SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1wju NEDD8 ULTIMATE
BUSTER-1
(Homo
sapiens) 		3 / 3 LEU A  22
PRO A  23
LEU A  26
 None
 0.24A 1hrkA-1wjuA:
undetectable		 1hrkA-1wjuA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wju NEDD8 ULTIMATE
BUSTER-1
(Homo
sapiens) 		3 / 3 LEU A  22
PRO A  23
LEU A  26
 None
 0.61A 2po5B-1wjuA:
undetectable		 2po5B-1wjuA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 1wju NEDD8 ULTIMATE
BUSTER-1
(Homo
sapiens) 		3 / 3 LEU A  22
PRO A  23
LEU A  26
 None
 0.29A 2qd5B-1wjuA:
undetectable		 2qd5B-1wjuA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wju NEDD8 ULTIMATE
BUSTER-1
(Homo
sapiens) 		3 / 3 LEU A  22
PRO A  23
LEU A  26
 None
 0.20A 3w1wB-1wjuA:
undetectable		 3w1wB-1wjuA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 1wju NEDD8 ULTIMATE
BUSTER-1
(Homo
sapiens) 		3 / 3 ASN A  58
GLU A  57
ARG A  46
 None
 1.09A 3wxoA-1wjuA:
undetectable		 3wxoA-1wjuA:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 1wju NEDD8 ULTIMATE
BUSTER-1
(Homo
sapiens) 		4 / 6 ARG A  43
GLY A  42
GLU A  44
GLN A  68
 None
 1.13A 4g0uA-1wjuA:
undetectable		 4g0uA-1wjuA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 1wju NEDD8 ULTIMATE
BUSTER-1
(Homo
sapiens) 		4 / 5 GLY A  42
ILE A  64
LYS A  67
GLN A  68
 None
 1.00A 4ma8C-1wjuA:
undetectable		 4ma8C-1wjuA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1wju NEDD8 ULTIMATE
BUSTER-1
(Homo
sapiens) 		4 / 6 GLU A  90
GLY A  72
ARG A  43
GLY A  42
 None
 0.83A 5cdnR-1wjuA:
undetectable
5cdnS-1wjuA:
undetectable		 5cdnR-1wjuA:
13.12
5cdnS-1wjuA:
20.92