SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wjt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 1wjt TRANSCRIPTION
ELONGATION FACTOR
S-II PROTEIN 3
(Mus
musculus) 		5 / 12 LEU A  15
LEU A  21
ALA A  58
LEU A  78
LEU A  50
 None
 1.11A 2oaxB-1wjtA:
undetectable		 2oaxB-1wjtA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 1wjt TRANSCRIPTION
ELONGATION FACTOR
S-II PROTEIN 3
(Mus
musculus) 		5 / 12 LEU A  15
LEU A  21
ALA A  58
LEU A  78
LEU A  50
 None
 1.06A 2oaxD-1wjtA:
undetectable		 2oaxD-1wjtA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 1wjt TRANSCRIPTION
ELONGATION FACTOR
S-II PROTEIN 3
(Mus
musculus) 		5 / 12 LEU A  15
LEU A  21
ALA A  58
LEU A  78
LEU A  50
 None
 1.08A 2oaxE-1wjtA:
undetectable		 2oaxE-1wjtA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 1wjt TRANSCRIPTION
ELONGATION FACTOR
S-II PROTEIN 3
(Mus
musculus) 		5 / 12 LEU A  15
GLU A  11
MET A  45
LEU A  49
LEU A  40
 None
 1.32A 4j24C-1wjtA:
undetectable		 4j24C-1wjtA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 1wjt TRANSCRIPTION
ELONGATION FACTOR
S-II PROTEIN 3
(Mus
musculus) 		4 / 4 LYS A  19
LEU A  15
ALA A  18
LEU A  14
 None
 1.33A 6gnrA-1wjtA:
undetectable		 6gnrA-1wjtA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 1wjt TRANSCRIPTION
ELONGATION FACTOR
S-II PROTEIN 3
(Mus
musculus) 		4 / 4 LYS A  19
LEU A  15
ALA A  18
LEU A  14
 None
 1.32A 6gnrB-1wjtA:
undetectable		 6gnrB-1wjtA:
21.90