SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wlf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1wlf PEROXISOME
BIOGENESIS FACTOR 1
(Mus
musculus) 		3 / 3 LEU A  31
PRO A  32
LEU A  35
 None
 0.55A 1hrkA-1wlfA:
undetectable		 1hrkA-1wlfA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 1wlf PEROXISOME
BIOGENESIS FACTOR 1
(Mus
musculus) 		6 / 12 VAL A 108
ILE A 155
ILE A 145
ILE A 134
VAL A 106
LEU A 169
 None
 1.41A 1qhsA-1wlfA:
undetectable		 1qhsA-1wlfA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 1wlf PEROXISOME
BIOGENESIS FACTOR 1
(Mus
musculus) 		6 / 12 VAL A 108
ILE A 155
ILE A 145
ILE A 134
VAL A 106
LEU A 169
 None
 1.45A 1qhyA-1wlfA:
undetectable		 1qhyA-1wlfA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wlf PEROXISOME
BIOGENESIS FACTOR 1
(Mus
musculus) 		3 / 3 GLU A  62
GLU A  75
LEU A  94
 None
SO4  A 182 ( 4.8A)
None
 0.77A 1v8bB-1wlfA:
undetectable		 1v8bB-1wlfA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wlf PEROXISOME
BIOGENESIS FACTOR 1
(Mus
musculus) 		4 / 7 LYS A  83
LEU A  84
GLN A  82
LEU A  58
 None
 0.97A 5b3sP-1wlfA:
undetectable		 5b3sP-1wlfA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1wlf PEROXISOME
BIOGENESIS FACTOR 1
(Mus
musculus) 		4 / 5 SER A  51
ALA A  50
HIS A  53
LEU A  86
 None
 1.41A 5dzkc-1wlfA:
undetectable
5dzkq-1wlfA:
undetectable		 5dzkc-1wlfA:
22.47
5dzkq-1wlfA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 1wlf PEROXISOME
BIOGENESIS FACTOR 1
(Mus
musculus) 		3 / 3 VAL A 137
GLN A 105
CYH A 103
 None
 0.63A 5icxA-1wlfA:
undetectable
5icxE-1wlfA:
undetectable		 5icxA-1wlfA:
21.60
5icxE-1wlfA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 1wlf PEROXISOME
BIOGENESIS FACTOR 1
(Mus
musculus) 		3 / 3 VAL A 137
GLN A 105
CYH A 103
 None
 0.58A 5icxC-1wlfA:
0.0
5icxF-1wlfA:
undetectable		 5icxC-1wlfA:
21.60
5icxF-1wlfA:
11.11