SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wkb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 HIS A  53
SER A 532
GLY A 610
ASP A 612
MET A 651
 None
 0.99A 1ffyA-1wkbA:
25.1		 1ffyA-1wkbA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		6 / 11 ALA A  41
HIS A  50
GLY A  52
HIS A  53
GLY A 610
ASP A 612
 None
 0.63A 1pg2A-1wkbA:
28.8		 1pg2A-1wkbA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A  52
HIS A  53
GLY A 610
ASP A 612
PHE A 643
 None
 0.84A 1qu2A-1wkbA:
25.1		 1qu2A-1wkbA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 HIS A  50
GLY A  52
HIS A  53
GLY A 610
ASP A 612
 None
 0.99A 1qu2A-1wkbA:
25.1		 1qu2A-1wkbA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 HIS A  53
SER A 532
GLY A 610
ASP A 612
MET A 651
 None
 0.99A 1qu2A-1wkbA:
25.1		 1qu2A-1wkbA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 7 PHE A 159
SER A 160
ILE A 526
THR A  83
 None
 0.89A 1sbrB-1wkbA:
undetectable		 1sbrB-1wkbA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 7 PHE A 159
SER A 160
ILE A 526
THR A 152
 None
 0.92A 1sbrB-1wkbA:
undetectable		 1sbrB-1wkbA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 ASP A 555
GLU A 164
TYR A 538
 None
 0.73A 1wsvA-1wkbA:
0.2		 1wsvA-1wkbA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 5 GLY A  84
PRO A 122
ALA A  91
ILE A  90
 SO4  A 901 (-3.3A)
None
None
None
 0.91A 2aofA-1wkbA:
undetectable		 2aofA-1wkbA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 PHE A 162
PHE A 568
PHE A 629
 None
 0.79A 2od9A-1wkbA:
undetectable		 2od9A-1wkbA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 GLY A 194
ASP A 195
SER A  85
 SO4  A 901 ( 4.8A)
SO4  A 906 ( 4.9A)
SO4  A 901 (-2.8A)
 0.62A 2qhfA-1wkbA:
undetectable		 2qhfA-1wkbA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 ASP A 531
ILE A 163
PHE A  42
ALA A  41
HIS A  81
 None
 1.50A 2qmjA-1wkbA:
undetectable		 2qmjA-1wkbA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 PHE A 162
PHE A 568
PHE A 629
 None
 0.79A 2qqgA-1wkbA:
undetectable		 2qqgA-1wkbA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 5 PHE A 162
PHE A 621
PHE A 629
ILE A  38
 None
 1.34A 2v0mD-1wkbA:
undetectable		 2v0mD-1wkbA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		6 / 11 ALA A  41
HIS A  50
GLY A  52
HIS A  53
GLY A 610
ASP A 612
 None
 0.74A 2x1lA-1wkbA:
28.6		 2x1lA-1wkbA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		6 / 12 ALA A  41
HIS A  50
GLY A  52
HIS A  53
GLY A 610
ASP A 612
 None
 0.72A 2x1lB-1wkbA:
30.4		 2x1lB-1wkbA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 11 ALA A  41
HIS A  50
HIS A  53
GLY A 610
ASP A 612
 None
 0.71A 2x1lC-1wkbA:
30.3		 2x1lC-1wkbA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 11 HIS A  50
GLY A  52
HIS A  53
GLY A 610
ASP A 612
 None
 0.55A 2x1lC-1wkbA:
30.3		 2x1lC-1wkbA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 7 ARG A 607
PHE A  76
ILE A  59
ASN A 641
 None
 1.19A 2zseA-1wkbA:
undetectable		 2zseA-1wkbA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 6 ILE A 439
GLU A 438
ILE A 211
ASP A 277
 None
 0.95A 3a7eA-1wkbA:
undetectable		 3a7eA-1wkbA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 MET A 440
VAL A 322
ALA A 227
VAL A 325
MET A 323
 None
 1.19A 3dl9A-1wkbA:
undetectable		 3dl9A-1wkbA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 10 VAL A  40
PHE A  76
PHE A 137
ALA A 140
ILE A 677
 None
 1.08A 3me6A-1wkbA:
undetectable		 3me6A-1wkbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 ASN A 668
VAL A 673
VAL A 694
PHE A 661
GLU A 647
 None
 1.32A 3medA-1wkbA:
undetectable
3medB-1wkbA:
undetectable		 3medA-1wkbA:
21.35
3medB-1wkbA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 8 TYR A 535
TYR A 539
TYR A  57
LEU A  45
