SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wkr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 7 LEU A 105
THR A  38
GLY A 108
LEU A 143
 None
 0.84A 1gtiB-1wkrA:
undetectable		 1gtiB-1wkrA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 4 GLY A 103
ASP A  95
GLY A  70
THR A 116
 None
SO4  A 904 (-4.2A)
SO4  A 902 (-3.3A)
None
 0.99A 1hxbB-1wkrA:
7.6		 1hxbB-1wkrA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_B_SAMB500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 10 ASN A 141
LEU A 142
GLY A 136
SER A 134
PHE A 133
 None
 1.16A 2c2bA-1wkrA:
0.0
2c2bB-1wkrA:
0.0		 2c2bA-1wkrA:
24.08
2c2bB-1wkrA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_D_SAMD500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 9 ASN A 141
LEU A 142
GLY A 136
SER A 134
PHE A 133
 None
 1.20A 2c2bC-1wkrA:
0.0
2c2bD-1wkrA:
0.0		 2c2bC-1wkrA:
24.08
2c2bD-1wkrA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		3 / 3 PRO A 275
THR A 150
PRO A 149
 None
 0.84A 2d55C-1wkrA:
undetectable		 2d55C-1wkrA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 4 ASP A  13
ASP A  32
ASP A  99
GLY A 103
 None
None
SO4  A 905 ( 4.4A)
None
 1.43A 2igtC-1wkrA:
undetectable		 2igtC-1wkrA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 6 LEU A 296
SER A 222
ASP A 299
GLU A 302
 None
 1.11A 2j2pE-1wkrA:
undetectable
2j2pF-1wkrA:
undetectable		 2j2pE-1wkrA:
22.02
2j2pF-1wkrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASN A  37
ILE A 104
 None
 0.81A 2q64B-1wkrA:
7.1		 2q64B-1wkrA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASN A  37
ILE A 104
 None
 0.87A 2qakA-1wkrA:
7.3		 2qakA-1wkrA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASN A  37
ILE A 104
 None
 0.84A 2qakB-1wkrA:
7.2		 2qakB-1wkrA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		6 / 12 ASP A  32
GLY A  34
SER A  35
TYR A  63
ASP A 212
GLY A 214
 None
 0.32A 2v0zC-1wkrA:
36.9		 2v0zC-1wkrA:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 SER A 154
THR A   8
VAL A  15
GLN A  10
LEU A  30
 None
 1.45A 2xrlA-1wkrA:
undetectable		 2xrlA-1wkrA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 VAL A 145
TRP A 189
VAL A 110
SER A 124
ASN A 131
 None
 1.46A 2y00A-1wkrA:
undetectable		 2y00A-1wkrA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 VAL A 145
TRP A 189
VAL A 110
SER A 124
ASN A 131
 None
 1.43A 2y00B-1wkrA:
undetectable		 2y00B-1wkrA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 VAL A 145
TRP A 189
VAL A 110
SER A 124
ASN A 131
 None
 1.45A 2y01B-1wkrA:
undetectable		 2y01B-1wkrA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 7 ASP A 130
SER A  88
GLU A  72
ASP A  57
 None
 1.30A 3bc9A-1wkrA:
undetectable		 3bc9A-1wkrA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 5 LEU A  30
ASP A  32
ILE A 104
GLY A 214
 None
 0.44A 3bufA-1wkrA:
30.9		 3bufA-1wkrA:
27.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ASP A 212
GLY A 214
LEU A  30
ASP A  32
SER A  36
 None
 0.84A 3d91A-1wkrA:
36.5		 3d91A-1wkrA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ASP A 212
GLY A 214
SER A  65
LEU A  30
ASP A  32
 None
 0.84A 3d91A-1wkrA:
36.5		 3d91A-1wkrA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ASP A 212
GLY A 214
LEU A  30
ASP A  32
SER A  36
 None
 0.82A 3d91B-1wkrA:
36.6		 3d91B-1wkrA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 TYR A  63
GLY A  90
ALA A  54
VAL A  61
PHE A  68
 None
 1.02A 3dmfA-1wkrA:
undetectable		 3dmfA-1wkrA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 TYR A  63
GLY A  90
ALA A  54
VAL A  61
PHE A  68
 None
 1.01A 3dmhA-1wkrA:
undetectable		 3dmhA-1wkrA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 4 GLY A 103
ASP A  95
GLY A  70
THR A 116
 None
SO4  A 904 (-4.2A)
SO4  A 902 (-3.3A)
None
 0.89A 3k4vC-1wkrA:
7.5		 3k4vC-1wkrA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 8 LEU A 143
VAL A   5
LEU A  79
VAL A  16
LEU A 105
 None
 1.41A 3kp6A-1wkrA:
undetectable
3kp6B-1wkrA:
undetectable		 3kp6A-1wkrA:
18.88
3kp6B-1wkrA:
18.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		6 / 12 ASP A  32
GLY A  34
GLY A  64
ASP A 212
THR A 215
ILE A 307
 None
 0.49A 3prsA-1wkrA:
35.6		 3prsA-1wkrA:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ASP A 111
ASP A 212
GLY A 214
ASP A  32
ILE A 104
 None
 1.11A 3prsA-1wkrA:
35.6		 3prsA-1wkrA:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		7 / 12 ASP A  32
