SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wj5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))
1wj5 HYPOTHETICAL PROTEIN
(RIKEN CDNA
0610009H20)

(Mus
musculus)
3 / 3 LEU A  51
SER A  22
ASN A  82
None
0.75A 1bx4A-1wj5A:
undetectable
1bx4A-1wj5A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)
1wj5 HYPOTHETICAL PROTEIN
(RIKEN CDNA
0610009H20)

(Mus
musculus)
3 / 3 SER A  73
ARG A  78
GLN A  77
None
1.02A 2xnrA-1wj5A:
undetectable
2xnrA-1wj5A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1wj5 HYPOTHETICAL PROTEIN
(RIKEN CDNA
0610009H20)

(Mus
musculus)
4 / 7 ILE A  25
LEU A  42
PHE A  80
ARG A  54
None
1.13A 2zxwN-1wj5A:
undetectable
2zxwW-1wj5A:
undetectable
2zxwN-1wj5A:
13.92
2zxwW-1wj5A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)
1wj5 HYPOTHETICAL PROTEIN
(RIKEN CDNA
0610009H20)

(Mus
musculus)
3 / 3 TYR A 105
ASP A  97
ASP A 101
None
0.80A 4a6eA-1wj5A:
3.3
4a6eA-1wj5A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1wj5 HYPOTHETICAL PROTEIN
(RIKEN CDNA
0610009H20)

(Mus
musculus)
3 / 3 GLN A  30
THR A 108
THR A 107
None
0.76A 4fu9A-1wj5A:
undetectable
4fu9A-1wj5A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1wj5 HYPOTHETICAL PROTEIN
(RIKEN CDNA
0610009H20)

(Mus
musculus)
3 / 3 GLN A  30
THR A 108
THR A 107
None
0.77A 4fufA-1wj5A:
undetectable
4fufA-1wj5A:
21.72