SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wk0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)
1wk0 KIAA0970 PROTEIN
(Homo
sapiens)
4 / 7 VAL A  62
ALA A  97
ASP A  88
LEU A  89
None
0.81A 4l9iA-1wk0A:
undetectable
4l9iA-1wk0A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)
1wk0 KIAA0970 PROTEIN
(Homo
sapiens)
4 / 5 ALA A  97
VAL A  62
PHE A 116
ILE A  84
None
0.96A 5of1A-1wk0A:
undetectable
5of1A-1wk0A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)
1wk0 KIAA0970 PROTEIN
(Homo
sapiens)
4 / 5 ALA A  97
VAL A  62
PHE A 116
ILE A  84
None
0.90A 5of1B-1wk0A:
undetectable
5of1B-1wk0A:
18.44