GLY A  64
PHE A  98
LEU A  30
ILE A 210
THR A 215
ILE A 307
 None
 1.38A 3pwwA-1wkrA:
35.4		 3pwwA-1wkrA:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 8 GLY A  34
SER A  35
TYR A  63
ASP A 212
THR A 216
 None
 0.34A 3pwwA-1wkrA:
35.5		 3pwwA-1wkrA:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		6 / 12 ASP A  32
GLY A  34
GLY A  64
ASP A 212
THR A 215
ILE A 307
 None
 0.30A 3q70A-1wkrA:
34.2		 3q70A-1wkrA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ILE A 210
ASP A 212
GLY A 214
ASP A  32
ILE A 104
 None
 0.60A 3q70A-1wkrA:
34.2		 3q70A-1wkrA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ILE A 210
ASP A 212
GLY A 214
GLY A  64
ASP A  32
 None
 0.65A 3q70A-1wkrA:
34.2		 3q70A-1wkrA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 6 SER A  35
TYR A  63
ASP A  99
THR A 216
 None
None
SO4  A 905 ( 4.4A)
None
 0.97A 3q70A-1wkrA:
34.2		 3q70A-1wkrA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ASP A  32
GLY A  34
GLY A  64
ASP A 212
ILE A 307
 None
 0.40A 3tneA-1wkrA:
35.3		 3tneA-1wkrA:
32.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ILE A 210
ASP A 212
GLY A 214
ASP A  32
ILE A 104
 None
 0.58A 3tneA-1wkrA:
35.3		 3tneA-1wkrA:
32.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ILE A 210
ASP A 212
GLY A 214
GLY A  64
ASP A  32
 None
 0.82A 3tneA-1wkrA:
35.3		 3tneA-1wkrA:
32.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 6 SER A  35
TYR A  63
THR A 215
THR A 216
 None
 0.40A 3tneA-1wkrA:
35.4		 3tneA-1wkrA:
32.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 6 SER A  35
VAL A 101
THR A 215
THR A 216
 None
 1.14A 3tneA-1wkrA:
35.4		 3tneA-1wkrA:
32.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ASP A  32
GLY A  34
GLY A  64
ASP A 212
ILE A 307
 None
 0.43A 3tneB-1wkrA:
35.3		 3tneB-1wkrA:
32.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ILE A 210
ASP A 212
GLY A 214
ASP A  32
ILE A 104
 None
 0.63A 3tneB-1wkrA:
35.3		 3tneB-1wkrA:
32.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 ILE A 210
ASP A 212
GLY A 214
GLY A  64
ASP A  32
 None
 0.79A 3tneB-1wkrA:
35.3		 3tneB-1wkrA:
32.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 7 SER A  35
TYR A  63
ILE A 104
THR A 215
THR A 216
 None
 0.53A 3tneB-1wkrA:
35.3		 3tneB-1wkrA:
32.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 GLY A  90
ALA A  92
ILE A  89
SER A  60
VAL A  59
 None
 0.93A 4azvA-1wkrA:
undetectable		 4azvA-1wkrA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 10 PHE A 162
LEU A  79
VAL A  77
LEU A 105
VAL A  18
 None
 0.92A 4e3hA-1wkrA:
undetectable		 4e3hA-1wkrA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		3 / 3 GLN A 263
THR A 264
THR A 259
 None
 0.79A 4fu9A-1wkrA:
undetectable		 4fu9A-1wkrA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		3 / 3 GLN A 263
THR A 264
THR A 259
 None
 0.78A 4fufA-1wkrA:
0.0		 4fufA-1wkrA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 11 PHE A  98
GLY A 100
LEU A  30
GLY A 103
ALA A 187
 None
 1.19A 4l6v1-1wkrA:
undetectable
4l6v6-1wkrA:
undetectable		 4l6v1-1wkrA:
20.32
4l6v6-1wkrA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		3 / 3 ASP A 212
ASP A  32
ASN A  37
 None
 0.55A 4q5mA-1wkrA:
9.8		 4q5mA-1wkrA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 9 LEU A 160
GLY A 158
VAL A  16
VAL A  31
LEU A  30
 None
 1.09A 4qd3A-1wkrA:
undetectable		 4qd3A-1wkrA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 9 THR A  38
ILE A 104
GLY A 108
LEU A 143
LEU A 160
 None
 1.22A 4ze0A-1wkrA:
undetectable		 4ze0A-1wkrA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 LEU A 143
ILE A  84
VAL A  77
ILE A  89
PHE A  68
 None
 1.09A 5mugA-1wkrA:
undetectable		 5mugA-1wkrA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		3 / 3 LEU A 243
LEU A 242
TRP A 274
 None
 0.85A 5nwuA-1wkrA:
undetectable		 5nwuA-1wkrA:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		5 / 12 LEU A 142
SER A   4
ALA A   1
ALA A   2
GLY A   3
 None
 1.03A 5tzoB-1wkrA:
undetectable		 5tzoB-1wkrA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		4 / 6 GLN A  10
ASN A   9
VAL A  15
LEU A 105
 None
 1.21A 5xdhA-1wkrA:
undetectable
5xdhC-1wkrA:
undetectable		 5xdhA-1wkrA:
15.72
5xdhC-1wkrA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1wkr POLYPOROPEPSIN
(Irpex
lacteus) 		3 / 3 LEU A 217
ASN A 340
LEU A 267
 None
 0.72A 6exiD-1wkrA:
undetectable		 6exiD-1wkrA:
14.11