 None
 1.44A 3uzzB-1wkbA:
undetectable		 3uzzB-1wkbA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 TRP A 465
VAL A 525
TRP A 520
 None
 1.33A 3zq8A-1wkbA:
undetectable
3zq8B-1wkbA:
undetectable		 3zq8A-1wkbA:
1.85
3zq8B-1wkbA:
1.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 6 GLN A 276
ARG A 278
ASP A 208
GLU A 425
 None
 1.49A 4azvA-1wkbA:
undetectable		 4azvA-1wkbA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 7 VAL A 753
GLN A 754
TYR A 758
LEU A 680
 None
 1.24A 4hxyB-1wkbA:
undetectable		 4hxyB-1wkbA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O79_B_ASCB303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 6 LYS A  32
LYS A  35
TYR A  37
ALA A 537
 None
 1.26A 4o79B-1wkbA:
0.1		 4o79B-1wkbA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 6 LEU A  75
ASP A 605
ILE A 541
PRO A 635
 None
 1.07A 4xi3C-1wkbA:
undetectable		 4xi3C-1wkbA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 LEU A  75
ASP A 605
ILE A 541
 None
 0.49A 4xi3D-1wkbA:
undetectable		 4xi3D-1wkbA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 9 TYR A 758
ILE A 760
THR A 798
LEU A 675
LEU A 697
 None
 1.25A 4ze0A-1wkbA:
1.1		 4ze0A-1wkbA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 ARG A 148
PRO A  25
ASN A  73
 None
 1.10A 5jwaA-1wkbA:
undetectable
5jwaH-1wkbA:
undetectable		 5jwaA-1wkbA:
21.47
5jwaH-1wkbA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 6 LEU A 613
ILE A 500
THR A 619
MET A 485
 None
 1.42A 5ljeA-1wkbA:
undetectable		 5ljeA-1wkbA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 THR A 516
THR A 533
LEU A 170
 None
 0.69A 5m66D-1wkbA:
undetectable		 5m66D-1wkbA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A 237
VAL A 412
TYR A 401
ILE A 400
ALA A 329
 None
None
SO4  A 907 (-4.7A)
None
None
 0.98A 5n0sA-1wkbA:
undetectable		 5n0sA-1wkbA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A 237
VAL A 412
TYR A 401
ILE A 400
ALA A 329
 None
None
SO4  A 907 (-4.7A)
None
None
 1.01A 5n0tA-1wkbA:
undetectable		 5n0tA-1wkbA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A 237
VAL A 412
TYR A 401
ILE A 400
ALA A 329
 None
None
SO4  A 907 (-4.7A)
None
None
 1.02A 5n0tB-1wkbA:
undetectable		 5n0tB-1wkbA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A 237
VAL A 412
TYR A 401
ILE A 400
ALA A 329
 None
None
SO4  A 907 (-4.7A)
None
None
 0.96A 5n0wB-1wkbA:
undetectable		 5n0wB-1wkbA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A 237
VAL A 412
TYR A 401
ILE A 400
ALA A 329
 None
None
SO4  A 907 (-4.7A)
None
None
 1.01A 5n0xA-1wkbA:
undetectable		 5n0xA-1wkbA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A 237
VAL A 412
TYR A 401
ILE A 400
ALA A 329
 None
None
SO4  A 907 (-4.7A)
None
None
 0.98A 5n4iA-1wkbA:
undetectable		 5n4iA-1wkbA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_0
(REGULATORY PROTEIN
TETR)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		5 / 12 MET A 678
ALA A  54
VAL A  40
CYH A 608
PHE A  76
 None
 1.48A 5vlmC-1wkbA:
0.0		 5vlmC-1wkbA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 6 ARG A  65
VAL A 791
TRP A 806
GLU A 807
 None
 1.50A 6auqA-1wkbA:
undetectable
6auqB-1wkbA:
undetectable		 6auqA-1wkbA:
7.20
6auqB-1wkbA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 TYR A 109
HIS A  48
PHE A 129
 None
 0.94A 6esmA-1wkbA:
undetectable		 6esmA-1wkbA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		4 / 5 ILE A 163
THR A 516
THR A 533
LEU A 170
 None
 0.87A 6f3mD-1wkbA:
undetectable		 6f3mD-1wkbA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wkb LEUCYL-TRNA
SYNTHETASE
(Pyrococcus
horikoshii) 		3 / 3 ARG A  68
PHE A 797
PHE A  76
 None
 0.97A 6nknC-1wkbA:
undetectable
6nknJ-1wkbA:
undetectable		 6nknC-1wkbA:
15.67
6nknJ-1wkbA:
5.85