SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1wj4 KIAA0794 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  85
THR A  87
LEU A 103
LEU A 108
GLY A 107
 None
 1.29A 1d4fA-1wj4A:
undetectable		 1d4fA-1wj4A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1wj4 KIAA0794 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  85
THR A  87
LEU A 103
LEU A 108
GLY A 107
 None
 1.32A 3g1uB-1wj4A:
undetectable		 3g1uB-1wj4A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1wj4 KIAA0794 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  85
THR A  87
LEU A 103
LEU A 108
GLY A 107
 None
 1.32A 3g1uC-1wj4A:
undetectable		 3g1uC-1wj4A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1wj4 KIAA0794 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  85
THR A  87
LEU A 103
LEU A 108
GLY A 107
 None
 1.29A 3g1uD-1wj4A:
undetectable		 3g1uD-1wj4A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1wj4 KIAA0794 PROTEIN
(Homo
sapiens) 		5 / 9 LEU A  66
ARG A  92
THR A  87
VAL A 114
LEU A  46
 None
 1.24A 3unaA-1wj4A:
1.4		 3unaA-1wj4A:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1wj4 KIAA0794 PROTEIN
(Homo
sapiens) 		5 / 9 LEU A  66
ARG A  92
THR A  87
VAL A 114
LEU A  46
 None
 1.24A 3unaB-1wj4A:
1.5		 3unaB-1wj4A:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wj4 KIAA0794 PROTEIN
(Homo
sapiens) 		4 / 5 ILE A  58
LEU A  60
ARG A  49
LEU A  85
 None
 0.82A 6nmpN-1wj4A:
undetectable
6nmpW-1wj4A:
undetectable		 6nmpN-1wj4A:
12.06
6nmpW-1wj4A:
16.94