SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wlh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		3 / 3 SER A 570
GLU A 616
GLU A 618
 None
 0.53A 1eqbD-1wlhA:
undetectable		 1eqbD-1wlhA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		3 / 3 SER A 570
GLU A 616
GLU A 618
 None
 0.53A 1eqbB-1wlhA:
undetectable		 1eqbB-1wlhA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		4 / 7 LEU A 795
ILE A 786
ALA A 807
ILE A 828
 None
 0.98A 1oniB-1wlhA:
undetectable
1oniC-1wlhA:
undetectable		 1oniB-1wlhA:
22.01
1oniC-1wlhA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		5 / 12 ALA A 670
GLY A 660
GLY A 658
ASP A 720
GLY A 750
 None
 1.02A 1sqfA-1wlhA:
undetectable		 1sqfA-1wlhA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		5 / 12 LEU A 733
ILE A 738
ASP A 678
GLY A 681
PHE A 691
 None
 1.08A 1zz1B-1wlhA:
undetectable
1zz1C-1wlhA:
undetectable		 1zz1B-1wlhA:
23.32
1zz1C-1wlhA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		4 / 8 PHE A 617
VAL A 645
THR A 644
ILE A 595
 None
 0.96A 2qbmA-1wlhA:
undetectable		 2qbmA-1wlhA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		5 / 12 ALA A 767
VAL A 765
THR A 855
PHE A 782
LYS A 781
 None
 1.13A 2v95A-1wlhA:
undetectable		 2v95A-1wlhA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		4 / 8 ALA A 670
ALA A 721
GLY A 750
ALA A 668
 None
 0.80A 2vh3B-1wlhA:
undetectable		 2vh3B-1wlhA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		4 / 8 ASP A 689
ALA A 676
TYR A 715
ASP A 686
 None
 1.00A 4k0bB-1wlhA:
undetectable		 4k0bB-1wlhA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		4 / 8 ASP A 689
ALA A 676
TYR A 715
ASP A 686
 None
 1.03A 4l7iB-1wlhA:
undetectable		 4l7iB-1wlhA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		5 / 12 ALA A 656
PHE A 672
ASN A 728
ILE A 674
VAL A 693
 None
 0.94A 4nkxD-1wlhA:
undetectable		 4nkxD-1wlhA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1wlh GELATION FACTOR
(Dictyostelium
discoideum) 		5 / 7 VAL A 615
ILE A 574
PHE A 591
VAL A 593
ILE A 595
 None
 1.45A 5bmvC-1wlhA:
undetectable		 5bmvC-1wlhA:
21.59