SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wjm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  87
ARG A  69
GLY A   1
 None
 1.01A 1jffB-1wjmA:
undetectable		 1jffB-1wjmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  87
ARG A  69
GLY A   1
 None
 1.01A 2hxfB-1wjmA:
undetectable		 2hxfB-1wjmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  87
ARG A  69
GLY A   1
 None
 1.01A 2hxhB-1wjmA:
undetectable		 2hxhB-1wjmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		4 / 5 PRO A  58
PRO A  64
GLY A  45
TYR A  47
 None
 1.09A 2jkjD-1wjmA:
undetectable		 2jkjD-1wjmA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		4 / 5 PRO A  58
PRO A  64
GLY A  45
TYR A  47
 None
 1.08A 2jkjF-1wjmA:
undetectable		 2jkjF-1wjmA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  87
ARG A  69
GLY A   1
 None
 1.01A 2p4nB-1wjmA:
undetectable		 2p4nB-1wjmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  87
ARG A  69
GLY A   1
 None
 1.01A 2wbeB-1wjmA:
undetectable		 2wbeB-1wjmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  87
ARG A  69
GLY A   1
 None
 1.01A 3dcoB-1wjmA:
undetectable		 3dcoB-1wjmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  87
ARG A  69
GLY A   1
 None
 1.00A 3edlB-1wjmA:
undetectable		 3edlB-1wjmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  87
ARG A  69
GLY A   1
 None
 0.98A 3iz0B-1wjmA:
undetectable		 3iz0B-1wjmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		6 / 12 GLY A   7
ASN A 113
LEU A 109
SER A 107
GLY A  72
LEU A  87
 None
 1.31A 4fzvA-1wjmA:
undetectable		 4fzvA-1wjmA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  44
LEU A  87
ARG A  69
 None
 0.92A 5hnwB-1wjmA:
undetectable		 5hnwB-1wjmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1wjm BETA-SPECTRIN III
(Homo
sapiens) 		5 / 12 GLU A   8
LEU A  89
LEU A  44
LEU A  87
ARG A  69
 None
 0.94A 5hnyB-1wjmA:
undetectable		 5hnyB-1wjmA:
16.35