SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wir'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1wir PROTEIN ARGININE
N-METHYLTRANSFERASE
3
(Mus
musculus) 		3 / 3 THR A 112
GLU A 108
ASP A  44
 None
 0.69A 1nt2A-1wirA:
undetectable		 1nt2A-1wirA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 1wir PROTEIN ARGININE
N-METHYLTRANSFERASE
3
(Mus
musculus) 		3 / 3 CYH A  18
CYH A  35
HIS A  34
 ZN  A 201 (-2.3A)
ZN  A 201 ( 4.3A)
ZN  A 201 (-3.4A)
 0.88A 2iwkA-1wirA:
undetectable		 2iwkA-1wirA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 1wir PROTEIN ARGININE
N-METHYLTRANSFERASE
3
(Mus
musculus) 		3 / 3 CYH A  18
CYH A  35
HIS A  34
 ZN  A 201 (-2.3A)
ZN  A 201 ( 4.3A)
ZN  A 201 (-3.4A)
 0.88A 2iwkB-1wirA:
undetectable		 2iwkB-1wirA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1wir PROTEIN ARGININE
N-METHYLTRANSFERASE
3
(Mus
musculus) 		3 / 3 CYH A  18
CYH A  35
HIS A  34
 ZN  A 201 (-2.3A)
ZN  A 201 ( 4.3A)
ZN  A 201 (-3.4A)
 0.84A 3dtuB-1wirA:
undetectable		 3dtuB-1wirA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1wir PROTEIN ARGININE
N-METHYLTRANSFERASE
3
(Mus
musculus) 		3 / 3 CYH A  18
CYH A  35
HIS A  34
 ZN  A 201 (-2.3A)
ZN  A 201 ( 4.3A)
ZN  A 201 (-3.4A)
 0.83A 3dtuD-1wirA:
undetectable		 3dtuD-1wirA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 1wir PROTEIN ARGININE
N-METHYLTRANSFERASE
3
(Mus
musculus) 		4 / 7 ASN A  79
PRO A  80
TRP A  83
PHE A  63
 None
 1.30A 4v32C-1wirA:
0.0		 4v32C-1wirA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1wir PROTEIN ARGININE
N-METHYLTRANSFERASE
3
(Mus
musculus) 		4 / 4 ARG A  65
ILE A  61
TYR A  57
ILE A  43
 None
 1.20A 5odhG-1wirA:
undetectable		 5odhG-1wirA:
11.11