SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wlj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1wlj INTERFERON
STIMULATED GENE
20KDA
(Homo
sapiens) 		5 / 12 ARG A  21
ARG A  44
GLY A  24
PRO A  45
VAL A  56
 None
None
None
None
U5P  A 300 ( 4.9A)
 1.30A 2zznA-1wljA:
undetectable		 2zznA-1wljA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1wlj INTERFERON
STIMULATED GENE
20KDA
(Homo
sapiens) 		5 / 12 LEU A  98
PHE A  95
ILE A  77
ILE A 107
VAL A   8
 None
 1.02A 4nkxC-1wljA:
undetectable		 4nkxC-1wljA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1wlj INTERFERON
STIMULATED GENE
20KDA
(Homo
sapiens) 		5 / 12 LEU A  98
PHE A  95
ILE A  77
ILE A 107
VAL A   8
 None
 1.02A 4nkxD-1wljA:
undetectable		 4nkxD-1wljA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 1wlj INTERFERON
STIMULATED GENE
20KDA
(Homo
sapiens) 		5 / 10 CYH A  28
LEU A  25
LEU A  98
ALA A  97
LEU A  91
 None
 1.14A 4p65A-1wljA:
undetectable
4p65B-1wljA:
undetectable
4p65F-1wljA:
undetectable
4p65H-1wljA:
undetectable		 4p65A-1wljA:
7.84
4p65B-1wljA:
11.39
4p65F-1wljA:
11.39
4p65H-1wljA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 1wlj INTERFERON
STIMULATED GENE
20KDA
(Homo
sapiens) 		5 / 11 CYH A  28
LEU A  25
LEU A  98
ALA A  97
LEU A  91
 None
 1.14A 4p65C-1wljA:
undetectable
4p65D-1wljA:
undetectable
4p65J-1wljA:
undetectable
4p65L-1wljA:
undetectable		 4p65C-1wljA:
7.84
4p65D-1wljA:
11.39
4p65J-1wljA:
11.39
4p65L-1wljA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 1wlj INTERFERON
STIMULATED GENE
20KDA
(Homo
sapiens) 		5 / 11 LEU A  91
CYH A  28
LEU A  25
LEU A  98
ALA A  97
 None
 1.14A 4p65B-1wljA:
undetectable
4p65D-1wljA:
undetectable
4p65G-1wljA:
undetectable
4p65H-1wljA:
undetectable		 4p65B-1wljA:
11.39
4p65D-1wljA:
11.39
4p65G-1wljA:
7.84
4p65H-1wljA:
11.39