musculus",5,"LEU A 131;VAL A  82;VAL A  55;TYR A  63;PHE A  29","None","1.43A","4ifyA-1wicA:0.0","4ifyA-1wicA:14.42"],["4IG3_A_T27A601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","1wic","HYPOTHETICAL PROTEIN RIKEN CDNA 6030424E15","Mus musculus",5,"LEU A 131;VAL A  82;VAL A  55;TYR A  63;PHE A  29","None","1.44A","4ig3A-1wicA:0.0","4ig3A-1wicA:14.42"]]