SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wif'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 1wif RIKEN CDNA
4930408O21
(Mus
musculus) 		4 / 6 ASN A  58
HIS A  55
ALA A  63
GLY A  60
 None
 1.11A 1gfzA-1wifA:
undetectable		 1gfzA-1wifA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1wif RIKEN CDNA
4930408O21
(Mus
musculus) 		4 / 8 LEU A  40
GLY A  66
ILE A  67
LEU A  42
 None
 0.70A 2o4nB-1wifA:
undetectable		 2o4nB-1wifA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1wif RIKEN CDNA
4930408O21
(Mus
musculus) 		4 / 7 VAL A  35
ILE A  97
GLY A 100
THR A 101
 None
 0.69A 2xrzB-1wifA:
undetectable		 2xrzB-1wifA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1wif RIKEN CDNA
4930408O21
(Mus
musculus) 		4 / 6 ASN A  58
HIS A  55
ALA A  63
GLY A  60
 None
 1.12A 3dd1A-1wifA:
undetectable		 3dd1A-1wifA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1wif RIKEN CDNA
4930408O21
(Mus
musculus) 		4 / 6 ASN A  58
HIS A  55
ALA A  63
GLY A  60
 None
 1.16A 3ddsA-1wifA:
undetectable		 3ddsA-1wifA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1wif RIKEN CDNA
4930408O21
(Mus
musculus) 		4 / 6 ASN A  58
HIS A  55
ALA A  63
GLY A  60
 None
 1.15A 3ddsB-1wifA:
undetectable		 3ddsB-1wifA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1wif RIKEN CDNA
4930408O21
(Mus
musculus) 		4 / 6 ASN A  58
HIS A  55
ALA A  63
GLY A  60
 None
 1.15A 3ddwA-1wifA:
undetectable		 3ddwA-1wifA:
10.39