SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wjr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1wjr KIAA1617 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  15
SER A  16
LEU A 110
ILE A  18
LEU A  44
 None
 1.23A 1kyvA-1wjrA:
undetectable
1kyvE-1wjrA:
undetectable		 1kyvA-1wjrA:
21.47
1kyvE-1wjrA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1wjr KIAA1617 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  44
GLY A  15
SER A  16
LEU A 110
ILE A  18
 None
 1.22A 1kyvB-1wjrA:
undetectable
1kyvC-1wjrA:
undetectable		 1kyvB-1wjrA:
21.47
1kyvC-1wjrA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1wjr KIAA1617 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  44
GLY A  15
SER A  16
LEU A 110
ILE A  18
 None
 1.25A 1kyvC-1wjrA:
undetectable
1kyvD-1wjrA:
undetectable		 1kyvC-1wjrA:
21.47
1kyvD-1wjrA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1wjr KIAA1617 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  44
GLY A  15
SER A  16
LEU A 110
ILE A  18
 None
 1.26A 1kyvD-1wjrA:
undetectable
1kyvE-1wjrA:
undetectable		 1kyvD-1wjrA:
21.47
1kyvE-1wjrA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 1wjr KIAA1617 PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 110
LEU A  44
VAL A  14
ILE A  31
VAL A  47
 None
 1.16A 4ok1A-1wjrA:
undetectable		 4ok1A-1wjrA:
19.11